Tofacitinib inhibits the development of experimental autoimmune uveitis and reduces the proportions of Th1 but not of Th17 cells.

Autor: Bing SJ; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD., Lyu C; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China., Xu B; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD., Wandu WS; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD., Hinshaw SJ; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD., Furumoto Y; Translational Immunology Section, Office of Science and Technology, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD., Caspi RR; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD., Gadina M; Translational Immunology Section, Office of Science and Technology, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD., Gery I; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD.

Publikováno v: Molecular vision [Mol Vis] 2020 Sep 26; Vol. 26, pp. 641-651. Date of Electronic Publication: 2020 Sep 26 (Print Publication: 2020).

Unlike Th1/Th17 cells, Th2/Th9 cells selectively migrate to the limbus/conjunctiva and initiate an eosinophilic infiltration process.

Autor: Tan C; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Wandu WS; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., St Leger A; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Kielczewski J; Biological Imaging Core, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Wawrousek EF; Genetic Engineering Core, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Chan CC; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Gery I; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: geryi@nei.nih.gov.

Publikováno v: Experimental eye research [Exp Eye Res] 2018 Jan; Vol. 166, pp. 116-119. Date of Electronic Publication: 2017 Oct 24.

Cost-Effective Recruitment Strategies That Attract Underrepresented Minority Undergraduates Who Persist to STEM Doctorates.

Autor: Shadding CR; Washington University School of Medicine in St. Louis, MO, USA., Whittington D; Strategic Evaluations, Inc., Durham, NC, USA., Wallace LE; Washington University School of Medicine in St. Louis, MO, USA., Wandu WS; National Eye Institute, Bethesda, NIH, MD, USA., Wilson RK; Washington University School of Medicine in St. Louis, MO, USA.

Publikováno v: SAGE open [Sage Open] 2016 Jul-Sep; Vol. 6 (3). Date of Electronic Publication: 2016 Jul 15.

Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response.

Autor: Wandu WS; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Tan C; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Ogbeifun O; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Vistica BP; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Shi G; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Hinshaw SJ; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America., Xie C; Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America., Chen X; Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America., Klinman DM; Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, United States of America., Cai H; Transgenic Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, United States of America., Gery I; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America.

Publikováno v: PloS one [PLoS One] 2015 Jun 11; Vol. 10 (6), pp. e0128906. Date of Electronic Publication: 2015 Jun 11 (Print Publication: 2015).

Induced regulatory T-cells (iTregs) generated by activation with anti-CD3/CD28 antibodies differ from those generated by the physiological-like activation with antigen/APC.

Autor: Zhao C; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Shi G; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States., Vistica BP; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States., Hinshaw SJ; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States., Wandu WS; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States., Tan C; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States., Zhang M; Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address: meifen_zhang@hotmail.com., Gery I; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States. Electronic address: geryi@nei.nih.gov.

Publikováno v: Cellular immunology [Cell Immunol] 2014 Aug; Vol. 290 (2), pp. 179-84. Date of Electronic Publication: 2014 Jun 27.