Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wandaliz Torres-Garcia"'
Autor:
Valerie Y. Odeh‐Couvertier, Nathan J. Dwarshuis, Maxwell B. Colonna, Bruce L. Levine, Arthur S. Edison, Theresa Kotanchek, Krishnendu Roy, Wandaliz Torres‐Garcia
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract Large‐scale, reproducible manufacturing of therapeutic cells with consistently high quality is vital for translation to clinically effective and widely accessible cell therapies. However, the biological and logistical complexity of manufac
Externí odkaz:
https://doaj.org/article/5bc5f7736edf445dad237c85b52c5a43
Autor:
null Valerie Y. Odeh‐Couvertier, null Nathan J. Dwarshuis, null Maxwell B. Colonna, null Bruce L. Levine, null Arthur S. Edison, null Theresa Kotanchek, null Krishnendu Roy, null Wandaliz Torres‐Garcia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::101b1f902839e9aa362c55d427157017
https://doi.org/10.1002/btm2.10282/v2/response1
https://doi.org/10.1002/btm2.10282/v2/response1
Publikováno v:
EPiC Series in Computing.
Gene interactions play a fundamental role in the proneness to cancer. However, detect- ing and ranking these interactions is a complex problem due to the high dimensionality of genomic data. Hence, we aim to find patterns composed of multiple feature
Autor:
Jose A. Karam, Kanishka Sircar, Roel G.W. Verhaak, Horatiu Voicu, Eric Jonasch, Keith A. Baggerly, Khalida Wani, Kenneth Aldape, Tadeusz Majewski, Nizar M. Tannir, Suk Young Yoo, Lalit R. Patel, Bogdan Czerniak, Wandaliz Torres-Garcia, Christopher G. Wood, Pheroze Tamboli
Publikováno v:
The Journal of Pathology: Clinical Research. 1:212-224
Sarcomatoid transformation, wherein an epithelioid carcinomatous tumour component coexists with a sarcomatoid histology, is a predictor of poor prognosis in clear cell renal cell carcinoma. Our understanding of sarcomatoid change has been hindered by
Autor:
Yong Mao, Cameron Brennan, Dimpy Koul, Wandaliz Torres-Garcia, Aaron McKenna, Jun Fu, Shuzhen Wang, W. K. Alfred Yung, Lindsey Heathcock, Roeland Verhaak, Ken Chen, Erik P. Sulman, Siyuan Zheng, Ravesanker Ezhilarasan, John N. Weinstein, Rahulsimham Vegesna, Kenneth D. Aldape, Lynda Chin
Publikováno v:
Cell Cycle
With the advent of high-throughput sequencing technologies, much progress has been made in the identification of somatic structural rearrangements in cancer genomes. However, characterization of the complex alterations and their associated mechanisms
Autor:
Kelinda Tucker, Raju Kucherlapati, Ng Sam, John N. Weinstein, Lori Boice, Satish K. Tickoo, Saianand Balu, John C. Cheville, B. Arman Aksoy, Chip Stewart, Preethi H. Gunaratne, Martin L. Ferguson, Bogdan Czerniak, Christie Kovar, Theodore C. Goldstein, Mark E. Sherman, Juan M. Mosquera, Chris Sander, Yaron S.N. Butterfield, Leigh Anne Zach, Yiling Lu, Chandra Lebovitz, Gary Witkin, David Pot, Gordon Robertson, Richard A. Gibbs, James J. Hsieh, Benjamin P. Berman, Doug Voet, Kyle Chang, W. Marston