Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Wang Shick Ryu"'
Publikováno v:
BioTechniques, Vol 59, Iss 5, Pp 287-293 (2015)
After encapsidation, where pregenomic RNA (pgRNA) is packaged into viral nucleocapsids, hepatitis B virus (HBV) uses the pgRNA as a template to replicate its DNA genome by reverse transcription. To date, there are only two encapsidation detection met
Externí odkaz:
https://doaj.org/article/bf63f10c92c34c44af9a4a84d3cf0f98
Publikováno v:
BioTechniques, Vol 36, Iss 3, Pp 398-400 (2004)
Externí odkaz:
https://doaj.org/article/71800b8ee4de4a0297ca6ea972a558c2
Publikováno v:
Journal of Medical Virology
Drug repositioning represents an effective way to control the current COVID‐19 pandemic. Previously, we identified 24 FDA‐approved drugs which exhibited substantial antiviral effect against severe acute respiratory syndrome coronavirus 2 in Vero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47629a47e7279abb0268684e93317a56
https://pubmed.ncbi.nlm.nih.gov/32767684
https://pubmed.ncbi.nlm.nih.gov/32767684
Drug repositioning represents an effective way to control the current COVID-19 pandemic. Previously, we identified 24 FDA-approved drugs which exhibited substantial antiviral effect against SARS-CoV-2 in Vero cells. Since antiviral efficacy could be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353651950bb07bcb8c02c9d34a0feca9
https://doi.org/10.1101/2020.05.12.090035
https://doi.org/10.1101/2020.05.12.090035
Autor:
Haifeng Wang, Wang-Shick Ryu
Publikováno v:
PLoS Pathogens, Vol 6, Iss 7, p e1000986 (2010)
Viral infection leads to induction of pattern-recognition receptor signaling, which leads to interferon regulatory factor (IRF) activation and ultimately interferon (IFN) production. To establish infection, many viruses have strategies to evade the i
Externí odkaz:
https://doaj.org/article/04d6c591600546bd83312abf26306c88
Autor:
Wang-Shick Ryu, Sanghyun Park, Jonathan Cechetto, Tae-Hee Kim, Yoojin Cho, Seung Kew Yoon, Eunji Jo, Soonju Park, Alexander König, Marc P. Windisch, Dong Kyun Ryu
Publikováno v:
Antiviral research. 175
Currently, therapies to treat chronic hepatitis B (CHB) infection are based on the use of interferon-α or nucleos(t)ide analogs (NAs) to prevent viral DNA synthesis by inhibiting the reverse transcriptase activity of the hepatitis B virus (HBV) poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e0a6907cb2756a9dcc94ed5a7cf6be
https://pubmed.ncbi.nlm.nih.gov/31940474
https://pubmed.ncbi.nlm.nih.gov/31940474
Publikováno v:
Antiviral research. 163
Despite the utmost importance of cccDNA in HBV biology, the mechanism by which cccDNA synthesis is regulated is not completely understood. Here we explored HepG2-NTCP cell line and performed a time-course HBV infection experiment (up to 30 days) to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bc13918c0ac604f946b18749611837
https://pubmed.ncbi.nlm.nih.gov/30639437
https://pubmed.ncbi.nlm.nih.gov/30639437
Autor:
Jung-Hee Kim, Marc P. Windisch, Soonju Park, Wang-Shick Ryu, Jun Yong Park, Seung Kew Yoon, Wolfram H. Gerlich, Xiyong Song, Alexander König, Thoa Thi Than, David Shum, Sang Hoon Ahn, Xinghong Dai, Kwang Hyub Han, Eunji Jo, Xiaoxuan Qi, Hyun Kim, Kyu Ho Paul Park, Jaewon Yang
Publikováno v:
Journal of hepatology. 71(2)
Background & Aims As hepatitis B virus (HBV) spreads through the infected liver it is simultaneously secreted into the blood. HBV-susceptible in vitro infection models do not efficiently amplify viral progeny or support cell-to-cell spread. We sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb73c6df31c6520d875dc57c3a5dbeeb
https://pubmed.ncbi.nlm.nih.gov/31077792
https://pubmed.ncbi.nlm.nih.gov/31077792
Autor:
Ke Zhang, Karin Wisskirchen, Anindita Chakraborty, Theresa Asen, Wen Min Chou, Wang-Shick Ryu, Jane A. McKeating, Julia Hasreiter, Ulrike Protzer, Romina Bester, Daniela Stadler, Chunkyu Ko, Jochen M. Wettengel
Publikováno v:
Journal of Hepatology
J Hepatol
J. Hepatol. 69, 1231-1241 (2018)
J Hepatol
J. Hepatol. 69, 1231-1241 (2018)
Background & Aims: Several steps in the HBV life cycle remain obscure because of a lack of robust in vitro infection models. These steps include particle entry, formation and maintenance of covalently closed circular (ccc) DNA, kinetics of gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1bca585829b1a1d5ea1840b9cb9484
https://doi.org/10.1016/j.jhep.2018.08.012
https://doi.org/10.1016/j.jhep.2018.08.012
Publikováno v:
Antiviral Research
Highlights • Activation of RNase L inhibits HBV replication in infected and transfected hepatoma cells. • Antiviral activity of RNase L depends on its ribonuclease function. • OAS2 and OAS3 but not OAS1 are involved in RNase L activation in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34ee22d99c9314636756eb32aa35e96
https://doi.org/10.1016/j.antiviral.2014.01.021
https://doi.org/10.1016/j.antiviral.2014.01.021