Zobrazeno 1 - 10
of 1 036
pro vyhledávání: '"Wang-Gillam A."'
Autor:
Xiuli Zhang, S. Peter Goedegebuure, Michael Y. Chen, Rashmi Mishra, Felicia Zhang, Yik Yeung Yu, Kartik Singhal, Lijin Li, Feng Gao, Nancy B. Myers, Tammi Vickery, Jasreet Hundal, Michael D. McLellan, Mark A. Sturmoski, Samuel W. Kim, Ina Chen, Jesse T. Davidson, Narendra V. Sankpal, Stephanie Myles, Rama Suresh, Cynthia X. Ma, Ademuyiwa Foluso, Andrea Wang-Gillam, Sherri Davies, Ian S. Hagemann, Elaine R. Mardis, Obi Griffith, Malachi Griffith, Christopher A. Miller, Ted H. Hansen, Timothy P. Fleming, Robert D. Schreiber, William E. Gillanders
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Neoantigen vaccines can induce or enhance highly specific antitumor immune responses with minimal risk of autoimmunity. We have developed a neoantigen DNA vaccine platform capable of efficiently presenting both HLA class I and II
Externí odkaz:
https://doaj.org/article/361f87535f3347da8e2cfda87d75ab59
Autor:
Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Kiran Zahra, Vikas Somani, Iftikhar Ali Khawar, Hung-Po Chen, Paarth B. Dodhiawala, Lin Li, Yutong Geng, Chia-Kuei Mo, Jay Mahsl, Li Ding, Ramaswamy Govindan, Sherri Davies, Jacqueline Mudd, William G. Hawkins, Ryan C. Fields, David G. DeNardo, Deborah Knoerzer, Jason M. Held, Patrick M. Grierson, Andrea Wang-Gillam, Marianna B. Ruzinova, Kian-Huat Lim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Targeting the mitogen-activated protein kinase (MAPK) cascade in pancreatic ductal adenocarcinoma (PDAC) remains clinically unsuccessful. We aim to develop a MAPK inhibitor-based therapeutic combination with strong preclinical efficacy. Util
Externí odkaz:
https://doaj.org/article/fb6737dcacf54c9e884795a4aec86099
Autor:
Wattenberg, Max M., Colby, Sarah, Garrido-Laguna, Ignacio, Xue, Yuqing, Chang, Renee, Delman, Devora, Lee, Jesse, Affolter, Kajsa, Mulvihill, Sean J., Beg, M. Shaalan, Wang-Gillam, Andrea, Wade, James Lloyd, III, Guthrie, Katherine A., Chiorean, E. Gabriela, Ahmad, Syed A., Lowy, Andrew M., Philip, Philip Agop, Sohal, Davendra P.S., Beatty, Gregory L.
Publikováno v:
In Gastroenterology June 2024 166(6):1114-1129
Autor:
Sohal, Davendra P.S., Boutin, Robert D., Lenchik, Leon, Kim, Jiyoon, Beg, M. Shaalan, Wang-Gillam, Andrea, Wade, James Lloyd, III, Guthrie, Katherine A., Chiorean, E. Gabriela, Ahmad, Syed A., Lowy, Andrew M., Philip, Philip Agop, Chang, Victor Tsu-Shih
Publikováno v:
In Journal of Gastrointestinal Surgery March 2024 28(3):232-235
Autor:
Afsaneh Barzi, Caroline M. Weipert, Carin R. Espenschied, Victoria M. Raymond, Andrea Wang-Gillam, Mohammad Amin Nezami, Eva J. Gordon, Daruka Mahadevan, Kabir Mody
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeDespite accumulating data regarding the genomic landscape of pancreatic ductal adenocarcinoma (PDAC), olaparib is the only biomarker-driven FDA-approved targeted therapy with a PDAC-specific approval. Treating ERBB2(HER2)-amplified PDAC with a
Externí odkaz:
https://doaj.org/article/e7677069cab2423eb1241b17d63bdd06
Autor:
Kevin Conlon, Robert Wesolowski, Douglas G McNeel, John A Thompson, Rom Leidner, Andrea Wang-Gillam, Sumati Gupta, Nancy Lewis, George N Pavlakis, Lang Ho Lee, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Jessica A O’Keeffe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Preclinically, interleukin-15 (IL-15) monotherapy promotes antitumor immune responses, which are enhanced when IL-15 is used in combination with immune checkpoint inhibitors (ICIs). This first-in-human study investigated NIZ985, a recombin
Externí odkaz:
https://doaj.org/article/2886323ab834455e8737872e76203efc
Autor:
Kim, Hyun *, Olsen, Jeffrey R., Green, Olga L. *, Chin, Re-I *, Hawkins, William G., Fields, Ryan C., Hammill, Chet, Doyle, Majella B., Chapman, William, Suresh, Rama, Tan, Benjamin, Pedersen, Katrina, Jansen, Brandi *, DeWees, Todd A., Lu, Esther, Henke, Lauren E. *, Badiyan, Shahed *, Parikh, Parag J., Roach, Michael C., Wang-Gillam, Andrea, Lim, Kian-Huat
Publikováno v:
In International Journal of Radiation Oncology, Biology, Physics 1 January 2023 115(1):214-223
Autor:
Marcus S. Noel, Semmie Kim, Marion L. Hartley, Steve Wong, Vincent J. Picozzi, Harry Staszewski, Dae Won Kim, Jan M. Van Tornout, Philip Agop Philip, Vincent Chung, Allyson J. Ocean, Andrea Wang‐Gillam
Publikováno v:
Cancer Medicine, Vol 11, Iss 22, Pp 4169-4181 (2022)
Abstract Background This trial explores SM‐88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) Methods Forty‐nine patients were randomized to daily 460 or 920 mg oral SM‐88
Externí odkaz:
https://doaj.org/article/566d5c8953714e0c95e07051f157b1d7
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