Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wandi S. Zhu"'
Autor:
Wandi S. Zhu, Adam J. Litterman, Harshaan S. Sekhon, Robin Kageyama, Maya M. Arce, Kimberly E. Taylor, Wenxue Zhao, Lindsey A. Criswell, Noah Zaitlen, David J. Erle, K. Mark Ansel
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-30 (2023)
Abstract GCLiPP is a global RNA interactome capture method that detects RNA-binding protein (RBP) occupancy transcriptome-wide. GCLiPP maps RBP-occupied sites at a higher resolution than phase separation-based techniques. GCLiPP sequence tags corresp
Externí odkaz:
https://doaj.org/article/d9d0f867d61c4eb2b44c5c8f804f28be
Autor:
Jason A. Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, David F. Choy, Alexis J. Combes, Tristan Courau, Gabriela K. Fragiadakis, Arjun Arkal Rao, Arja Ray, Jessica Tsui, Kenneth Hu, Nicholas F. Kuhn, Matthew F. Krummel, David J. Erle, Kirsten Kangelaris, Aartik Sarma, Zoe Lyon, Carolyn S. Calfee, Prescott G. Woodruff, Rajani Ghale, Eran Mick, Ashley Byrne, Beth Shoshana Zha, Charles Langelier, Carolyn M. Hendrickson, Monique G.P. van der Wijst, George C. Hartoularos, Tianna Grant, Raymund Bueno, David S. Lee, John R. Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Chun Jimmie Ye, Thiru Ramalingam, Jacqueline M. McBride, Fang Cai, Anastasia Teterina, Min Bao, Larry Tsai, Ivan O. Rosas, Aviv Regev, Sharookh B. Kapadia, Rebecca N. Bauer, Carrie M. Rosenberger, Yumiko Abe-Jones, Michael Adkisson, K. Mark Ansel, Saurabh Asthana, Alexander Beagle, Sharvari Bhide, Cathy Cai, Saharai Caldera, Maria Calvo, Sidney A. Carrillo, Suzanna Chak, Stephanie Christenson, Zachary Collins, Spyros Darmanis, Angela Detweiler, Catherine DeVoe, Walter Eckalbar, Jeremy Giberson, Ana Gonzalez, Gracie Gordon, Paula Hayakawa Serpa, Alejandra Jauregui, Chayse Jones, Serena Ke, Divya Kushnoor, Tasha Lea, Deanna Lee, Aleksandra Leligdowicz, Yale Liu, Salman Mahboob, Lenka Maliskova, Michael Matthay, Elizabeth McCarthy, Priscila Muñoz-Sandoval, Norma Neff, Viet Nguyen, Nishita Nigam, Randy Parada, Maira Phelps, Logan Pierce, Priya Prasad, Sadeed Rashid, Gabriella Reeder, Nicklaus Rodriguez, Bushra Samad, Andrew Schroeder, Cole Shaw, Alan Shen, Austin Sigman, Pratik Sinha, Matthew Spitzer, Sara Sunshine, Kevin Tang, Luz Torres Altamirano, Alexandra Tsitsiklis, Erden Tumurbaatar, Vaibhav Upadhyay, Alexander Whatley, Andrew Willmore, Michael Wilson, Juliane Winkler, Kristine Wong, Kimberly Yee, Michelle Yu, Mingyue Zhou, Wandi S. Zhu
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107813- (2023)
Summary: Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with acute lung injury from SARS-CoV-2 or other causes across
Externí odkaz:
https://doaj.org/article/9fcf76e7c2d9439cbd17b0a0b7fa8d89
Autor:
Rakesh Chatrikhi, Michael J. Mallory, Matthew R. Gazzara, Laura M. Agosto, Wandi S. Zhu, Adam J. Litterman, K. Mark Ansel, Kristen W. Lynch
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2795-2806.e3 (2019)
Summary: The 3′ UTR (UTR) of human mRNAs plays a critical role in controlling protein expression and function. Importantly, 3′ UTRs of human messages are not invariant for each gene but rather are shaped by alternative polyadenylation (APA) in a
Externí odkaz:
https://doaj.org/article/24e2d5b4eee94f89b827dc74c1f9e0e4
Autor:
Benjamin D Wheeler, John D Gagnon, Wandi S Zhu, Priscila Muñoz-Sandoval, Simon K Wong, Dimitre S Simeonov, Zhongmei Li, Rachel Debarge, Matthew Spitzer, Alexander Marson, K Mark Ansel
Proper activation of cytotoxic T cells via the T cell receptor and the costimulatory receptor CD28 is essential for adaptive immunity against viruses, many intracellular bacteria and cancers. Through biochemical analysis of RNA:protein interactions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::839d94b7265bf9f353faffa4e529b896
https://doi.org/10.1101/2023.04.14.536843
https://doi.org/10.1101/2023.04.14.536843
Autor:
Sagar P. Bapat, Caroline Whitty, Cody T. Mowery, Yuqiong Liang, Arum Yoo, Zewen Jiang, Michael C. Peters, Ling-juan Zhang, Ian Vogel, Carmen Zhou, Vinh Q. Nguyen, Zhongmei Li, Christina Chang, Wandi S. Zhu, Annette T. Hastie, Helen He, Xin Ren, Wenli Qiu, Sarah G. Gayer, Chang Liu, Eun Jung Choi, Marlys Fassett, Jarish N. Cohen, Jamie L. Sturgill, Laura E. Crotty Alexander, Jae Myoung Suh, Christopher Liddle, Annette R. Atkins, Ruth T. Yu, Michael Downes, Sihao Liu, Barbara S. Nikolajczyk, In-Kyu Lee, Emma Guttman-Yassky, K. Mark Ansel, Prescott G. Woodruff, John V. Fahy, Dean Sheppard, Richard L. Gallo, Chun Jimmie Ye, Ronald M. Evans, Ye Zheng, Alexander Marson
