Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wangjie Lv"'
Autor:
Yang Ouyang, Gaokun Qiu, Xinjie zhao, Benzhe Su, Disheng Feng, Wangjie Lv, Qiuhui Xuan, Lichao Wang, Di Yu, Qingqing Wang, Xiaohui Lin, Tangchun Wu, Guowang Xu
Publikováno v:
Global Challenges, Vol 5, Iss 4, Pp n/a-n/a (2021)
Abstract In a Chinese prospective cohort, 500 patients with new‐onset type 2 diabetes (T2D) within 4.61 years and 500 matched healthy participants are selected as case and control groups, and randomized into discovery and validation sets to discove
Externí odkaz:
https://doaj.org/article/7ad08c3aa8de4ae8acc75cb7cf46b058
Publikováno v:
Journal of Proteome Research; 8/2/2024, Vol. 23 Issue 8, p3076-3087, 12p
Autor:
Fujian Zheng, Lei You, Wangshu Qin, Runze Ouyang, Wangjie Lv, Lei Guo, Xin Lu, Enyou Li, Xinjie Zhao, Guowang Xu
Publikováno v:
Analytical Chemistry. 94:8561-8569
Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) is the most popular platform for untargeted metabolomics studies, but compound annotation is a challenge. In this work, we developed a new LC-HRMS data-targeted extraction method calle
Autor:
Fujian Zheng, Xinyu Liu, Guowang Xu, Xiaoshan Sun, Xin Lu, Tianrun Xu, Chunxiu Hu, Hang Li, Lichao Wang, Xiaojun Peng, Wangjie Lv
Publikováno v:
Analytical Chemistry. 93:10528-10537
Direct-infusion nanoelectrospray ionization high-resolution mass spectrometry (DI-nESI-HRMS) is an alternative approach to chromatography-MS-based techniques for nontargeted metabolomics, offering a high sample throughout. However, its annotation acc
Publikováno v:
Analytical Chemistry. 92:7657-7665
The specific interactions between protein and metabolites (PMIs) are closely related to many cellular processes and play a vital role in signal transduction and regulating material and energy metabolism. However, most of the available analytical stra
Publikováno v:
Analytical Chemistry. 92:6043-6050
Metabolite and lipid profilings usually need two liquid chromatography-mass spectrometry (LC-MS) methods because of a great polarity difference. A pseudotargeted metabolomics method as a novel emerging approach can integrate the advantages of nontarg
Autor:
Wangjie Lv, Zhongda Zeng, Yuqing Zhang, Qingqing Wang, Lichao Wang, Zhaoxuan Zhang, Xianzhe Shi, Xinjie Zhao, Guowang Xu
Publikováno v:
Analytica chimica acta. 1215
Metabolomics-based precision medicine is facing several obstacles including cross-platform data comparison issue and the lack of metabolome benchmark values of healthy population, one of main reasons is the shortage of comprehensive metabolome quanti
Autor:
Xinjie Zhao, Rainer Lehmann, Yinan Zhang, Xinyu Liu, Xin Lu, Congrong Wang, Fujian Zheng, Lichao Wang, Xiaojun Peng, Guowang Xu, Qingqing Wang, Wangjie Lv, Tangchun Wu, Yang Ouyang, Weiping Jia, Gaokun Qiu
Publikováno v:
Journal of proteome research. 20(1)
Large-scale population screenings are not feasible by applying laborious oral glucose tolerance tests, but using fasting blood glucose (FPG) and glycated hemoglobin (HbA1c), a considerable number of diagnoses are missed. A novel marker is urgently ne
Autor:
Tianrun Xu, Yunlong Xia, Xinjie Zhao, Chunxiu Hu, Yuqing Zhang, Guowang Xu, Rongfeng Zhang, Xinyu Liu, Wangjie Lv, Yunpeng Xie
Publikováno v:
Journal of Chromatography A. 1651:462271
Successful applications of lipidomics in clinic need study large-scale samples, and the bottlenecks are in throughput and robustness of the lipid analytical method. Here, we report an untargeted lipidomics method by combining high throughput pretreat
Publikováno v:
Nature protocols. 15(8)
Untargeted methods are typically used in the detection and discovery of small organic compounds in metabolomics research, and ultra-high-performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) is one of the most commonly used