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pro vyhledávání: '"Wan-Jhu Liao"'
Autor:
Wan-Jhu Liao, 廖婉竹
107
Huntington’s disease (HD), a dominantly inherited neurodegenerative disease, is caused by abnormal expansion of CAG trinucleotide repeats in the exon 1 of the huntingtin (HTT) gene. The most striking pathological feature is the degeneratio
Huntington’s disease (HD), a dominantly inherited neurodegenerative disease, is caused by abnormal expansion of CAG trinucleotide repeats in the exon 1 of the huntingtin (HTT) gene. The most striking pathological feature is the degeneratio
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/t56538
Autor:
Ning Deng, Yun-Yun Wu, Yanan Feng, Wen-Chieh Hsieh, Jen-Shin Song, Yu-Shiuan Lin, Ya-Hsien Tseng, Wan-Jhu Liao, Yi-Fan Chu, Yu-Cheng Liu, En-Cheng Chang, Chia-Rung Liu, Sheh-Yi Sheu, Ming-Tsan Su, Hung-Chih Kuo, Stanley N. Cohen, Tzu-Hao Cheng
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Earlier work has shown that siRNA-mediated reduction of the SUPT4H or SUPT5H proteins, which interact to form the DSIF complex and facilitate transcript elongation by RNA polymerase II (RNAPII), can decrease expression of mutant gene alleles containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9697f58c0a4f89709daec52505070a
https://doi.org/10.1073/pnas.2204779119
https://doi.org/10.1073/pnas.2204779119
