GPx1-ERK1/2-CREB pathway regulates the distinct vulnerability of hippocampal neurons to oxidative stress via modulating mitochondrial dynamics following status epilepticus

Autor: Kim, Ji-Eun, Lee, Duk-Shin, Wang, Su Hyeon, Kim, Tae-Hyun, Kang, Tae-Cheon

Publikováno v: In Neuropharmacology 1 December 2024 260

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Neuronal PLPP/CIN exaggerates the immune response of hippocampal microglia to LPS challenge dependent on PAK1-NF-κB-COX-2 signaling pathway.

Autor: Kim JE; Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon 24252, South Korea., Wang SH; Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon 24252, South Korea., Lee DS; Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon 24252, South Korea., Kim TH; Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon 24252, South Korea., Kang TC; Department of Anatomy and Neurobiology, Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon 24252, South Korea. Electronic address: tckang@hallym.ac.kr.

Publikováno v: Brain research [Brain Res] 2024 Nov 22; Vol. 1849, pp. 149345. Date of Electronic Publication: 2024 Nov 22.