Linehan, Margaret Morgan, Joan Pontius, Jodi Harr, Lihua Zhou, Joel S. Parker, David Van Den Berg, Michael B. Atkins, Sheila Reynolds, Petar Stojanov, Joel B. Nelson, Gordon B. Mills, Toni K. Choueiri, Weimin Xiao, Hye Jung E. Chun, Ronglai Shen, Rebecca Carlsen, Jennifer Brown, Tod D. Casasent, Sabina Signoretti, Jo Ellen Weaver, Phillip H. Lai, Dominique L. Berton, Patrick Plettner, Irina Ostrovnaya, Lisle E. Mose, Leslie Cope, Nils Gehlenborg, Heidi J. Sofia, Peter J. Park, Scott Morris, Hsin-Ta Wu, Fabio Vandin, Ranabir Guin, Daniel E. Carlin, Jacqueline E. Schein, Xi Liu, Nils Weinhold, Wandaliz Torres-Garcia, Cureline Olga Potapova, Daniel DiCara, Juok Cho, Steve Schumacher, Chris Wakefield, A. Rose Brannon, Susan M. Benton, Tom Bodenheimer, J. Todd Auman, Brenda Rabeno, Sharon M. Gorski, Eric E. Snyder, Divya Kalra, Brenda Ayala, Jiashan Zhang, Zhang Wei, Kyle Ellrott, Zhining Wang, Stacey Gabriel, Dominik Stoll, Daniel L. Rubin, W. Kimryn Rathmell, Eric Chuah, David Mallery, Tanja Davidsen, David Cogdell, Anders Jacobsen, John A. Demchok, Robert C. Onofrio, Anna Chu, Piotr A. Mieczkowski, Zhiyong Ding, Erin Curley, Johanna Gardner, Robert Worrell, Hailei Zhang, Jennifer C. Fisher, Donna M. Muzny, Rajiv Dhir, Walker Hale, Ari B. Kahn, Sheila Fisher, Giovanni Ciriello, Ken Burnett, Marco A. Marra, Wiam Bshara, Anil V. Parwani, Joshua M. Stuart, Richard Varhol, Kristin G. Ardlie, Han Yi, Lisa R. Trevino, Roy Tarnuzzer, Michael S. Noble, Erin Pleasance, Jesse Walsh, Leigh B. Thorne, Andy Chu, Peter W. Laird, Andrew J. Mungall, Rashmi N. Sanbhadti, Mark Backus, David A. Wheeler, Bradley A. Ozenberger, Jodi K. Maranchie, William Mallard, Jared R. Slobodan, Christine Czerwinski, Jireh Santibanez, Andrew J. Stout, Donghui Tan, Laura S. Schmidt, Junyuan Wu, Jianjiong Gao, Daniel J. Weisenberger, D. Neil Hayes, Scott Frazer, Alan P. Hoyle, Konstantin V. Fedosenko, Rehan Akbani, Todd Pihl, Rahul Vegesna, Lynda Chin, Shelley Alonso, Jeffrey G. Reid, Donna Morton, Cathy D. Vocke, R. Houston Thompson, Christopher C. Benz, Kenna R. Mills Shaw, Liming Yang, Carmelo Gaudioso, Nianxiang Zhang, Caleb F. Davis, Carrie Hirst, Shi Yan, Michael L. Blute, Barry S. Taylor, Mathew G. Soloway, Nina Thiessen, Paul T. Spellman, Deepak Srinivasan, Yongjun Zhao, Boris Reva, Wang Min, Stuart R. Jefferys, Benjamin J. Raphael, Nicholas J. Petrelli, Arash Shafiei, Lora Lewis, Eric Jonasch, David I. Heiman, Scot Waring, Richard A. Moore, Eric S. Lander, Evan O. Paull, Hoon Kim, Janae V. Simons, Stephen B. Baylin, Gad Getz, Stanley Girshik, Victor E. Reuter, Benjamin Gross, Ethan Cerami, Andrew D. Cherniack, Christine I. Smith, Christina Yau, Michael D. Topal, Peter Waltman, Jeff Boyd, Rameen Beroukhim, Angela Tam, Yingchun Liu, Peter A. Kigonya, Miruna Balasundaram, Maria J. Merino, David Haussler, Dinh Huyen, Elizabeth Buda, Michael S. Lawrence, Lin Pei, Charles M. Perou, Timothy J. Triche, Jessica Walton, Greg Eley, Tiffany Ting Liu, Joseph Paulauskis, Matthew Meyerson, Marc