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Akademický článek

Rapid screening and isolation of potential xanthine oxidase inhibitors in Ganoderma lucidum

Autor: Wanchao Hou, Xu Zhou, Siyuan Zhuang, Yuchi Zhang, Sainan Li, Chunming Liu

Publikováno v: Arabian Journal of Chemistry, Vol 17, Iss 9, Pp 105925- (2024)

Given the abundance and intricate nature of the chemical components found in natural food ingredients, functional food research has long grappled with two significant technical challenges: rapid and precise screening of active substances and targeted

Externí odkaz: https://doaj.org/article/acff1e96b5f444cd851d05718ba70fb9

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Akademický článek

NSGA-II Genetic Algorithm Combined with Response Surface Methodology to Optimize the Extraction Process of Active Ingredients of Inonotus obliquus

Autor: Haocheng YUN, Fanhua YU, Du CHENG, Zhen LIU, Huazhou NIU, Wanchao HOU, Sainan LI, Chunming LIU, Yuchi ZHANG

Publikováno v: Shipin gongye ke-ji, Vol 43, Iss 17, Pp 185-193 (2022)

This paper aimed to investigate the extraction process of total flavonoids and triterpenes in Inonotus obliquus by ultrasound-assisted enzymatic extraction. The UV spectrophotometric method was used as the detection method, the extraction rate of tot

Externí odkaz: https://doaj.org/article/b378a853f7714a32969203385c4ff501

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Akademický článek

Efficient Combination of Complex Chromatography, Molecular Docking and Enzyme Kinetics for Exploration of Acetylcholinesterase Inhibitors from Poria cocos

Autor: Tong Wu, Wanchao Hou, Chunming Liu, Sainan Li, Yuchi Zhang

Publikováno v: Molecules, Vol 28, Iss 3, p 1228 (2023)

Poria cocos (P. cocos) is a traditional Chinese medicinal product with the same origin as medicine and food. It has diuretic, anti-inflammatory and liver protection properties, and has been widely used in a Chinese medicine in the treatment of Alzhei

Externí odkaz: https://doaj.org/article/8724cd74ec874bf4b2836531087df7c2

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Efficient and fast screening and separation based on computer aided screening and complex chromatography method for 5-lipoxygenase inhibitors from Poria cocos

Autor: Tong Wu, Wanchao Hou, Sainan Li, Chunming Liu, Yuchi Zhang

Poria cocos (Schw.) Wolf (P. cocos) is a traditional Chinese medicinal materia that medicine food homologyl. In this study, based on the β-Amyloid deposition hypothesis of AD, a fast and efficient methods that ultrafiltration-liquid chromatography-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::334c6e0dbedf61acd4f781c9e7003061
https://doi.org/10.21203/rs.3.rs-2914730/v1

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An efficient strategy based on two‐stage chromatography and in vitro evaluation for rapid screening and isolation of acetylcholinesterase inhibitors from Scutellaria baicalensis Georgi

Autor: Wanchao Hou, Chunming Liu, Sainan Li, Yuchi Zhang, Yongri Jin, Xuwen Li, Zhen Liu, Huazhou Niu, Jianli Xia

Publikováno v: Journal of Separation Science. 45:1170-1184

The extraction of Scutellaria baicalensis Georgi was investigated using the response surface methodology-genetic algorithm mathematical regression model, and the extraction variables were optimized to maximize the flavonoid yield. Furthermore, a simp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d50d0f2c91798c0ce919ba656d84b06
https://doi.org/10.1002/jssc.202100918

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Development of a method to screen and isolate xanthine oxidase inhibitors from black bean in a single step: Hyphenation of semipreparative liquid chromatography and stepwise flow rate countercurrent chromatography

Autor: Wanchao Hou, Zhen Liu, Yuchi Zhang, Sainan Li, Chunming Liu, Huazhou Niu, Hao-cheng Yun

Publikováno v: Journal of Separation Science. 45:492-506

Black bean, in which isoflavones are the main active constituent, also contains saponins, and monoterpenes. Soybean isoflavone is a secondary metabolite that is formed during the growth of soybean; it exhibits antioxidant and cardiovascular activitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b64af981c3e5d95b3da51d7861ee0
https://doi.org/10.1002/jssc.202100663

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Development of a method to screen and isolate bioactive constituents from Stellera chamaejasme by ultrafiltration and liquid chromatography combined with semi‐preparative high‐performance liquid chromatography and high‐speed counter current chromatography

Autor: Yu Huang, Sainan Li, Chunming Liu, Wanchao Hou, Jianli Xia, Tong Wu

Publikováno v: Journal of Separation Science. 42:3421-3431

A simple and efficient method based on ultrafiltration with liquid chromatography and mass spectrometry was used for the rapid screening and identification of ligands in the extracts of Stellera chamaejasme. The bound ligands, i.e. daphnoretin, isopi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::915b26dde640b7ca69d57fd8db51682d
https://doi.org/10.1002/jssc.201900772

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Development of ultrasound-assisted centrifugal extraction combined with two countercurrent chromatography systems for the simultaneous extraction and isolation of phytochemicals

Autor: Ruoyao Liu, Chunming Liu, Sainan Li, Yuchi Zhang, Wanchao Hou

Publikováno v: Journal of separation scienceREFERENCES. 44(11)

We proposed a method for the extraction of medicinal herbs, called ultrasound-assisted centrifugal extraction, and an online solvent concentration method. These techniques were coupled with two countercurrent chromatography systems and applied to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4db19192a603209bec3a9054b5e100
https://pubmed.ncbi.nlm.nih.gov/33793077

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