Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Wanda Douwenga"'
Autor:
Valentina Pegoretti, Jan Bauer, Roman Fischer, Iskra Paro, Wanda Douwenga, Roland E. Kontermann, Klaus Pfizenmaier, Evelien Houben, Bieke Broux, Niels Hellings, Wia Baron, Jon D. Laman, Ulrich L. M. Eisel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract TNF signaling is an essential regulator of cellular homeostasis. Through its two receptors TNFR1 and TNFR2, soluble versus membrane-bound TNF enable cell death or survival in a variety of cell types. TNF-TNFRs signaling orchestrates importan
Externí odkaz:
https://doaj.org/article/5841bf7052c54683ab34c56469546a89
Autor:
Wanda Douwenga, Eric Guenzi, Doortje W. Dekens, Andreas Herrmann, Eddy A. van der Zee, Roland E. Kontermann, Roman Fischer, Petrus J.W. Naudé, Yun Dong, Klaus Pfizenmaier, Ulrich L. M. Eisel, Maëlle Duffey, Olaf Maier, Csaba Nyakas
Publikováno v:
Proceedings of the National Academy of Science of the United States of America, 113(43), 12304-12309. NATL ACAD SCIENCES
Despite the recognized role of tumor necrosis factor (TNF) in inflammation and neuronal degeneration, anti-TNF therapeutics failed to treat neurodegenerative diseases. Animal disease models had revealed the antithetic effects of the two TNF receptors