Ladanyi, Jaegil Kim, Katherine A. Hoadley, Huang Mei, Ilya Shmulevich, Robin J.N. Coope, Mary Iacocca, Natasja Wye, Adrian Ally, Mark A. Rubin, A. Ari Hakimi, Lori Huelsenbeck-Dill, Steven J.M. Jones, James Peterson, Mark A. Jensen, Barbara Tabak, Andrey Sivachenko, Julie Bergsten, John Eckman, Inanc Birol, Rohini Raman, Nipun Kakkar, Christina Liquori, Rileen Sinha, Dennis T. Maglinte, Lichtenstein Lee, Haiyan I. Li, William G. Kaelin, Anna K. Unruh, Noreen Dhalla, Candace Shelton, Roel G.W. Verhaak, Christopher J. Ricketts, Carrie Sougnez, Harsha Doddapaneni, Mark S. Guyer, Robert Penny, Michael F. Berger, Margi Sheth, Darlene Lee, Dimitra Tsavachidou, Chad J. Creighton, Prachi Kothiyal, Scott L. Carter, Michael Mayo, Zhu Jing, Kenneth Aldape, Corbin D. Jones, Moiz S. Bootwalla, Payal Sipahimalani, Martin Hirst, Sean P. Barletta, Kristian Cibulskis, Jerome Myers, Matthew C. Nicholls, Yidi J. Turman, Julien Baboud, Jeff Gentry, Carl Morrison, Gordon Saksena, Troy Shelton, Swapna Mahurkar, Robert A. Holt, Robert Sfeir, Shen Hui, Suzanne S. Fei, Christopher G. Wood, Candace Carter, S. Onur Sumer, Pheroze Tamboli, Yiming Zhu
Publikováno v:
Nature
Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, PBRM1). We surveyed more than 400 tumours usi
Autor:
Rahulsimham Vegesna, Qianghu Wang, Wandaliz Torres-Garcia, Roel G.W. Verhaak, Siyuan Zheng, Hoon Kim, Kosuke Yoshihara
Publikováno v:
Oncogene
Transcript fusions as a result of chromosomal rearrangements have been a focus of attention in cancer as they provide attractive therapeutic targets. To identify novel fusion transcripts with the potential to be exploited therapeutically, we analyzed
Autor:
Wandaliz Torres-Garcia, Michael F. Berger, Rong Yao, Gad Getz, Qianghu Wang, Siyuan Zheng, Roel G.W. Verhaak, John N. Weinstein, Rahulsimham Vegesna, Andrey Sivachenko
Summary: Technological advances in high-throughput sequencing necessitate improved computational tools for processing and analyzing large-scale datasets in a systematic automated manner. For that purpose, we have developed PRADA (Pipeline for RNA-Seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1c7549a581ee3af4f927de03a272b9
https://europepmc.org/articles/PMC4103589/
https://europepmc.org/articles/PMC4103589/
Publikováno v:
Bioinformatics (Oxford, England). 25(15)
Motivation: Gene expression profiling technologies can generally produce mRNA abundance data for all genes in a genome. A dearth of proteomic data persists because identification range and sensitivity of proteomic measurements lag behind those of tra
Autor:
Kosuke Yoshihara, Siyuan Zheng, Rahulsimham Vegesna, Wandaliz Torres-Garcia, Qianghu Wang, Hoon Kim, Roel G.W. Verhaak
Publikováno v:
Cancer Research. 75:3762-3762
Gene fusions are an important class of cancer-contributing somatic alteration, and have an important significance as a tumor-initiating event and as a molecular therapeutic target for specific tumors. We analyzed RNA sequencing, DNA copy number and g