Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Wan Wan Lin"'
Autor:
Anthony Yan-Tang Wu, Ponarulselvam Sekar, Duen-Yi Huang, Shu-Hao Hsu, Chi-Ming Chan, Wan-Wan Lin
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-19 (2023)
Abstract Background Although stimulating autophagy caused by UV has been widely demonstrated in skin cells to exert cell protection, it remains unknown the cellular events in UVA-treated retinal pigment epithelial (RPE) cells. Methods Human ARPE-19 c
Externí odkaz:
https://doaj.org/article/354079cb51af4366ab24536d0ce24e74
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 481 (2024)
The activation of microglia and the production of cytokines are key factors contributing to progressive neurodegeneration. Despite the well-recognized neuronal programmed cell death regulated by microglial activation, the death of microglia themselve
Externí odkaz:
https://doaj.org/article/b4b4510eaede40a1a099efea7e1b142c
Autor:
Keith Jun Hao Cheong, Duen-Yi Huang, Ponarulselvam Sekar, Rou Jhen Chen, Irene Han-Juo Cheng, Chi-Ming Chan, Yuan-Shen Chen, Wan-Wan Lin
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 343 (2024)
Calcium/calmodulin-dependent serine protein kinase (CASK) is a scaffold protein and plays critical roles in neuronal synaptic formation and brain development. Previously, CASK was shown to associate with EGFR to maintain the vulval cell differentiati
Externí odkaz:
https://doaj.org/article/4c40b099beaf432193048d5d34ad2f63
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102786- (2023)
Diabetic retinopathy (DR) is a major cause of blindness in adult, and the accumulation of advanced glycation end products (AGEs) is a major pathologic event in DR. Methylglyoxal (MGO), a highly reactive dicarbonyl compound, is a precursor of AGEs. Al
Externí odkaz:
https://doaj.org/article/c84d97ed192148468c6ef32e82592307
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
P2X7 signaling has been explored in adipose tissue because of its potential to promote ATP-activated inflammatory cascades during obesogenic environments. However, limited literature has investigated the role of the P2X7 receptor in lipid metabolism
Externí odkaz:
https://doaj.org/article/879dc29c152f42809272d3e176c7c612
Autor:
Hyemin Lee, Duen-Yi Huang, Hua-Ching Chang, Chia-Yee Lin, Wan-Yu Ren, Yang-Shia Dai, Wan-Wan Lin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
B lymphocyte-induced maturation protein-1 (Blimp-1) is a transcriptional repressor and plays a crucial role in the regulation of development and functions of various immune cells. Currently, there is limited understanding about the regulation of Blim
Externí odkaz:
https://doaj.org/article/867f9b8541524bf0b7a70cc0028ef602
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 141 (2023)
Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO3) is an oxidative toxic agent, and its retinal toxicity has been used as the model of dry age-relat
Externí odkaz:
https://doaj.org/article/7ff622d90f5049e6a4740880d8190825
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-4 (2019)
After the publication of this article [1], the authors would like to clarify that some immunoblotting data in Figs. 2f, 3a and 4b were obtained from the same samples but individual SDS-PAGE gels.
Externí odkaz:
https://doaj.org/article/14f4f91c2c8c43a4ad226ff69462f2ae
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-11 (2019)
Abstract Background Oxidative stress is a major factor in retinal pigment epithelium (RPE) cells injury that contributes to age-related macular degeneration (AMD). NaIO3 is an oxidative toxic agent and its selective RPE cell damage makes it as a repr
Externí odkaz:
https://doaj.org/article/b1e923fd208145fabc11bce47aa4e1e0
Autor:
Yi-Gen Pan, Ming-Ting Huang, Ponarulselvam Sekar, Duen-Yi Huang, Wan-Wan Lin, Shie-Liang Hsieh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Gout is a common inflammatory arthritis caused by the deposition of monosodium urate (MSU) crystals in the joints. This activates the macrophages into a proinflammatory state by inducing NLRP3-dependent interleukin-1β (IL-1β) secretion, resulting i
Externí odkaz:
https://doaj.org/article/8b5798b820354f5dae64ba9ce4050533