Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wanghai Zhang"'
Autor:
Charles A. Fox, Lisa M. Sapinoso, Hong Zhang, Wanghai Zhang, Howard L. McLeod, Gina R. Petroni, Tarun Mullick, Christopher A. Moskaluk, Henry F. Frierson, Garret M. Hampton, Steven M. Powell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 4, Pp 407-416 (2005)
Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare molecular signatures of normal esophagus and stomach
Externí odkaz:
https://doaj.org/article/5403deea7e904aeaa8eafff5a39a4e53
Autor:
Rajagopalan Sridhar, Edward Lee, Liang Shan, Renshu Zhang, Paul C. Wang, Wanghai Zhang, Elizabeth G. Snyderwine
Publikováno v:
Analytical Biochemistry. 382:122-128
We have developed an image-based technique for signal pathway analysis, target validation, and compound screening related to mammary epithelial cell differentiation. This technique used the advantages of optical imaging and the HC11-Lux model system.
Autor:
Ryan Miller, Wanghai Zhang, Vicky Holtschlag, Howard L. McLeod, Mark A. Watson, Jinsheng Yu, Mala Sharma
Publikováno v:
Pharmacogenomics. 9:1459-1466
Background: Archived formalin-fixed, paraffin-embedded specimens represent an important resource for pharmacogenomic analysis in retrospective clinical studies but the quality of results from formalin-fixed, paraffin-embedded samples is of concern du
Autor:
J Duncan, Wanghai Zhang, William D. Shannon, Rik J. Scheper, George L. Scheffer, Howard L. McLeod
Publikováno v:
The Journal of Pathology. 209:213-219
Current clinicopathological staging systems have the advantage of standardized criteria for assessing tumour stage, and a relationship between advancing tumour stage and poor prognosis has been established for most cancers. However, these tools have
Publikováno v:
American Journal of Clinical Pathology. 124:11-19
We immunohistochemically examined 75 human colorectal neoplasms (adenoma, 27; adenocarcinoma, 24; neuroendocrine carcinoma, 24) for the expression of activator protein (AP)-1 family proteins. Nuclear and cytoplasmic expression levels of c-Jun and Fra
Autor:
Lisa M. Sapinoso, Wanghai Zhang, Christopher A. Moskaluk, Gina R. Petroni, Steven M. Powell, Garret M. Hampton, Charles A. Fox, Howard L. McLeod, Hong Zhang, Henry F. Frierson, Tarun Mullick
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 4, Pp 407-416 (2005)
Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare molecular signatures of normal esophagus and stomach
Autor:
Margaret K. Ma, Weiying Hou, James W Watters, Howard L. McLeod, Wanghai Zhang, Melissa A. Meucci
Publikováno v:
Pharmacogenetics. 14:247-254
Although the mouse has great potential for pharmacogenomic discovery, little is known about variation in drug response or genetic variation in pharmacologically relevant genes between inbred mouse strains. We therefore assessed variation in gene sequ
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 10:374-380
Carboxylesterases play an important role in the hydrolytic biotransformation of a number of structurally diverse endogenous compounds and medications. Several distinct carboxylesterase isoforms have been described in human liver, brain, and placenta.
Autor:
Wanghai Zhang, Rainer Brachmann, Jue Zeng, Chris Papageorgio, Howard L. McLeod, Robert Culverhouse
The tumor suppressor protein p53 is a transcription factor that is frequently mutated in human cancers. In response to DNA damage, unmutated or wild-type (wt) p53 protein is stabilized and activated by post-transcriptional modifications that enable i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfea7e79f35608e2809ca0cfd2bc15c0
Autor:
Paul J. Goodfellow, Mary Ann Mallon, Wanghai Zhang, Robert R. Freimuth, Sharon Marsh, Howard L. McLeod, Mark A. Watson, Jinsheng Yu
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(17)
Background: The ability to maintain DNA integrity is a critical cellular function. DNA repair is conducted by distinct pathways of genes, many of which are thought to be altered in colorectal cancer. However, there has been little characterization of