Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wanda Stirling"'
Autor:
Bobby Thomas, Allen S. Mandir, Neva West, Ying Liu, Shaida A. Andrabi, Wanda Stirling, Valina L. Dawson, Ted M. Dawson, Michael K. Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/e68a3298f3114f5aa480f902061ff7b9
Autor:
Bobby Thomas, Allen S Mandir, Neva West, Ying Liu, Shaida A Andrabi, Wanda Stirling, Valina L Dawson, Ted M Dawson, Michael K Lee
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16706 (2011)
Genetic and biochemical abnormalities of α-synuclein are associated with the pathogenesis of Parkinson's disease. In the present study we investigated the in vivo interaction of mouse and human α-synuclein with the potent parkinsonian neurotoxin, M
Externí odkaz:
https://doaj.org/article/7e4bdda06f3a4f10a3b7d914de48c44b
Autor:
Alena Savonenko, Mi Jeong Yoo, Mary E. Blue, David R. Borchelt, Donald L. Price, Laura A. Mamounas, Michael K. Lee, Ying Liu, W. Ernest Lyons, Wanda Stirling
Publikováno v:
The Journal of Neuroscience. 28:13805-13814
β-Amyloid (Aβ) pathology is an essential pathogenic component in Alzheimer's disease (AD). However, the significance of Aβ pathology, including Aβ deposits/oligomers and glial reactions, to neurodegeneration is unclear. In particular, despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d5342085d546a3956f76cdc65ccb98
https://doi.org/10.1523/jneurosci.4218-08.2008
https://doi.org/10.1523/jneurosci.4218-08.2008
Autor:
Kristy Bruno, Ted M. Dawson, Ellen J. Hess, Shaida A. Andrabi, Valina L. Dawson, Rainer von Coelln, Joseph M. Savitt, Roya Saffary, Kah-Leong Lim, Bobby Thomas, Michael K. Lee, Wanda Stirling
Publikováno v:
The Journal of Neuroscience. 26:3685-3696
Mutations in the genes coding for alpha-synuclein and parkin cause autosomal-dominant and autosomal-recessive forms of Parkinson's disease (PD), respectively. Alpha-synuclein is a major component of Lewy bodies, the proteinaceous cytoplasmic inclusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a27abe500485086730fbe62b2d06f4
https://doi.org/10.1523/jneurosci.0414-06.2006
https://doi.org/10.1523/jneurosci.0414-06.2006
Publikováno v:
Journal of Neurochemistry. 88:401-410
Biochemical and genetic abnormalities of alpha-synuclein (alpha-Syn) are implicated in the pathogenesis of Parkinson's disease (PD) and other alpha-synucleinopathies. The abnormal intraneuronal accumulations of alpha-Syn in Lewy bodies (LBs) and Lewy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c11d6259b0bf1a4e9d88d3c376b683f
https://doi.org/10.1046/j.1471-4159.2003.02166.x
https://doi.org/10.1046/j.1471-4159.2003.02166.x
Autor:
Bobby Thomas, Allen S. Mandir, Neva West, Ying Liu, Shaida A. Andrabi, Wanda Stirling, Valina L. Dawson, Ted M. Dawson, Michael K. Lee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3 (2012)
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1d94dea881bc59565aeccb1772f342
http://europepmc.org/articles/PMC3307770
http://europepmc.org/articles/PMC3307770
Autor:
Valina L. Dawson, Allen S. Mandir, Bobby Thomas, Shaida A. Andrabi, Neva West, Michael K. Lee, Ted M. Dawson, Wanda Stirling, Ying Liu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e16706 (2011)
PLoS ONE, Vol 6, Iss 1, p e16706 (2011)
Genetic and biochemical abnormalities of α-synuclein are associated with the pathogenesis of Parkinson's disease. In the present study we investigated the in vivo interaction of mouse and human α-synuclein with the potent parkinsonian neurotoxin, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e14419369ff1ef9dd29ad4c3d0f22b3
http://europepmc.org/articles/PMC3031616
http://europepmc.org/articles/PMC3031616
Autor:
Richard B.S. Roden, Wanda Stirling, Martina Bazzaro, Ie Ming Shih, Alessia Zoso, Antonio Santillan, Michael K. Lee
Publikováno v:
Cancer research. 66(7)
The ubiquitin-proteasome system (UPS) mediates targeted protein degradation. Notably, the UPS determines levels of key checkpoint proteins controlling apoptosis and proliferation by controlling protein half-life. Herein, we show that ovarian carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a58a2dfe7bbab0f04bb561a27cbb77
https://pubmed.ncbi.nlm.nih.gov/16585202
https://pubmed.ncbi.nlm.nih.gov/16585202
Publikováno v:
Journal of neurochemistry. 88(2)
Biochemical and genetic abnormalities of alpha-synuclein (alpha-Syn) are implicated in the pathogenesis of Parkinson's disease (PD) and other alpha-synucleinopathies. The abnormal intraneuronal accumulations of alpha-Syn in Lewy bodies (LBs) and Lewy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d9030970ef6ca2a9dcf3736b9ebadca
https://pubmed.ncbi.nlm.nih.gov/14690528
https://pubmed.ncbi.nlm.nih.gov/14690528
Autor:
Dike Qui, Neal G. Copeland, Allen S. Mandir, Xueying Xu, Nancy A. Jenkins, Wanda Stirling, Donald L. Price, Ted M. Dawson, Yanqun Xu, Michael K. Lee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(13)
Mutations in α-synuclein (α-Syn) cause Parkinson's disease (PD) in a small number of pedigrees with familial PD. Moreover, α-Syn accumulates as a major component of Lewy bodies and Lewy neurites, intraneuronal inclusions that are neuropathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cdafae69f48db972c982a06ceb452e
https://pubmed.ncbi.nlm.nih.gov/12084935
https://pubmed.ncbi.nlm.nih.gov/12084935