Výsledky vyhledávání - "Wang-gang Zhang"

Akademický článek

Five-year remission without disease progression in a patient with relapsed/refractory multiple myeloma with extramedullary disease treated with LCAR-B38M chimeric antigen receptor T cells in the LEGEND-2 study: a case report

Publikováno v: Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-8 (2022)

Abstract Background Multiple myeloma remains incurable despite treatment advancements over the last 20 years. LCAR-B38M Cells in Treating Relapsed/Refractory Multiple Myeloma was a phase 1, first-in-human, investigator-initiated study in relapsed/ref

Externí odkaz: https://doaj.org/article/c9b293fef2f645698bfc3549329d7fc0

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Akademický článek

Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2)

Publikováno v: Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-12 (2022)

Abstract Background LCAR-B38M is a chimeric antigen receptor T cell product with two binding domains targeting B cell maturation antigen. Our previous reports showed a remarkable efficacy of LCAR-B38M in patients with relapsed/refractory multiple mye

Externí odkaz: https://doaj.org/article/680bd4fe1f994d6db669554110364f34

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Akademický článek

Improvement of stretch formability and weakening the basal texture of Mg alloy by corrugated wide limit alignment and annealing process

Autor: Hui-Hu Lu, Li Lu, Wang-Gang Zhang, Zhen-Guang Liu, Wei Liang

Publikováno v: Journal of Materials Research and Technology, Vol 17, Iss , Pp 2495-2504 (2022)

In this paper, a process of corrugated wide limit alignment (CWLA) was used to improve the stretch formability of large-dimension AZ31 Mg alloy sheets by inducing tensile twins. The effects of {10 1¯ 2} tensile twins on microstructure evolution, mec

Externí odkaz: https://doaj.org/article/dd0c2e3dbf42413691eb1932c1084cda

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Akademický článek

Microstructural evolution and mechanical properties of V-containing medium-Mn steel manufactured via cold rolling and intercritical annealing

Autor: Shao-bin Bai, Wen-tao Xiao, Wei-qiang Niu, Yi-de Wang, Da-zhao Li, Wang-gang Zhang, Quan-xin Shi, Wei Liang

Publikováno v: Journal of Materials Research and Technology, Vol 14, Iss , Pp 1504-1517 (2021)

V was added into a cold-rolled medium-Mn steel for optimizing comprehensive mechanical properties by the V-carbide precipitation. After annealing, the V-carbide particles in austenite grains easily coarsen than that in ferrite. The contributed yield

Externí odkaz: https://doaj.org/article/f9a30540559a481193e0b08dac48cf38

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Akademický článek

A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma

Publikováno v: Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-8 (2018)

Abstract Background Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directed against 2 distinct

Externí odkaz: https://doaj.org/article/465fd456636849ce93bd874e19984b0a

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Akademický článek

Iodine-125 Brachytherapy Prophylaxis after Radiofrequency Ablation Cannot Benefit Patients in High Risk of Locoregional Hepatocellular Carcinoma Recurrence

Autor: Jian-Fei Tu, Ya-Hui Ding, Li Chen, Xi-Hui Ying, Deng-Ke Zhang, Fa-Zong Wu, Zhong-Wei Zhao, Jian-Song Ji, Wang-Gang Zhang, Hai Zou

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)

Abstract This study evaluated if iodine-125 brachytherapy prophylaxis after radiofrequency ablation (RFA) prolongs time to recurrence (TTR) and overall survival (OS) of patients in high risk of locoregional hepatocellular carcinoma (HCC) recurrence.

Externí odkaz: https://doaj.org/article/b4b0f42caab1422991ab01580082beb5

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Akademický článek

Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia

Publikováno v: EBioMedicine, Vol 8, Iss C, Pp 173-183 (2016)

Genomic landscapes of 92 adult and 111 pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL) were investigated using next-generation sequencing and copy number alteration analysis. Recurrent gene mutations and fusions were tested in an

Externí odkaz: https://doaj.org/article/13f2b015a60a4c56b66f1473c018a978

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