Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Wan-Sung Choi"'
Autor:
Seong-Jae Kim, Min-Jun Kim, Mee-Young Choi, Yoon-Sook Kim, Ji-Myong Yoo, Eun-Kyung Hong, Sunmi Ju, Wan-Sung Choi
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 8, Pp 1203-1211 (2017)
AIM: To investigate the role of O-GlcNAcylation of nuclear factor-kappa B (NF-κB) in retinal ganglion cell (RGC) death and analysedthe effect of Aralia elata (AE) on neurodegeneration in diabetic mice. METHODS: C57BL/6mice with streptozotocin-induc
Externí odkaz:
https://doaj.org/article/a3264ab8e18c49508457b23edf6e5277
Autor:
Seong-Jae Kim, Hwajin Kim, Jeongsook Park, Inyoung Chung, Hyug-Moo Kwon, Wan-Sung Choi, Ji-Myong Yoo
Publikováno v:
International Journal of Ophthalmology, Vol 7, Iss 6, Pp 935-940 (2014)
AIM:To studythe contribution of tonicity response element binding protein (TonEBP) in retinal ganglion cell (RGC) death of diabetic retinopathy (DR).METHODS:Diabetes was induced in C57BL/6 mice by five consecutive intraperitoneal injections of 55 mg/
Externí odkaz:
https://doaj.org/article/352fd6776dcf4f7184c5311e3e3d0d2a
Autor:
Han Ju Lee, Jeong Kyu Shin, Mee Young Choi, Wan Sung Choi, Yoon Sook Kim, Sang Soo Kang, Minjun Kim
Publikováno v:
Molecules and Cells
DNA methylation, and consequent down-regulation, of tumour suppressor genes occurs in response to epigenetic stimuli during cancer development. Similarly, human oncoviruses, including human papillomavirus (HPV), up-regulate and augment DNA methyltran
Publikováno v:
Journal of the Korean Ophthalmological Society. 62:164-172
Publikováno v:
Biochemical and Biophysical Research Communications. 526:1061-1068
Persistent infection with high-risk strains of human papillomavirus (HPV) is the primary cause of cervical cancer, the fourth most common cancer among women worldwide. Two oncoproteins encoded by the HPV genome, E6 and E7, are required for epigenetic
Autor:
Nilufar Rashidova, Nal Ae Yoon, Gyeong Jae Cho, Wan Sung Choi, Dong Hoon Lee, Gu Seob Roh, Jinhyun Ryu, Juyeong Park, Hyun Joon Kim, Joo Yeon Jeong, Sang Soo Kang
Publikováno v:
Development & Reproduction
In many cases, obesity is associated with metabolic disorders. Recently, natural compounds that may be beneficial for improving obesity have received increasing attention. Bitter melon has received attention as a diabetes treatment. NAD+-dependent de
Autor:
Ji Hyeong Baek, Wan Sung Choi, Arul Vignesh, Hyeonwi Son, Gyeong Jae Cho, Hyun Joon Kim, Dong Hoon Lee, Sang Soo Kang, Gu Seob Roh
Publikováno v:
Experimental Neurobiology
Chronic immobilization stress (CIS) induces low levels of glutamate (Glu) and glutamine (Gln) and hypoactive glutamatergic signaling in the mouse prefrontal cortex (PFC), which is closely related to the Glu-Gln cycle. A Gln-supplemented diet ameliora
Autor:
Sneha B. Sontakke, Dong Kun Lee, Sang Soo Kang, Wan Sung Choi, Gu Seob Roh, Doo-hyuk Jung, Bok Soon Go, Hye Jin Chung, Gyeong Jae Cho, Dong Hoon Lee, Ji Hyeong Baek, Hyeonwi Son, Hyun Joon Kim
Publikováno v:
Neuropharmacology. 143:143-152
Emerging evidence has shown the low levels of glutamate (Glu) and glutamine (Gln) and the hypoactivity in the cortex of patients with depression. The hypoactivity is closely related with low frequency of glutamatergic signaling that is affected by th
Autor:
Gyeong Jae Cho, Yoon Sook Kim, Hyun Joon Kim, Mee Young Choi, Wan Sung Choi, Minjun Kim, Sang Soo Kang, Eun-Kyung Hong, Gu Seob Roh, Dong Hoon Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 503:1307-1314
Oxidative stress plays an important role in the development of diabetic retinopathy. Here, we examined whether α-lipoic acid (α-LA), a natural antioxidant, attenuated retinal injury in diabetic mice. The α-LA was orally administered to control mic
Autor:
Seong-Jae Kim, Gyeong Jae Cho, Hyun Joon Kim, Sang Soo Kang, Mee Young Choi, Ji-Myong Yoo, Wan Sung Choi, Dong Hoon Lee, Yoon Sook Kim, Gu Seob Roh, Minjun Kim
Publikováno v:
Biochemical and Biophysical Research Communications. 492:397-403
Retinal degeneration is an early feature of diabetic retinopathy, the major cause of blindness in the developed world. Here we investigated how the widely used antidiabetic drug metformin reduces retinal injury in diabetic mice. Metformin was orally