Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wandy, Chan"'
Autor:
Alexander Dashwood, Elizabeth Cheesman, Yee Weng Wong, Haris Haqqani, Nicole Beard, Karen Hay, Melanie Spratt, Wandy Chan, Peter Molenaar
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifica
Externí odkaz:
https://doaj.org/article/b72fc90c024c4b669e467a550e0991fe
Autor:
Saranya Hariharaputhiran, Yang Peng, Linh Ngo, Anna Ali, Sadia Hossain, Renuka Visvanathan, Robert Adams, Wandy Chan, Isuru Ranasinghe
Publikováno v:
European journal of heart failure. 24(9)
Contemporary long-term survival following a heart failure (HF) hospitalization is uncertain. We evaluated survival up to 10 years after a HF hospitalization using national data from Australia and New Zealand, identified predictors of survival, and es
Autor:
Maryam Khorramshahi Bayat, Linh Ngo, Andrew Mulligan, Wandy Chan, Scott McKenzie, Karen Hay, Isuru Ranasinghe
Publikováno v:
European heart journal. Quality of careclinical outcomes. 8(7)
Aims Urinary sodium concentration (UNa) is a simple test advocated to assess diuretics efficacy and predict outcomes in acute heart failure (AHF). We performed a systematic review and meta-analysis to examine the association of UNa with outcomes of A
Autor:
Louise E, See Hoe, Matthew A, Wells, Nicole, Bartnikowski, Nchafatso G, Obonyo, Jonathan E, Millar, Aimee, Khoo, Katrina K, Ki, Tristan, Shuker, Alessandro, Ferraioli, Sebastiano M, Colombo, Wandy, Chan, David C, McGiffin, Jacky Y, Suen, John F, Fraser
Publikováno v:
Transplantation. 104(11)
Despite advances in mechanical circulatory devices and pharmacologic therapies, heart transplantation (HTx) is the definitive and most effective therapy for an important proportion of qualifying patients with end-stage heart failure. However, the dem
Autor:
A. Mark Richards, W. Y. Wandy Chan, Chris Frampton, Ian Crozier, Christopher J. Charles, David L. Jardine, Richard W. Troughton
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 42:888-895
Summary Sympatholytic and vasodilator drugs have been of major therapeutic benefit in patients with heart failure (HF). Urocortin-2 (Ucn2) is a small corticotrophin-related peptide distributed throughout the cardiovascular system which inhibits cardi
Autor:
Dan Gutfinger, Neal L. Eigler, Michael Benser, Ian G. Crozier, Richard W. Troughton, Iain C. Melton, W.Y. Wandy Chan M.D., Andreas Blomqvist, Kjell Noren
Publikováno v:
Pacing and Clinical Electrophysiology. 37:810-819
Background We hypothesized that left atrial pressure (LAP) obtained by a permanent implantable sensor is sensitive to changes in cardiac resynchronization therapy (CRT) settings and could guide CRT optimization to improve the response rate. We invest
Publikováno v:
JACC: Heart Failure. 1:433-441
Objectives The purpose of this study is to investigate the effects of urocortin-2 as adjunct therapy in acute decompensated heart failure (ADHF). Background Urocortin-2 produced favorable integrated effects in experimental heart failure but there are
Autor:
W Y Wandy, Chan, Christopher M, Frampton, Ian G, Crozier, Richard W, Troughton, A Mark, Richards
Publikováno v:
JACC. Heart failure. 1(5)
The purpose of this study is to investigate the effects of urocortin-2 as adjunct therapy in acute decompensated heart failure (ADHF).Urocortin-2 produced favorable integrated effects in experimental heart failure but there are no equivalent human da
Autor:
W Y Wandy, Chan, Andreas, Blomqvist, Iain C, Melton, Kjell, Norén, Ian G, Crozier, Michael E, Benser, Neal L, Eigler, Dan, Gutfinger, Richard W, Troughton
Publikováno v:
Pacing and clinical electrophysiology : PACE. 37(7)
We hypothesized that left atrial pressure (LAP) obtained by a permanent implantable sensor is sensitive to changes in cardiac resynchronization therapy (CRT) settings and could guide CRT optimization to improve the response rate. We investigated the
Publikováno v:
The New Zealand medical journal. 123(1324)
Thrombolysis for normotensive patients with large clot burden pulmonary embolism remains debatable. We aim to document our current management of pulmonary embolism, examining determinants of therapy and outcomes.A retrospective chart-based review of