Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wan C. Tsai"'
Autor:
Robert A. Drongowski, Peter J. Strouse, Samir K. Gadepalli, Ronald B. Hirschl, Wan C. Tsai, Frances A. Farley, Kelly L. Vanderhave, Michelle S. Caird
Publikováno v:
Journal of Pediatric Surgery. 46:77-80
Purpose Vertical expandable prosthetic titanium rib (VEPTR) insertion and expansion has been advocated to increase thoracic volume and pulmonary function in patients with thoracic insufficiency syndrome. We reviewed our experience with VEPTR implanta
Autor:
Katherine S. Young, Victor J. Thannickal, Wan C. Tsai, Jane C. Deng, Kazuhiro Tateda, Marc B. Hershenson, Michael L. Rodriguez, Theodore J. Standiford
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 170:1331-1339
Macrolides exert their effects on the host by modulation of immune responses. In this study, we assessed the therapeutic efficacy of azithromycin in a murine model of mucoid Pseudomonas aeruginosa endobronchial infection. The clearance of Pseudomonas
Autor:
Susan M. Phare, Theodore J. Standiford, Gina H. Chen, Kazuhiro Tateda, Wan C. Tsai, Marc Peters-Golden, Raju C. Reddy, Peter Mancuso
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 281:L537-L543
Prostaglandins of the E series are believed to act as important mediators of several pathophysiological events that occur in sepsis. Studies were performed to evaluate the effect of cyclooxygenase (COX)-2-specific inhibition on the outcome in murine
Autor:
Thomas A. Moore, Raju C. Reddy, Theodore J. Standiford, Kazuhiro Tateda, Keizo Yamaguchi, Wan C. Tsai, Jane C. Deng, Michael W. Newstead, Xianying Zeng, Gina H. Chen
Publikováno v:
Infection and Immunity. 69:2017-2024
The roles of CXC chemokine-mediated host responses were examined with an A/J mouse model ofLegionella pneumophilapneumonia. After intratracheal inoculation of 106CFU ofL. pneumophila, the bacterial numbers in the lungs increased 10-fold by day 2; thi
Autor:
Borna Mehrad, Wan C. Tsai, Michael W. Newstead, Xianying Zeng, Theodore J. Standiford, Robert M. Strieter
Publikováno v:
Infection and Immunity. 68:4289-4296
Pulmonary infection due toPseudomonas aeruginosahas emerged as a leading cause of mortality. A vigorous host response is required to effectively clear the organisms from the lungs. This host defense is dependent on the recruitment and activation of n
Autor:
Borna Mehrad, Robert M. Strieter, Thomas A. Moore, Wan C. Tsai, Sergio A. Lira, Theodore J. Standiford
Publikováno v:
The Journal of Immunology. 163:6086-6094
Invasive pulmonary aspergillosis is a devastating complication of immunosuppression, which occurs in association with neutrophil dysfunction or deficiency. ELR+ CXC chemokines are a subfamily of chemokines that play a critical role in neutrophil chem
Autor:
Wan C. Tsai, Robert M. Strieter, Jodi M. Wilkowski, Kathy A. Bucknell, Marie D. Burdick, Sergio A. Lira, Theodore J. Standiford
Publikováno v:
The Journal of Immunology. 161:2435-2440
A vigorous host response is required to effectively clear pathogenic bacteria from the lungs and is dependent upon the recruitment and activation of neutrophils and macrophages. A family of chemotactic cytokines, referred to as chemokines, have been
Autor:
Jack Gauldie, Steven L. Kunkel, Kathy A. Bucknell, Wan C. Tsai, David A. Zisman, Jodi M. Wilkowski, Theodore J. Standiford, Jonathan L. Bramson, Robert M. Strieter
Publikováno v:
Shock. 8:349-356
The overzealous production of proinflammatory cytokines in sepsis can result in shock, multiorgan dysfunction, and even death. In this study we assessed the role of endogenously produced interleukin (IL)-12 in murine models of endotoxemia and Gram-ne
Autor:
Wan C. Tsai, Kathy A. Bucknell, Jodi M. Wilkowski, Steven L. Kunkel, Theodore J. Standiford, Robert M. Strieter, David A. Zisman
Publikováno v:
Journal of Clinical Investigation. 99:2832-2836
The overzealous production of proinflammatory cytokines in sepsis can result in shock, multiorgan dysfunction, and even death. In this study, we assessed the role of monocyte chemoattractant protein-1 (MCP-1) as a mediator of sepsis in endotoxin-chal
Autor:
Kathy A. Bucknell, Gwo Hsiao Chen, Jodi M. Wilkowski, Theodore J. Standiford, Robert M. Strieter, David A. Zisman, Wan C. Tsai
Publikováno v:
Infection and Immunity. 65:1870-1875
Nitric oxide (NO) has been associated with protection against various parasitic and viral infections and may play a similar role in bacterial infections. We studied the role of NO in host defense against Klebsiella pneumoniae infection in the lung. I