Knockdown of NUPR1 inhibits angiogenesis in lung cancer through IRE1/XBP1 and PERK/eIF2α/ATF4 signaling pathways

Autor: Wang Lihuai, Wen Jing, Sun Yinhui, Yang Xiao, Ma Yi, Tian Xuefei

Publikováno v: Open Medicine, Vol 18, Iss 1, Pp 1367-80 (2023)

The stress response molecule nuclear protein‑1 (NUPR1) is essential for the growth of multiple types of human malignant tumor cells. However, the significance of NUPR1 in lung cancer is still not entirely elucidated. Therefore, this study is aimed

Externí odkaz: https://doaj.org/article/fe2e05a2021c418fa447beb12ac8cc79

Nuclear protein 1 promotes unfolded protein response during endoplasmic reticulum stress, and alleviates apoptosis induced by cisplatin in non-small cell lung cancer cells

Autor: Sun, Yinhui, Wang, Lihuai, Deng, Changqing, Liu, Hua, Guo, Zhongcong, Chang, Zelin, Mo, Jianxiong

Publikováno v: Tropical Journal of Pharmaceutical Research; Vol. 20 No. 3 (2021); 519-524

Purpose: To investigate the role of nuclear protein 1 (NUPR1) in the drug resistance of non-small cell lung cancer (NSCLC) and its regulatory mechanisms. Methods: Quantitative polymerase chain reaction (qPCR) and immunoblot assays were conducted to d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10075fe99336f6591c36021ecdd696e
https://doi.org/10.4314/tjpr.v20i3.11

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Clinical effect of cold and heat ablation on patients with advanced lung cancer and its influence on immune function.

Autor: Cheng R; Department of Vascular and Neoplastic Intervention, The First Affiliated Hospital of Hunan University of Chinese Medicine No. 95, Middle Shaoshan Road, Changsha 410007, Hunan, China., Li Y; Department of Vascular and Neoplastic Intervention, The First Affiliated Hospital of Hunan University of Chinese Medicine No. 95, Middle Shaoshan Road, Changsha 410007, Hunan, China., Su L; Department of Vascular and Neoplastic Intervention, The First Affiliated Hospital of Hunan University of Chinese Medicine No. 95, Middle Shaoshan Road, Changsha 410007, Hunan, China., Wang L; Department of Oncology, The First Affiliated Hospital of Hunan University of Chinese Medicine No. 95, Middle Shaoshan Road, Changsha 410007, Hunan, China., Cao Y; Department of Vascular and Neoplastic Intervention, The First Affiliated Hospital of Hunan University of Chinese Medicine No. 95, Middle Shaoshan Road, Changsha 410007, Hunan, China.

Publikováno v: American journal of translational research [Am J Transl Res] 2023 Apr 15; Vol. 15 (4), pp. 2939-2948. Date of Electronic Publication: 2023 Apr 15 (Print Publication: 2023).