Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Wangbin Wu"'
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Akademický článek
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior
Autor: Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Siddhartha Kumar, Wangbin Wu, Ben Nolan, Samikshan Dutta, Matthew D. Storck, Micah Schott, Jane L. Meza, Subodh M. Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Amarnath Natarajan, Kaustubh Datta, Vimla Band, Hamid Band
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to tumor progression in PC could ope
Externí odkaz: https://doaj.org/article/5e1271695c79456bb92777ad45c70f97
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3
Thiol-Reactive Arylsulfonate Masks for Phenolate Donors in Antiproliferative Iron Prochelators
Autor: Wangbin Wu, Yu-Shien Sung, Elisa Tomat
Publikováno v: Inorganic Chemistry. 61:19974-19982
Tridentate thiosemicarbazones, among several families of iron chelators, have shown promising results in anticancer drug discovery because they target the increased need for iron that characterizes malignant cells. Prochelation strategies, in which t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a4dcb0980acad0a34b3e03bfcbb705
https://doi.org/10.1021/acs.inorgchem.2c03250
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4
Asymmetric Baeyer–Villiger oxidation: classical and parallel kinetic resolution of 3-substituted cyclohexanones and desymmetrization of meso-disubstituted cycloketones
Autor: Zhishan Su, Weidi Cao, Xiaohua Liu, Linfeng Hu, Wangbin Wu, Xiaoming Feng
Publikováno v: Chemical Science. 10:7003-7008
Regioselectivity is a crucial issue in Baeyer-Villiger (BV) oxidation. To date, few reports have addressed asymmetric BV oxidation of 3-substituted cycloketones due to the high difficulty of controlling regio- and stereoselectivity. Herein, we report
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5deddc66cbfe73841fc6b2e1c676b155
https://doi.org/10.1039/c9sc01563a
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5
Albumin Conjugates of Thiosemicarbazone and Imidazole-2-thione Prochelators: Iron Coordination and Antiproliferative Activity
Autor: Yu Shien Sung, Wangbin Wu, Elisa Tomat, Michael T. Marty, Megan A. Ewbank, Rachel D. Utterback
Publikováno v: ChemMedChem
The central role of iron in tumor progression and metastasis motivates the development of iron-binding approaches in cancer chemotherapy. Disulfide-based prochelators are reductively activated upon cellular uptake to liberate thiol chelators responsi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e44b00058ca27631b85a1cfcef5f2c
https://pubmed.ncbi.nlm.nih.gov/33974730
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7
Catalytic asymmetric Meerwein–Ponndorf–Verley reduction of glyoxylates induced by a chiral N,N′-dioxide/Y(OTf)3complex
Autor: Xiaohua Liu, Yuheng Zhang, Baiwei Ma, Jie Ji, Xiaoming Feng, Wangbin Wu, Sijia Zou, Lili Lin
Publikováno v: Chemical Communications. 53:3232-3235
An asymmetric Meerwein–Ponndorf–Verley (MPV) reduction of glyoxylates was for the first time accomplished via an N,N′-dioxide/Y(OTf)3 complex with aluminium alkoxide and molecular sieves (MSs) as crucial additives. A variety of optically active
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3f8f54b12e455427c21051289d39089
https://doi.org/10.1039/c7cc00273d
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8
Enantioselective Radical-Polar Crossover Reactions of Indanonecarboxamides with Alkenes
Autor: Xi Xu, Han Yu, Weidi Cao, Wangbin Wu, Xiying Zhang, Xiaohua Liu, Xiaoming Feng
Publikováno v: Angewandte Chemie (International ed. in English). 59(12)
Highly efficient asymmetric intermolecular radical-polar crossover reactions were realized by combining a chiral N,N'-dioxide/NiII complex catalyst with Ag2 O under mild reaction conditions. Various terminal alkenes and indanonecarboxamides/esters un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efbaec07bbcdfdeed5a309999918977
https://pubmed.ncbi.nlm.nih.gov/31930609
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9
Asymmetric Baeyer-Villiger oxidation: classical and parallel kinetic resolution of 3-substituted cyclohexanones and desymmetrization of
Autor: Wangbin, Wu, Weidi, Cao, Linfeng, Hu, Zhishan, Su, Xiaohua, Liu, Xiaoming, Feng
Publikováno v: Chemical Science
Classical kinetic resolution, parallel kinetic resolution and desymmetrization were achieved by asymmetric BV oxidation of 3-substituted and meso-disubstituted cycloketones.
Regioselectivity is a crucial issue in Baeyer–Villiger (BV) oxidation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23b04f2baee03f0e2c7e58fe585b9d99
https://pubmed.ncbi.nlm.nih.gov/31588267
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10
Catalytic Asymmetric Construction of β-Azido Amides and Esters via Haloazidation
Autor: Pengfei Zhou, Chaoran Xu, Xiaoming Feng, Xiaohua Liu, Wangbin Wu
Publikováno v: Organic letters. 21(4)
A catalytic regio- and enantioselective haloazidation reaction with a chiral iron(II) complex catalyst under mild reaction conditions was reported. By this approach, the stereoselective α-halo-β-azido difunctionalization of both α,β-unsaturated a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddd2db753f2cd2972c896d0a8553662
https://pubmed.ncbi.nlm.nih.gov/30693781
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