Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Wanding Zhou"'
Autor:
Hongxiang Fu, Harry Pickering, Liudmilla Rubbi, Ted M. Ross, Wanding Zhou, Elaine F. Reed, Matteo Pellegrini
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background The effect of vaccination on the epigenome remains poorly characterized. In previous research, we identified an association between seroprotection against influenza and DNA methylation at sites associated with the RIG-1 signaling
Externí odkaz:
https://doaj.org/article/299d90b0d0a0472f87d41bcd52d6438d
Autor:
Mahdi Moqri, Andrea Cipriano, Daniel J. Simpson, Sajede Rasouli, Tara Murty, Tineke Anna de Jong, Daniel Nachun, Guilherme de Sena Brandine, Kejun Ying, Andrei Tarkhov, Karolina A. Aberg, Edwin van den Oord, Wanding Zhou, Andrew Smith, Crystal Mackall, Vadim N. Gladyshev, Steve Horvath, Michael P. Snyder, Vittorio Sebastiano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract DNA methylation (DNAm) is one of the most reliable biomarkers of aging across mammalian tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm gain is less characterized. Studies have demonstrated that CpGs wh
Externí odkaz:
https://doaj.org/article/903dd1a324284990bb38ba6fe77d4c37
Autor:
Natalia Carreras-Gallo, Varun B. Dwaraka, Dereje D. Jima, David A. Skaar, Tavis L. Mendez, Antonio Planchart, Wanding Zhou, Randy L. Jirtle, Ryan Smith, Cathrine Hoyo
Publikováno v:
Epigenetics Communications, Vol 4, Iss 1, Pp 1-10 (2024)
Abstract Background Differentially methylated imprint control regions (ICRs) regulate the monoallelic expression of imprinted genes. Their epigenetic dysregulation by environmental exposures throughout life results in the formation of common chronic
Externí odkaz:
https://doaj.org/article/500f8c086872444e8fdf57bfa9362c95
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Oxford Nanopore sequencing can detect DNA methylations from ionic current signal of single molecules, offering a unique advantage over conventional methods. Additionally, adaptive sampling, a software-controlled enrichment method for targete
Externí odkaz:
https://doaj.org/article/5b1aae9388c743c29a522b650f037d70
Autor:
Yee Hoon Foong, Blake Caldwell, Joanne L. Thorvaldsen, Christopher Krapp, Clementina A. Mesaros, Wanding Zhou, Rahul M. Kohli, Marisa S. Bartolomei
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
TET1/2/3 dioxygenases iteratively demethylate 5-methylcytosine, beginning with the formation of 5-hydroxymethylcytosine (5hmC). The post-mitotic brain maintains higher levels of 5hmC than most peripheral tissues, and TET1 ablation studies have unders
Externí odkaz:
https://doaj.org/article/15da1f095f5e460fb87e5885ecd73cc9
Autor:
Diljeet Kaur, Sol Moe Lee, David Goldberg, Nathan J. Spix, Toshinori Hinoue, Hong-Tao Li, Varun B. Dwaraka, Ryan Smith, Hui Shen, Gangning Liang, Nicole Renke, Peter W. Laird, Wanding Zhou
Publikováno v:
Epigenetics Communications, Vol 3, Iss 1, Pp 1-15 (2023)
Abstract Infinium Methylation BeadChips are widely used to profile DNA cytosine modifications in large cohort studies for reasons of cost-effectiveness, accurate quantification, and user-friendly data analysis in characterizing these canonical epigen
Externí odkaz:
https://doaj.org/article/91917cef90fd4805b040cfcf02235f3b
Autor:
Waleed Iqbal, Wanding Zhou
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 1, Pp 48-66 (2023)
Dissecting intercellular epigenetic differences is key to understanding tissue heterogeneity. Recent advances in single-cell DNA methylome profiling have presented opportunities to resolve this heterogeneity at the maximum resolution. While these adv
Externí odkaz:
https://doaj.org/article/a81667cdc9bd48dda26d7dd3753736f2
Publikováno v:
iMeta, Vol 2, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/6b274ad115d543bba34c03fe293f8957
Autor:
Hong-Tao Li, Liya Xu, Daniel J. Weisenberger, Meng Li, Wanding Zhou, Chen-Ching Peng, Kevin Stachelek, David Cobrinik, Gangning Liang, Jesse L. Berry
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Retinoblastoma response to treatment is difficult to predict. Here, the authors show that DNA methylation of cfDNA from aqueous humour is altered in retinoblastoma patients and can be used to identify the molecular subtypes and potentially predict tr
Externí odkaz:
https://doaj.org/article/886629a943b547beaf576f5c2a7767c6
Autor:
Adriana Arneson, Amin Haghani, Michael J. Thompson, Matteo Pellegrini, Soo Bin Kwon, Ha Vu, Emily Maciejewski, Mingjia Yao, Caesar Z. Li, Ake T. Lu, Marco Morselli, Liudmilla Rubbi, Bret Barnes, Kasper D. Hansen, Wanding Zhou, Charles E. Breeze, Jason Ernst, Steve Horvath
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Methods to probe DNA methylation in the majority of non-human mammals are lacking. Here the authors developed a Mammalian Methylation Array that includes 36k well-conserved CpGs in mammals which will facilitate cross-species comparisons. They annotat
Externí odkaz:
https://doaj.org/article/8a6ba8ee9691468fa2b7b8d99e1a4571