Publikováno v:
Nature, vol 604, iss 7905
Decades of work have elucidated cytokine signalling and transcriptional pathways that control T cell differentiation and haveled the way to targeted biologic therapies that are effective in a range of autoimmune, allergic and inflammatory diseases. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2437f4952bbe1f222362a7c14dbf448
https://escholarship.org/uc/item/2bv4q0k3
https://escholarship.org/uc/item/2bv4q0k3
Autor:
Kwok W. Im, Wandi S Zhu, Carolyn S. Calfee, Sidney A. Carrillo, Colin R. Zamecnik, Nayvin W. Chew, Aleksandra Leligdowicz, Jessica Tsui, Gabriella C Reeder, Charles Langelier, Mélia Magnen, Yang Sun, David Lee, Nicholas F. Kuhn, Nina K. Serwas, William S. Chen, Simon J. Cleary, Carolyn M. Hendrickson, David J. Erle, Mark R. Looney, Alexis J. Combes, Alan Shen, Kirsten N. Kangelaris, Kenneth H. Hu, Arja Ray, Arjun A. Rao, Alyssa Ward, Michael A. Matthay, Lauren Rodriguez, Gabriela K. Fragiadakis, Ran You, Chun Jimmie Ye, Priscila Muñoz-Sandoval, Kamir J Hiam-Galvez, Vincent Chan, Divyashree Kushnoor, Michael R. Wilson, Matthew F. Krummel, Prescott G. Woodruff, Rita P. Loudermilk, Tristan Courau
Publikováno v:
Nature
Although infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has pleiotropic and systemic effects in some individuals1-3, many others experience milder symptoms. Here, to gain a more comprehensive understanding of the distinct
Autor:
Carolyn S. Calfee, Wandi S Zhu, Nicholas F. Kuhn, Aleksandra Leligdowicz, Mark R. Looney, Alexis J. Combes, Alyssa Ward, Divyashree Kushnoor, Michael R. Wilson, David Lee, Kenneth H. Hu, Arja Ray, William S. Chen, Carolyn M. Hendrickson, Lauren Rodriguez, David J. Erle, Kirsten N. Kangelaris, Colin R. Zamecnik, Nayvin W. Chew, Jessica Tsui, Gabriella C Reeder, Arjun A. Rao, Kamir J Hiam-Galvez, Yang Sun, Prescott G. Woodruff, Simon J. Cleary, Michael A. Matthay, Chun Jimmie Ye, Ran You, Gabriela K. Fragiadakis, Sidney A. Carrillo, Alan Shen, Priscila Muñoz-Sandoval, Tristan Courau, Charles Langelier, Vincent Chan, Rita P. Loudermilk, Mélia Magnen, Matthew F. Krummel
Publikováno v:
bioRxiv
Research Square
article-version (status) pre
article-version (number) 1
Research Square
article-version (status) pre
article-version (number) 1
While SARS-CoV-2 infection has pleiotropic and systemic effects in some patients, many others experience milder symptoms. We sought a holistic understanding of the severe/mild distinction in COVID-19 pathology, and its origins. We performed a whole-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7154dfd5941d35d9842e8ebca64017d
https://europepmc.org/articles/PMC7605559/
https://europepmc.org/articles/PMC7605559/
Autor:
Alan Shen, Colin R. Zamecnik, Alyssa Ward, Prescott G. Woodruff, Chun Jimmie Ye, Carolyn M. Hendrickson, Lauren Rodriguez, Rita P. Loudermilk, Kenneth H. Hu, Arja Ray, Arjun A. Rao, Priscila Muñoz-Sandoval, Sidney A. Carrillo, Charles Langelier, Mélia Magnen, Vincent Chan, Carolyn S. Calfee, Matthew F. Krummel, Tristan Courau, Ran You, Aleksandra Leligdowicz, Divyashree Kushnoor, Michael R. Wilson, Simon J. Cleary, Michael A. Matthay, Kamir J Hiam-Galvez, Kirsten N. Kangelaris, Gabriela K. Fragiadakis, William S. Chen, David Lee, Nina K. Serwas, Yang Sun, Mark R. Looney, Alexis J. Combes, Nicholas F. Kuhn, David J. Erle, Nayvin W. Chew, Jessica Tsui, Gabriella C Reeder, Kwok W. Im, Wandi S Zhu
Publikováno v:
Nature. 596:E8-E8
Autor:
Noah Zaitlen, Wandi S Zhu, David J. Erle, Robin Kageyama, Wenxue Zhao, Adam J. Litterman, Ansel Km
RNA binding proteins (RBPs) mediate constitutive RNA metabolism and gene specific regulatory interactions. To identify RNA cis-regulatory elements, we developed GCLiPP, a biochemical technique for detecting RBP occupancy transcriptome-wide. GCLiPP se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f831a6b2fe3a4c2a71443cb3eb591bc5
https://doi.org/10.1101/448654
https://doi.org/10.1101/448654
Autor:
Michael J. Mallory, Matthew R. Gazzara, K. Mark Ansel, Rakesh Chatrikhi, Kristen W. Lynch, Wandi S. Zhu, Adam J. Litterman, Laura M. Agosto
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2795-2806.e3 (2019)
Cell reports
Cell reports, vol 28, iss 11
Cell reports
Cell reports, vol 28, iss 11
SUMMARY The 3′ UTR (UTR) of human mRNAs plays a critical role in controlling protein expression and function. Importantly, 3′ UTRs of human messages are not invariant for each gene but rather are shaped by alternative polyadenylation (APA) in a c