Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Wanchang Cui"'
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/3e4e74c89f584254a924ee25215982c6
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
To date, few FDA-approved medical countermeasures are available for addressing hematopoietic acute radiation syndrome (H-ARS). In this study, we present our latest research findings focusing on the evaluation of a novel radiation mitigator known as t
Externí odkaz:
https://doaj.org/article/e99022922d0d454cabb77f2ba0923e28
Publikováno v:
Animal Microbiome, Vol 5, Iss 1, Pp 1-13 (2023)
Abstract Background Recent studies have shown that gut microbiome plays important roles in response to radiation exposure. IL-18, an inflammatory cytokine, is highly elevated in mice, mini-pigs and nonhuman primates after radiation exposure. Blocking
Externí odkaz:
https://doaj.org/article/16232d5c931a48c0a7c626f5dcbb4a8b
Publikováno v:
Toxics, Vol 12, Iss 1, p 5 (2023)
IL-18 has been shown to play important roles in response to total body irradiation. However, homogenous total body irradiation is not a realistic model to reflect the radiation exposure in a real nuclear event. To further study the roles of IL-18 in
Externí odkaz:
https://doaj.org/article/6f5c0c31749c44c1a581b98a874e1da0
Autor:
Wanchang Cui, Mang Xiao
Publikováno v:
Toxics, Vol 11, Iss 4, p 306 (2023)
Radiation exposure is a complex issue that has both benefits and risks for human health [...]
Externí odkaz:
https://doaj.org/article/53d22735e528415bae9b0a282979e7fc
Autor:
Juliann G. Kiang, Joan T. Smith, Georgetta Cannon, Marsha N. Anderson, Connie Ho, Min Zhai, Wanchang Cui, Mang Xiao
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Background Compared to radiation injury alone (RI), radiation injury combined wound (CI) further enhances acute radiation syndrome and subsequently mortality. We previously reported that therapy with Ghrelin, the 28-amino-acid-peptide secret
Externí odkaz:
https://doaj.org/article/7758123c4aa049a197611c9c832859a8
Autor:
Li Wang, Bin Lin, Min Zhai, Wanchang Cui, Lisa Hull, Alex Zizzo, Xianghong Li, Juliann G. Kiang, Mang Xiao
Publikováno v:
Toxics, Vol 10, Iss 12, p 785 (2022)
Radiation-combined injury (RCI) augments the risk of morbidity and mortality when compared to radiation injury (RI) alone. No FDA-approved medical countermeasures (MCMs) are available for treating RCI. Previous studies implied that RI and RCI elicit
Externí odkaz:
https://doaj.org/article/f2176aeda7ac4e22beee88d7e0c63024
Publikováno v:
Toxics, Vol 11, Iss 1, p 35 (2022)
Administration of recombinant human IL-18 binding protein (rhIL-18BP), a natural antagonist of IL-18, significantly increased mouse survival after lethal doses of irradiation. To further understand the roles of IL-18BP in radiation mitigation, we stu
Externí odkaz:
https://doaj.org/article/2a93094498094adfabcb8901b90e620b
Autor:
Kiang, Mang Xiao, Xianghong Li, Li Wang, Bin Lin, Min Zhai, Lisa Hull, Alex Zizzo, Wanchang Cui, Juliann G.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10701
Radiation injury- and radiation combined with skin injury-induced inflammatory responses in the mouse brain were evaluated in this study. Female B6D2F1/J mice were subjected to a sham, a skin wound (SW), 9.5 Gy 60Co total-body gamma irradiation (RI),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::715f932a16c0b9ce188caa1cab4d0589
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207071 (2018)
DNA damage has been considered to be the universal critical lesion in cells after exposure to ionizing radiation. Measuring radiation-induced DNA damage is important to understand the mechanisms of radiation-induced toxicity and monitor DNA damage re
Externí odkaz:
https://doaj.org/article/1495444be83a4b78a5831c51e66ce913