Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells.

Autor: Baugh R; Department of Oncology, University of Oxford, Oxford, UK., Khalique H; Department of Oncology, University of Oxford, Oxford, UK., Page E; Department of Oncology, University of Oxford, Oxford, UK., Lei-Rossmann J; Department of Oncology, University of Oxford, Oxford, UK., Wan PK; Department of Oncology, University of Oxford, Oxford, UK., Johanssen T; Target Discovery Institute, University of Oxford Nuffield Department of Medicine, Oxford, UK., Ebner D; Target Discovery Institute, University of Oxford Nuffield Department of Medicine, Oxford, UK., Ansorge O; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Seymour LW; Department of Oncology, University of Oxford, Oxford, UK len.seymour@oncology.ox.ac.uk.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 May 09; Vol. 12 (5). Date of Electronic Publication: 2024 May 09.

Automated infection risks assessments (AIRa) for decision-making using a blockchain-based alert system: A case study in a representative building.

Autor: Wan PK; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway., Huang L; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway. Electronic address: lizhen.huang@ntnu.no., Lai Z; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway., Liu X; Department of Technology, Management and Economic, Technical University of Denmark, Copenhagen, Denmark., Nowostawski M; Department of Computer Science, Norwegian University of Science and Technology, Gjøvik, Norway., Holtskog H; Department of Industrial Economics and Technology Management, Norwegian University of Science and Technology, Gjøvik, Norway., Liu Y; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway.

Publikováno v: Environmental research [Environ Res] 2023 Jan 01; Vol. 216 (Pt 3), pp. 114663. Date of Electronic Publication: 2022 Oct 29.

Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus.

Autor: Wan PK; Department Oncology, University of Oxford, Oxford OX3 7DQ, UK., Ryan AJ; Department Oncology, University of Oxford, Oxford OX3 7DQ, UK., Seymour LW; Department Oncology, University of Oxford, Oxford OX3 7DQ, UK. Electronic address: len.seymour@oncology.ox.ac.uk.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 May 05; Vol. 29 (5), pp. 1668-1682. Date of Electronic Publication: 2021 Apr 19.

HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancer.

Autor: Wan PK; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Leung TH; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Siu MK; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Mo XT; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Tang HW; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Chan KK; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Cheung AN; Department of Pathology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China., Ngan HY; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region of China. Electronic address: hysngan@hku.hk.

Publikováno v: Cancer letters [Cancer Lett] 2021 Jan 28; Vol. 497, pp. 14-27. Date of Electronic Publication: 2020 Sep 30.

Reducing Alert Fatigue by Sharing Low-Level Alerts With Patients and Enhancing Collaborative Decision Making Using Blockchain Technology: Scoping Review and Proposed Framework (MedAlert).

Autor: Wan PK; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway., Satybaldy A; Department of Computer Science, Norwegian University of Science and Technology, Gjøvik, Norway., Huang L; Department of Manufacturing and Civil Engineering, Norwegian University of Science and Technology, Gjøvik, Norway., Holtskog H; Department of Industrial Economics and Technology Management, Norwegian University of Science and Technology, Gjøvik, Norway., Nowostawski M; Department of Computer Science, Norwegian University of Science and Technology, Gjøvik, Norway.

Publikováno v: Journal of medical Internet research [J Med Internet Res] 2020 Oct 28; Vol. 22 (10), pp. e22013. Date of Electronic Publication: 2020 Oct 28.