Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.

Autor: Rollema, H, Shrikhande, A, Ward, KM, Tingley III, FD, Coe, JW, O'Neill, BT, Tseng, E, Wang, EQ, Mather, RJ, Hurst, RS, Williams, KE, De Vries, M, Cremers, T, Bertrand, S, Bertrand, D, Ward, K M, Tingley, F D 3rd, Coe, J W, O'Neill, B T, Wang, E Q

Publikováno v: British Journal of Pharmacology; May2010, Vol. 160 Issue 2, p334-345, 12p

Perturbation and nonlinear dynamic analysis of acoustic phonatory signal in Parkinsonian patients receiving deep brain stimulation.

Autor: Lee VS (AUTHOR), Zhou XP (AUTHOR), Rahn DA III (AUTHOR), Wang EQ (AUTHOR), Jiang JJ (AUTHOR)

Publikováno v: Journal of Communication Disorders. Nov2008, Vol. 41 Issue 6, p485-500. 16p.

Population PK/PD modeling of low-density lipoprotein cholesterol response in hypercholesterolemic participants following administration of bococizumab, a potent anti-PCSK9 monoclonal antibody.

Autor: Wang EQ; Clinical Pharmacology & Bioanalytics, Pfizer Inc., New York, New York, USA., Kaila N; Clinical Pharmacology & Bioanalytics, Pfizer Inc., Groton, Connecticut, USA., Plowchalk D; Clinical Pharmacology & Bioanalytics, Pfizer Inc., Groton, Connecticut, USA., Gibiansky L; QuantPharm LLC, North, Maryland, USA., Yunis C; Global Product Development, Pfizer Inc., Florida, USA., Sweeney K; Clinical Pharmacology & Bioanalytics, Pfizer Inc., Groton, Connecticut, USA.

Publikováno v: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Dec; Vol. 12 (12), pp. 2013-2026. Date of Electronic Publication: 2023 Nov 22.

Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial.

Autor: Chen HS; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Cui Y; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Zhou ZH; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Zhang H; Department of Neurology, Liaoning Health Industry Group Fukuang General Hospital, Fushun, China., Wang LX; Department of Neurology, Tieling Central Hospital, Tieling, China., Wang WZ; Department of Neurology, Dandong Central Hospital, Dandong, China., Shen LY; Department of Neurology, Tieling County Central Hospital, Tieling, China., Guo LY; Department of Neurology, Fushun Second Hospital, Fushun, China., Wang EQ; Department of Neurology, The Fuqing Affiliated Hospital of Fujian Medical University, Fuqing, China., Wang RX; Department of Neurology, The Tianjin Beichen Traditional Chinese Medicine Hospital, Tianjin, China., Han J; Department of Neurology, Panjin Central Hospital, Panjin, China., Dong YL; Department of Neurology, Chaoyang Second Hospital, Chaoyang, China., Li J; Department of Neurology, Donggang Central Hospital, Donggang, China., Lin YZ; Department of Neurology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China., Yang QC; Department of Neurology, Anyang People's Hospital, Anyang, China., Zhang L; Department of Neurology, Suizhong Central Hospital, Suizhong, China., Li JY; Department of Neurology, Chinese People's Liberation Army 967 Hospital, Dalian, China., Wang J; Department of Neurology, Huludao Central Hospital, Huludao, China., Xia L; Department of Neurology, Zhoukou Central Hospital, Zhoukou, China., Ma GB; Department of Neurology, Haicheng Traditional Chinese Medicine Hospital, Haicheng, China., Lu J; Department of Neurology, The Dalinghe Affiliated Hospital of Jinzhou Medical University, Jinzhou, China., Jiang CH; Department of Neurology, Lvshunkou Traditional Chinese Medicine Hospital, Lvshunkou, China., Huang SM; Department of Neurology, Dawa District People's Hospital, Panjin, China., Wan LS; Department of Neurology, Dandong First Hospital, Dandong, China., Piao XY; Department of Neurology, The Zhongshan Affiliated Hospital of Dalian University, Dalian, China., Li Z; Department of Neurology, Panjin Central Hospital, Panjin, China., Li YS; Department of Neurology, Army Hospital of Northern Theatre Command, Shenyang, China., Yang KH; Department of Neurology, Liaoyang Second People's Hospital, Liaoyang, China., Wang DL; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Nguyen TN; Neurology, Radiology, Boston Medical Center, Boston, Massachusetts.

Publikováno v: JAMA [JAMA] 2023 Jun 27; Vol. 329 (24), pp. 2135-2144.

Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial.

Autor: Chen HS; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Cui Y; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Zhou ZH; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Dai YJ; Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China., Li GH; Department of Neurology, Liaoning Health Industry Group Fukuang General Hospital, Fushun, China., Peng ZL; Department of Neurology, The Affiliated Nanshi Hospital of Henan University, Nanyang, China., Zhang Y; Department of Neurology, Tieling County Central Hospital, Tieling, China., Liu XD; Department of Neurology, Tonghua Vascular Disease Hospital, Tonghua, China., Yuan ZM; Department of Neurology, Tonghua Vascular Disease Hospital, Tonghua, China., Jiang CH; Department of Neurology, Lvshunkou Traditional Chinese Medicine Hospital, Dalian, China., Yang QC; Department of Neurology, Anyang People's Hospital, Anyang, China., Duan YJ; Department of Neurology, Liaoning Health Industry Group Fuxinkuang General Hospital, Fuxin, China., Ma GB; Department of Neurology, Haicheng Traditional Chinese Medicine Hospital, Haicheng, China., Zhao LW; Department of Neurology, Anshan Changda Hospital, Anshan, China., Wang RX; Department of Neurology, Tianjin Beichen Traditional Chinese Hospital, Tianjin, China., Sun YL; Department of Neurology, Panjin Central Hospital, Panjin, China., Shen L; Department of Neurology, Nanyang Central Hospital, Nanyang, China., Wang EQ; Department of Neurology, Fuqing Hospital, Fuqing, China., Wang LH; Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Feng YF; Department of Neurology, Huludao Second People's Hospital, Huludao, China., Wang FY; Department of Neurology, Liaocheng Brain Hospital, Liaocheng, China., Zou RL; Department of Neurology, Wafangdian Third Hospital, Dalian, China., Yang HP; Department of Neurology, Guangxi Zhuang Autonomous Region People's Hospital, Nanning, China., Wang K; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Wang DL; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Wang YL; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Publikováno v: JAMA [JAMA] 2023 Feb 28; Vol. 329 (8), pp. 640-650.