Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wanda Górnik"'
CYP2C19 polymorphism affects single-dose pharmacokinetics of oral pantoprazole in healthy volunteers
Autor:
Barbara Gawrońska-Szklarz, Wanda Górnik, Maria Kaldonska, Marek Drozdzik, Urszula Adamiak-Giera, Mateusz Kurzawski, Elżbieta Wyska
Publikováno v:
European Journal of Clinical Pharmacology
Objectives Pantoprazole is metabolized by cytochrome P450 2 C19, which shows genetic polymorphism. The effect of CYP2C19 polymorphism on single-dose pharmacokinetics of oral pantoprazole in healthy volunteers was evaluated. Methods Pantoprazole pharm
Autor:
Rafał Kurzawa, Wanda Górnik, Marek Droździk, Joanna Stefankiewicz, Tomasz Bączkowski, Mateusz Kurzawski
Publikováno v:
Pharmacological Reports. 61:690-696
Infertility is a common problem affecting one in six couples, and in 30% of infertile couples, the male factor is a major cause due to defective sperm quality. P-glycoprotein (P-gp), a product of the MDR1 (ABCB1) gene, may be a link between genetic a
Autor:
Barbara Gawrońska-Szklarz, Wanda Górnik, Andrzej Pawlik, Grażyna Czaja-Bulsa, Joanna Wrześniewska, Teresa Luszawska-Kutrzeba
Publikováno v:
Clinical Pharmacology & Therapeutics. 69:372-378
We investigated whether patients with immunoglobulin E–mediated food allergy differed from healthy individuals with regard to genotype of the polymorphic enzyme N-acetyltransferase 2 (NAT2). The genetic polymorphism of acetylation can alter the tox
Autor:
Barbara Gawrońska-Szklarz, M. Wójcicki, M. Kedzierski, A. Kuprianowicz, Wanda Górnik, Andrzej Pawlik, Karolina Kędzierska
Publikováno v:
European Journal of Clinical Pharmacology. 55:389-392
The aim of the present study was to investigate the distribution of the CYP2D6 and GSTM1 genotypes in a Polish population.One hundred and forty-five unrelated healthy individuals from the western region of Poland were studied. The CYP2D6 genotype was
Publikováno v:
Pulmonary Pharmacology. 9:175-178
The study was carried out on male rabbits divided into two groups: a control and an experimental one, fed on a high-fat diet. Humans were also ascribed into two groups: control and those affected with primary, mixed form of hyperlipidemia. The animal
Autor:
Marek Drozdzik, Wanda Górnik, Joanna Stefankiewicz, Tomasz Baczkowski, Mateusz Kurzawski, Rafał Kurzawa
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 15(3)
Previous studies have revealed that genetic factors may be involved in regulating folate turnover, e.g. methylenetetrahydrofolate reductase polymorphism in the development of male infertility. Folate transporter, encoded by the SLC19A1 gene, commonly
Autor:
Karolina Kędzierska, Mateusz Kurzawski, Krzysztof Dziewanowski, Wanda Górnik, Marek Drozdzik, Anna Banas
Publikováno v:
The pharmacogenomics journal. 10(2)
New-onset, posttransplant diabetes mellitus (PTDM) has a high incidence after kidney transplantation in patients medicated with tacrolimus, and may adversely affect the patient and graft survival. The pathophysiology of PTDM closely mimics that of ty
Autor:
Zygmunt Juzyszyn, Krzysztof Safranow, Marek Drozdzik, Wanda Górnik, Violetta Dziedziejko, Mateusz Kurzawski, Andrzej Pawlik, Barbara Gawrońska-Szklarz
Publikováno v:
Brazilian Journal of Medical and Biological Research, Volume: 42, Issue: 7, Pages: 660-664, Published: JUL 2009
Brazilian Journal of Medical and Biological Research v.42 n.7 2009
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 42, Iss 7, Pp 660-664 (2009)
Brazilian Journal of Medical and Biological Research v.42 n.7 2009
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Vol 42, Iss 7, Pp 660-664 (2009)
Despite the availability of several new agents for the treatment of rheumatoid arthritis (RA), sulfasalazine remains the mainstay because of both cost and experience with its use. Methylenetetrahydrofolate reductase (MTHFR) is involved in folate meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea60df4cb0d5314fec228885039df3c
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000700011&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000700011&lng=en&tlng=en
Publikováno v:
Pharmacological reports : PR. 59(6)
Despite the availability of several new agents for the treatment of rheumatoid arthritis (RA), arechin (hydroxychloroquine) remains the mainstay because of both cost-effectiveness and experience with its use. However, there is considerable variation
Autor:
Lilianna, Bartnicka, Mateusz, Kurzawski, Agnieszka, Drozdzik, Edyta, Plonska-Gosciniak, Wanda, Górnik, Marek, Drozdzik
Publikováno v:
Pharmacological reports : PR. 59(3)
The aim of the present study was to evaluate the effects of ABCB1 ( MDR1 ) gene polymorphism on P-glycoprotein model substrate, i.e. digoxin, salivary secretion. The study was carried out in 77 patients diagnosed with congestive heart failure adminis