Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Wanderson D. DaRocha"'
Autor:
Jose L. Saenz-Garcia, Beatriz S. Borges, Normanda Souza-Melo, Luiz V. Machado, Juliana S. Miranda, Lisandro Alfonso Pacheco-Lugo, Nilmar S. Moretti, Richard Wheleer, Lia C. Soares Medeiros, Wanderson D. DaRocha
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
The flagellum of Trypanosomatids is an organelle that contributes to multiple functions, including motility, cell division, and host–pathogen interaction. Trypanin was first described in Trypanosoma brucei and is part of the dynein regulatory compl
Externí odkaz:
https://doaj.org/article/c08ffe2e03534888b5e0d5b986970f6d
Autor:
Santuza M. Teixeira, Rita Márcia Cardoso de Paiva, Monica M. Kangussu-Marcolino, Wanderson D. DaRocha
Publikováno v:
Genetics and Molecular Biology, Vol 35, Iss 1, Pp 1-17 (2012)
In 2005, draft sequences of the genomes of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major, also known as the Tri-Tryp genomes, were published. These protozoan parasites are the causative agents of three distinct insect-borne diseases, nam
Externí odkaz:
https://doaj.org/article/90933beadc484be3a9a8ef28bff3c449
Autor:
Wanderson D. DaRocha, José L. Sáenz-Garcia, Rodrigo S.C. Brant, Yirys Díaz-Olmos, Lisandro Pacheco-Lugo, Rodrigo Netto-Costa
Publikováno v:
International Journal for Parasitology
Repositorio Digital USB
Universidad Simón Bolívar
instacron:Universidad Simón Bolívar
Repositorio Digital USB
Universidad Simón Bolívar
instacron:Universidad Simón Bolívar
The genetic manipulation of Trypanosoma cruzi continues to be a challenge, mainly due to the lack of available and efficient molecular tools. The CRE-lox recombination system is a site-specific recombinase technology, widely used method of achieving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e371e7fd63ad663c0f9156478b996194
https://doi.org/10.1016/j.ijpara.2020.06.010
https://doi.org/10.1016/j.ijpara.2020.06.010
Autor:
Melissa Soares-Simões, Gabriela de Assis Burle-Caldas, Wanderson D. DaRocha, Santuza M. R. Teixeira, Laiane Lemos-Pechnicki
Publikováno v:
International Journal for Parasitology. 48:591-596
CRISPR/Cas9 technology has been used to edit genomes in a variety of organisms. Using the GP72 gene as a target sequence, we tested two distinct approaches to generate Trypanosoma cruzi knockout mutants using the Cas9 nuclease and in vitro transcribe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d427329eefaa9eadd7f23d5eb63793c
https://doi.org/10.1016/j.ijpara.2018.02.002
https://doi.org/10.1016/j.ijpara.2018.02.002
Autor:
Melissa Soares-Simões, Viviane Grazielle-Silva, Isabel Roditi, Santuza M. R. Teixeira, Wanderson D. DaRocha, Gabriela Schumann Burkard, Gabriela de Assis Burle-Caldas
Publikováno v:
Molecular and Biochemical Parasitology. 212:28-32
Gene function studies in Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, have been hindered by the lack of efficient genetic manipulation protocols. In most organisms, insertion and deletion of DNA fragments in the genome are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04be947aea500062a6370da4475d5e
https://doi.org/10.1016/j.molbiopara.2017.01.002
https://doi.org/10.1016/j.molbiopara.2017.01.002
Autor:
Lisandro Pacheco-Lugo, Juliana Miranda, José L. Sáenz-Garcia, Emily da Silva Córneo, Ricardo Andrez Machado-de-Ávila, Juliana de Moura, Isabel B. Yamanaka, Wanderson D. DaRocha
Publikováno v:
Experimental parasitology. 210
Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi, which is transmitted by insects of the family Reduviidae. Since conventional treatments with nitrohe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257bdf1cbfa68f7ad6bc73065726f936
https://pubmed.ncbi.nlm.nih.gov/31917970
https://pubmed.ncbi.nlm.nih.gov/31917970
Autor:
Ana Paula da Cunha, Wanderson D. DaRocha, James P. Herman, Andréa Rodrigues Ávila, Monica Mendes Kangussu-Marcolino
Publikováno v:
Molecular and Biochemical Parasitology. 198:71-74
The scarcity of molecular tools for genetic manipulation is a critical obstacle for functional genomics studies on Trypanosoma cruzi. The current study adapted an inducible site-specific recombination system based on Dimerizable CRE recombinase (DiCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119a5e1d089a83bfa97e60d377c51378
https://doi.org/10.1016/j.molbiopara.2015.01.001
https://doi.org/10.1016/j.molbiopara.2015.01.001
Autor:
Andres Mojoli, Wanderson D. DaRocha, Marcel I. Ramirez, Iara de Messias-Reason, Ingrid Evans-Osses, Denise Endo da Costa, Marcia Holsbach Beltrame, Thirumalaisamy P. Velavan
Publikováno v:
FEBS Letters. 588:956-961
To produce an infection Trypanosoma cruzi must evade lysis by the complement system. During early stages of infection, the lectin pathway plays an important role in host defense and can be activated by binding of mannan-binding lectin (MBL) to carboh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1474a469c369dc11945243fcce7bf76b
https://doi.org/10.1016/j.febslet.2014.01.054
https://doi.org/10.1016/j.febslet.2014.01.054
Autor:
Christian Probst, Lisandro Pacheco-Lugo, Yirys Díaz-Olmos, Wanderson D. DaRocha, José L. Sáenz-Garcia
Publikováno v:
Parasitology international. 66(3)
New opportunities have raised to study the gene function approaches of Trypanosoma cruzi after its genome sequencing in 2005. Functional genomic approaches in Trypanosoma cruzi are challenging due to the reduced tools available for genetic manipulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbace06a2b18271799112bf844752822
https://pubmed.ncbi.nlm.nih.gov/28137669
https://pubmed.ncbi.nlm.nih.gov/28137669
Autor:
Vinicius A. Weiss, Fábio O. Pedrosa, Leda S. Chubatsu, Michelle Z. Tadra-Sfeir, Helison Faoro, Leonardo M. Cruz, Marcelo Müller-Santos, Thalita Regina Tuleski, Wanderson D. DaRocha, Rose A. Monteiro, Eduardo Balsanelli, Valter Antonio de Baura, Roseli Wassem, Luciano F. Huergo, Emanuel Maltempi de Souza
Publikováno v:
FEMS Microbiology Ecology. 80:441-451
Herbaspirillum rubrisubalbicans M1 causes the mottled stripe disease in sugarcane cv. B-4362. Inoculation of this cultivar with Herbaspirillum seropedicae SmR1 does not produce disease symptoms. A comparison of the genomic sequences of these closely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d10d768532acce565e1931b3f8e935e
https://doi.org/10.1111/j.1574-6941.2012.01309.x
https://doi.org/10.1111/j.1574-6941.2012.01309.x