Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Wan-Geun La"'
Autor:
Hee Seok Yang, Ga Hee Kim, Wan-Geun La, Suk Ho Bhang, Tae-Jin Lee, Jong Ho Lee, Byung-Soo Kim
Publikováno v:
Cell Transplantation, Vol 20 (2011)
Recent studies have demonstrated the existence of osteoblast progenitor cells in circulating blood. Here we show that local delivery of bone morphogenetic protein-2 (BMP-2) to cell transplantation sites induces in situ osteogenic differentiation of t
Externí odkaz:
https://doaj.org/article/52a2571127d94eedb95d7cbde57d89a2
Publikováno v:
Journal of materials chemistry. B. 3(42)
Growth factors have been used to regenerate specific tissue structures by stimulating proliferation and migration of target cells, as well as regulating differentiation of various stem cells. To improve tissue regeneration, growth factors need effect
Autor:
Min Sung Kim, Hong Nam Kim, Byung-Soo Kim, Noo Li Jeon, Suk Ho Bhang, Jaesur Oh, Jin Han, Wan-Geun La, Gun-Jae Jeong, Ju-Ro Lee, Seokyung Kang, Jeong-Kee Yoon, Jung-Youn Shin
Publikováno v:
Tissue Engineering Part A. 22:654-664
The rapid recruitment of osteoblasts in bone defects is an essential prerequisite for efficient bone repair. Conventionally, osteoblast recruitment to bone defects and subsequent bone repair has been achieved using growth factors. Here, we present a
Autor:
Hee Seok Yang, Wan-Geun La, Soo-Hong Lee, Heungsoo Shin, Min Suk Lee, Jun Sung Oh, Sajeesh Kumar, Hae In Choi
Publikováno v:
Macromolecular Research. 24:385-391
Skin flaps have the crucial issue that skin necrosis can occur due to tissue ischemia in the distal parts of flaps. To prevent tissue necrosis, skin flaps need to be supplied with sufficient blood perfusion through quick vascularization in the ischem
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:594-604
Nanoscale topography substrates have potential in guiding cell polarization and migration. Wound healing can be accelerated by nanotopographical substrates which provided appropriate direction to host cells around wound site. We fabricated biodegrada
Autor:
Myungkyung Noh, Wan-Geun La, Jin Han, Minyoung Yi, Suk Ho Bhang, Woo-Sik Kim, Yunhee Kim Kwon, Taekyung Yu, Hyeon-Ki Jang, Byung-Soo Kim
Publikováno v:
Biomaterials. 55:33-43
At high concentrations, manganese (Mn) promotes cellular neurodevelopment but causes toxicity. Here, we report that Mn ion at high concentrations can be delivered to pheochromocytoma 12 (PC12) cells using gold nanoparticles (AuNPs) to enhance cellula
Autor:
Suk Ho Bhang, Seahyoung Lee, Min Jin, Jooyeon Park, Hyeon-Ki Jang, Jung-Youn Shin, Seokyung Kang, Byung-Soo Kim, Seong-Seo Noh, Yoon-Ji Ma, Wan-Geun La
Publikováno v:
Tissue Engineering Part A. 21:1275-1287
Implantation of ex vivo expanded and osteogenically differentiated mesenchymal stem cells (MSCs) for bone regeneration has drawbacks for clinical applications, such as poor survival of implanted cells and increased treatment expenses. As a new approa
Autor:
Wan-Geun La, Byung-Soo Kim, Byung Hee Hong, Myungkyung Noh, Seungmi Ryu, Tae-Jin Lee, Jong Bo Park, Suk Ho Bhang, Seokyung Kang
Publikováno v:
Carbon. 83:162-172
Mesenchymal stem cells (MSCs) preferentially differentiate to osteogenic lineage when cultured on mechanically stiff substrates. However, collagen sponges, clinically approved scaffolds for bone regeneration, provide soft microenvironment to MSCs. He
Autor:
Wan-Geun La, Hee Seok Yang
Publikováno v:
Tissue Engineering and Regenerative Medicine. 12:20-27
Tube formation by endothelial cells (EC) is a one of the key factors involved in initial revascularization during the tissue regeneration process. Several previous studies suggested that EC tube formation can be regulated by the stiffness of the cult
Autor:
Hyeon-Ki Jang, Tae-Jin Lee, Suk Ho Bhang, Hee-Hun Yoon, Moon-Joo Jung, Jung-Youn Shin, Byung-Soo Kim, Wan-Geun La, Jeong-Kee Yoon
Publikováno v:
Carbon. 78:428-438
High doses of bone morphogenetic protein-2 (BMP-2) are required for effective bone regeneration. However, these high doses often cause undesirable adverse effects, including bone overgrowth, osteolysis, and activation of the immune response, and rais