Zobrazeno 1 - 10
of 198
pro vyhledávání: '"WanZhu Jin"'
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract Obesity causes metabolic disorders and is one of the important risk factors for diabetes. Myokines are widely involved in lipid metabolism through autocrine, paracrine and endocrine actions. FGF21 and Irisin, as representative myokines, can
Externí odkaz:
https://doaj.org/article/f884677a87fa4bc2b40d8e1a8257dbca
Autor:
Xiaoxiao Jiang, Chunlong Yan, Hanlin Zhang, Li Chen, Rui Jiang, Kexin Zheng, Wanzhu Jin, Huijuan Ma, Xiaomeng Liu, Meng Dong
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Alcohol is an essential drug in human life with multiple medical functions, but excessive alcohol intake, even a single episode of binge drinking, can cause serious damage. Reducing alcohol consumption or absorption is a direct way to allevi
Externí odkaz:
https://doaj.org/article/4d0ed03129a9446ca8eb87a7775c5913
Autor:
Miyu Kojima, Hong Liu, Satoshi Takemoto, Yoshihito Suda, Ryo Inoue, Gen Watanabe, Wanzhu Jin, Kentaro Nagaoka
Publikováno v:
Frontiers in Animal Science, Vol 3 (2022)
The initial colonization and early development of the intestinal microbiome are important stages in the growth of calves during pre-weaning. This study investigated temporal changes in the diversity and composition of the fecal microbiota, focusing o
Externí odkaz:
https://doaj.org/article/bee3910442b049409582b52931d43d7f
Autor:
Xiaoxiao Jiang, Jun Lin, Meng Dong, Xiaomeng Liu, Yuanyuan Huang, Hanlin Zhang, Rongcai Ye, Huiqiao Zhou, Chunlong Yan, Shouli Yuan, Li Chen, Rui Jiang, Kexin Zheng, Wanzhu Jin
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The intermittent fasting regimen (IFR) has been certified as an effective strategy for improving metabolism. But the underlying mechanism is still obscure. Beige induction in white adipose tissue (WAT) by IFR may account for this. It has been demonst
Externí odkaz:
https://doaj.org/article/41341786da0b4d57abfcdab8c33cf7b4
Autor:
Xiaojuan Liang, Cong Tao, Jianfei Pan, Lilan Zhang, Lulu Liu, Ying Zhao, Yiping Fan, Chunwei Cao, Jiali Liu, Jin Zhang, Sin Man Lam, Guanghou Shui, Wanzhu Jin, Wei Li, Jianguo Zhao, Kui Li, Yanfang Wang
Publikováno v:
Protein & Cell, Vol 12, Iss 6, Pp 475-492 (2020)
Abstract RNF20, an E3 ligase critical for monoubiquitination of histone H2B at lysine 120 (H2Bub), has been implicated in the regulation of various cellar processes; however, its physiological roles in adipocytes remain poorly characterized. Here, we
Externí odkaz:
https://doaj.org/article/99303c0053aa495e952c31c70b879b6f
Autor:
Jun Lin, Xiaoxiao Jiang, Meng Dong, Xiaomeng Liu, Qiwei Shen, Yuanyuan Huang, Hanlin Zhang, Rongcai Ye, Huiqiao Zhou, Chunlong Yan, Shouli Yuan, Xiangnan Wu, Li Chen, Yanfang Wang, Min He, Yi Tao, Zhaoyun Zhang, Wanzhu Jin
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract Intermittent fasting (IF), as a dietary intervention for weight loss, takes effects primarily through increasing energy expenditure. However, whether inter‐organ systems play a key role in IF remains unclear. Here, a novel hepatokine, preg
Externí odkaz:
https://doaj.org/article/d27d8f679cf9413db59d782590a7fc98
Autor:
Rongcai Ye, Chunlong Yan, Huiqiao Zhou, Yuanyuan Huang, Meng Dong, Hanlin Zhang, Xiaoxiao Jiang, Shouli Yuan, Li Chen, Rui Jiang, Ziyu Cheng, Kexin Zheng, Qiaoli Zhang, Wanzhu Jin
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Polycystic ovary syndrome (PCOS) is a common endocrine disease accompanied by energetic metabolic imbalance. Because the etiology of PCOS is complex and remains unclear, there is no effective and specific treatment for PCOS. It is often accompanied b
Externí odkaz:
https://doaj.org/article/fd8177c8482640b081b423bd6137f4a0
Autor:
Li Li, Baoguo Li, Min Li, Chaoqun Niu, Guanlin Wang, Ting Li, Elżbieta Król, Wanzhu Jin, John R. Speakman
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1198-1211 (2017)
Objective: Previous work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they
Externí odkaz:
https://doaj.org/article/6c68b78957164e4e89267883dd1a1a5a
Autor:
Lu Yao, Xiaona Cui, Qi Chen, Xiaoying Yang, Fude Fang, Jun Zhang, Guoqing Liu, Wanzhu Jin, Yongsheng Chang
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 641-654 (2017)
Promoting development and function of brown and beige fat may reduce obesity. Here, we show that fat SIRT6 expression is markedly induced by cold exposure and a β-adrenergic agonist. Deletion of SIRT6 in adipose tissue impairs the thermogenic functi
Externí odkaz:
https://doaj.org/article/0de83c3e97b0443abae8162be9adb1fd
Publikováno v:
Biotechnology Letters. 44:1149-1162
We constructed a recombinant oral GLP-1 analogue in Lactococcus lactis (L. lactis) and evaluated its physiological functions.In silico docking suggested the alanine at position 8 substituted with serine (A8SGLP-1) reduced binding of DPP4, which trans