Výsledky vyhledávání

Dissertation/ Thesis

Differential Regulation of Interleukin-12 (IL-12)/IL-23 by Tim-3 Drives TH17 Cell Development During Hepatitis C Virus Infection

Autor: Wang, Jia M., Shi, Lei, Ma, Cheng J., Ji, Xiao J., Ying, Ruo S., Wu, Xiao Y., Wang, Ke S., Li, Guangyu, Moorman, Jonathan P., Yao, Zhi Q.

Publikováno v: ETSU Faculty Works.

Cytokine production by innate immunity is critical for shaping the adaptive immunity through regulation of T cell differentiation. In this report, we studied T cell immunoglobulin mucin domain protein 3 (Tim-3) expression on monocytes and its regulat

Externí odkaz: https://dc.etsu.edu/etsu-works/14303

Zobrazit plný text záznamu

Dissertation/ Thesis

Tim-3 Pathway Controls Regulatory and Effector T Cell Balance During Hepatitis C Virus Infection

Autor: Moorman, Jonathan P., Wang, Jia M., Zhang, Ying, Ji, Xiao J., Ma, Cheng J., Wu, Xiao Y., Jia, Zhan S., Wang, Ke S., Yao, Zhi Q.

Publikováno v: ETSU Faculty Works.

Hepatitis C virus (HCV) is remarkable at disrupting human immunity to establish chronic infection. Upregulation of inhibitory signaling pathways (such as T cell Ig and mucin domain protein-3 [Tim-3]) and accumulation of regulatory T cells (Tregs) pla

Externí odkaz: https://dc.etsu.edu/etsu-works/16021

Zobrazit plný text záznamu