Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wande M. Oluyemi"'
Autor:
Wande M. Oluyemi, Goodness Nwokebu, Adeniyi T. Adewumi, Shadrach C. Eze, Chinedu C. Mbachu, Emmanuel C. Ogueli, Ngozi Nwodo, Mahmoud E.S. Soliman, Salerwe Mosebi
Publikováno v:
Chemical Physics Impact, Vol 9, Iss , Pp 100703- (2024)
Dihydrofolate reductase (DHFR) enzyme regulates de-novo folate synthesis in Plasmodium falciparum, hence a critical malaria drug target. Pyrimethamine inhibits DHFR, but resistance and lack of cross-species activity are key challenges. Therefore, thi
Externí odkaz:
https://doaj.org/article/7552f186004047a58c026536515a3229
Autor:
Mahmoud E.S. Soliman, Adeniyi T. Adewumi, Wande M. Oluyemi, Nonhlanhla Adewumi, Yemi A. Adekunle, Mohamed Issa Alahmdi, Nader E. Abo-Dyai
Publikováno v:
Current Topics in Medicinal Chemistry. 23
Background: β-ketoacyl-ACP synthase I (KasA I) enzyme is crucial in mycolic acid synthesis via catalytic condensation reactions, hence implicated in M. tuberculosis’s virulence and drug resistance. Presently, there is no known potent KasA inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e10b6c5f8377daae002ce8c5bda244
https://doi.org/10.2174/1568026623666230125124433
https://doi.org/10.2174/1568026623666230125124433
Autor:
Adeniyi T. Adewumi, Wande M. Oluyemi, Yemi A. Adekunle, Nonhlanhla Adewumi, Mohamed Issa Alahmdi, Mahmoud E. S. Soliman, Nader E. Abo‐Dya
Publikováno v:
ChemistrySelect. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d100a99a490f6b9eedbf0e616c0de4f
https://doi.org/10.1002/slct.202203877
https://doi.org/10.1002/slct.202203877
Autor:
Wande M. Oluyemi, Babatunde B. Samuel, Adeniyi T. Adewumi, Yemi A. Adekunle, Mahmoud E. S. Soliman, Liselotte Krenn
Publikováno v:
Chemistrybiodiversity. 19(2)
Multidrug resistance is a significant drawback in malaria treatment, and mutations in the active sites of the many critical antimalarial drug targets have remained challenging. Therefore, this has necessitated the global search for new drugs with new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ece0f9fcffc6b6db78f0c86340af0d
https://pubmed.ncbi.nlm.nih.gov/34982514
https://pubmed.ncbi.nlm.nih.gov/34982514
Autor:
Sarah D'Alessandro, Wande M. Oluyemi, Martin Zehl, Liselotte Krenn, Hanspeter Kaehlig, Donatella Taramelli, B.B. Samuel, Silvia Parapini
Publikováno v:
Journal of ethnopharmacology. 247
Ethnopharmacological relevance Combretum racemosum showed activity in previous ethnopharmacological investigations of some Combretum species used in malaria treatment in parts of West Africa. Aim of the study: This study aimed at confirming the antim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9af181393062f7c01ec84be22161305
https://pubmed.ncbi.nlm.nih.gov/31472271
https://pubmed.ncbi.nlm.nih.gov/31472271
Publikováno v:
ACTA Pharmaceutica Sciencia. 57:21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b5ac2418c4f9ca64f1fee362e4cd89c
https://doi.org/10.23893/1307-2080.aps.05715
https://doi.org/10.23893/1307-2080.aps.05715