Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wan Fen Li"'
Autor:
Ming-Chen Yang, Chun-Chung Wang, Wei-Chien Tang, Kuan-Ming Chen, Chu-Ying Chen, Hsiao-Han Lin, Yin-Cheng Hsieh, Nan-Hsuan Wang, Yin-Chieh Kuo, Ping-Tzu Chu, Hsin-Yi Tung, Yi-Chen Wu, Juo-Ling Sun, Sheng-Yu Liu, Wan-Fen Li, Wei-Han Lee, Jiann-Shiun Lai, Michael Chang, Ming-Tain Lai
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283473 (2023)
SARS-CoV-2 pandemic has profound impacts on human life and global economy since the outbreak in 2019. With the new variants continue to emerge with greater immune escaping capability, the protectivity of the available vaccines is compromised. Therefo
Externí odkaz:
https://doaj.org/article/6fb17c9ac64c44429bdf1cbbdafd9f89
Autor:
Ming-Tain Lai, Cheng-Der Yu, Jiann-Shiun Lai, Nan-Hsuan Wang, Yueh-Chin Wu, Chi-Huan Lu, Hui-Wen Chang, Yu-Jung Chen, Teng-Yi Huang, I-Ju Chen, Chun-Chung Wang, Wan-Fen Li, Chi-Sheng Shia, Ming-Chen Yang
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcba16014f579e89354c9b3b53f5503c
https://doi.org/10.1158/1535-7163.22522797
https://doi.org/10.1158/1535-7163.22522797
Autor:
Ming-Tain Lai, Cheng-Der Yu, Jiann-Shiun Lai, Nan-Hsuan Wang, Yueh-Chin Wu, Chi-Huan Lu, Hui-Wen Chang, Yu-Jung Chen, Teng-Yi Huang, I-Ju Chen, Chun-Chung Wang, Wan-Fen Li, Chi-Sheng Shia, Ming-Chen Yang
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec703d5b83c795ac018834b8be04b3f
https://doi.org/10.1158/1535-7163.22522800
https://doi.org/10.1158/1535-7163.22522800
Publikováno v:
Journal of Biomimetics, Biomaterials and Biomedical Engineering. 56:1-16
Nanomedicine has been used in tumor treatment and research due to its advantages of targeting, controlled release and high absorption rate. Silver nanoparticle (AgNPs), with the advantages of small particle size, and large specific surface area, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d8815e8c3ea023ec8e6a7f2bacf4c3
https://doi.org/10.4028/p-s8bc3p
https://doi.org/10.4028/p-s8bc3p
Publikováno v:
Molecules, Vol 26, Iss 7, p 1949 (2021)
In this study, the optimum synthetic process of the Pyracantha polysaccharide-iron (PPI) complex was studied via response surface methodology (RSM). Its antioxidant and anti-cancer activities were also investigated. It was demonstrated that the optim
Externí odkaz:
https://doaj.org/article/a3bafdb8c80c48d4871a7276ed05fb4c
Autor:
Daniel Seung Kim, Amber A. Burt, Jane E. Ranchalis, Simona Vuletic, Tomas Vaisar, Wan-Fen Li, Elisabeth A. Rosenthal, Weijiang Dong, Jason F. Eintracht, Arno G. Motulsky, John D. Brunzell, John J. Albers, Clement E. Furlong, Gail P. Jarvik
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 7, Pp 1351-1362 (2015)
Recent studies have failed to demonstrate a causal cardioprotective effect of HDL cholesterol levels, shifting focus to the functional aspects of HDL. Phospholipid transfer protein (PLTP) is an HDL-associated protein involved in reverse cholesterol t
Externí odkaz:
https://doaj.org/article/50a74900d86049efa0ff06e02c7afed0
Publikováno v:
Cancer Research. 83:5946-5946
Background: Globo H (GH) is highly expressed in a variety of epithelial tumors with a limited expression in normal tissues rendering it a novel therapeutic target. OBI-999 is an antibody drug conjugate (ADC) consisting of a GH-specific monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11a391f62a059f742e00b7d6760c9d0
https://doi.org/10.1158/1538-7445.am2023-5946
https://doi.org/10.1158/1538-7445.am2023-5946
Autor:
Fanying, Meng, Wan-Fen, Li, Donald, Jung, Chun-Chung, Wang, Tianyang, Qi, Chi-Sheng, Shia, Ren-Yu, Hsu, Yin-Cheng, Hsieh, Jianxin, Duan
Publikováno v:
Am J Cancer Res
AST-3424/OBI-3424 (denoted by 3424) is a novel prodrug bis-alkylating agent activated by AKR1C3. AKR1C3 is overexpressed in many types of cancer, particularly in liver, non-small cell lung, gastric, renal and CRPC cancer. Currently 3424 is being stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4787dab5eaeeb98185b253f8d02809f
https://pubmed.ncbi.nlm.nih.gov/34354865
https://pubmed.ncbi.nlm.nih.gov/34354865
Autor:
Chun-Chung Wang, Wan-Fen Li, Chih-Chan Lee, Lu-Tzu Chen, Jhih-Jie Yang, Jiann-Shiun Lai, Ming-Tain Lai
Publikováno v:
Cancer Research. 82:6111-6111
Immunogenic cell death (ICD) involves the activation of cytotoxic T lymphocyte-driven adaptive immunity with long-term immunological memory. OBI-3424 is a highly selective prodrug that is activated by AKR1C3 to release a potent bis-alkylating agent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ea7dff16d7ed1a0ee369de91c95967
https://doi.org/10.1158/1538-7445.am2022-6111
https://doi.org/10.1158/1538-7445.am2022-6111
Autor:
Cheng-Der Yu, Hui-Wen Chang, Chi-Sheng Shia, Teng-Yi Huang, Jiann-Shiun Lai, Yueh-Chin Wu, I-Ju Chen, Wan-Fen Li, Yu-Jung Chen, Nan-Hsuan Wang, Chun-Chung Wang, Chi-Huan Lu, Ming-Tain Lai, Ming-Chen Yang
Publikováno v:
Molecular cancer therapeutics. 20(6)
Globo H (GH), a hexasaccharide, is expressed at low levels in normal tissues but is highly expressed in multiple cancer types, rendering it a promising target for cancer immunotherapy. OBI-999, a novel antibody–drug conjugate, is derived from a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed767633053c25c9adc73bd064e3733
https://pubmed.ncbi.nlm.nih.gov/33722855
https://pubmed.ncbi.nlm.nih.gov/33722855