Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Wan‐Yu Chen"'
Autor:
Monika Kumari, Kang-Hao Liang, Shih-Chieh Su, Hsiu-Ting Lin, Yu-Feng Lu, Ming-Jane Wu, Wan-Yu Chen, Han-Chung Wu
Publikováno v:
Vaccines, Vol 12, Iss 7, p 714 (2024)
SARS-CoV-2 new waves are primarily caused by changes to the spike protein (S), which can substantially decrease the efficacy of vaccines. Therefore, we tested several multivalent mRNA-LNP vaccines, targeting the full-length S proteins of different va
Externí odkaz:
https://doaj.org/article/065a807d43ca4f63bb9b8eec1855c9e7
Autor:
Monika Kumari, Shih-Chieh Su, Kang-Hao Liang, Hsiu-Ting Lin, Yu-Feng Lu, Kai-Chi Chen, Wan-Yu Chen, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-11 (2023)
Abstract Background Sequential infections with SARS-CoV-2 variants such as Alpha, Delta, Omicron and its sublineages may cause high morbidity, so it is necessary to develop vaccines that can protect against both wild-type (WT) virus and its variants.
Externí odkaz:
https://doaj.org/article/2150241d8ed84f008d3b9efa8e55f62c
Autor:
Shih-Han Ko, Wan-Yu Chen, Shih-Chieh Su, Hsiu-Ting Lin, Feng-Yi Ke, Kang-Hao Liang, Fu-Fei Hsu, Monika Kumari, Chi-Yu Fu, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harbor diverse spike (S) protein sequences, which can greatly influence the efficacies of therapeutics. Therefore, it would be of great value to develop
Externí odkaz:
https://doaj.org/article/738750f514c14a22a2f66f17d012271e
Autor:
Wan-Yu Chen, Wen-Fang Cheng, Wei-Zen Sun, Yen-Ling Lai, Yu-Li Chen, Han-Wei Lin, Chung-Liang Chien, Jung Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 7 (2023)
Background Expression of immune checkpoints in the tumor microenvironment is one mechanism underlying paclitaxel (PTX) chemoresistance. This study aimed to investigate whether the addition of checkpoint blockade to PTX can improve the therapeutic eff
Externí odkaz:
https://doaj.org/article/69a9f68e37e9462cab7eb4a2ff96e08e
Autor:
I-Jung Lee, Cheng-Pu Sun, Ping-Yi Wu, Yu-Hua Lan, I-Hsuan Wang, Wen-Chun Liu, Joyce Pei-Yi Yuan, Yu-Wei Chang, Sheng-Che Tseng, Szu-I Tsung, Yu-Chi Chou, Monika Kumari, Yin-Shiou Lin, Hui-Feng Chen, Tsung-Yen Chen, Chih-Chao Lin, Chi-Wen Chiu, Chung-Hsuan Hsieh, Cheng-Ying Chuang, Chao-Min Cheng, Hsiu-Ting Lin, Wan-Yu Chen, Fu-Fei Hsu, Ming-Hsiang Hong, Chun-Che Liao, Chih-Shin Chang, Jian-Jong Liang, Hsiu-Hua Ma, Ming-Tsai Chiang, Hsin-Ni Liao, Hui-Ying Ko, Liang-Yu Chen, Yi-An Ko, Pei-Yu Yu, Tzu-Jing Yang, Po-Cheng Chiang, Shang-Te Hsu, Yi-Ling Lin, Chong-Chou Lee, Han-Chung Wu, Mi-Hua Tao
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy. Methods We repo
Externí odkaz:
https://doaj.org/article/f52cdfcd615b49699347c79554e26b54
Autor:
Ruei-Min Lu, Kang-Hao Liang, Hsiao-Ling Chiang, Fu-Fei Hsu, Hsiu-Ting Lin, Wan-Yu Chen, Feng-Yi Ke, Monika Kumari, Yu-Chi Chou, Mi-Hua Tao, Yi-Ling Lin, Han-Chung Wu
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15587- (2023)
The COVID-19 pandemic continues to threaten human health worldwide as new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge. Currently, the predominant circulating strains around the world are Omicron variants, which
Externí odkaz:
https://doaj.org/article/cf78b55bb0294b8882b03e15ebc72703
Autor:
Wan‐Yu Chen, Ku‐Hao Fang, Chun‐Wei Wang, Chun‐Ta Liao, Tzu‐Chen Yen, Taun‐Jen Fang, Shih‐Fan Lai, Hsiang‐Kuang Liang, Bing‐Shen Huang
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 6, Pp 1339-1346 (2021)
Abstract Objective Whether to administer adjuvant treatment is a matter of great debate for oral cavity cancer harboring a single positive node without extranodal extension and positive margin (defined as low/intermediate risk pN1new in this study).
Externí odkaz:
https://doaj.org/article/734f093349734e15b84c6b0efb830f63
Autor:
Kang-Hao Liang, Pao-Yin Chiang, Shih-Han Ko, Yu-Chi Chou, Ruei-Min Lu, Hsiu-Ting Lin, Wan-Yu Chen, Yi-Ling Lin, Mi-Hua Tao, Jia-Tsrong Jan, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-12 (2021)
Abstract Background Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus with a high mutation rate. Importantly, several currently circulating SARS-CoV-2 variants are associated w
Externí odkaz:
https://doaj.org/article/7e765143995640ccb0b25900e804ab12
Autor:
Shih-Chieh Su, Tzu-Jing Yang, Pei-Yu Yu, Kang-Hao Liang, Wan-Yu Chen, Chun-Wei Yang, Hsiu-Ting Lin, Mei-Jung Wang, Ruei-Min Lu, Hsien-Cheng Tso, Meng-Jhe Chung, Tzung-Yang Hsieh, Yu-Ling Chang, Shin-Chang Lin, Fang-Yu Hsu, Feng-Yi Ke, Yi-Hsuan Wu, Yu-Chyi Hwang, I-Ju Liu, Jian-Jong Liang, Chun-Che Liao, Hui-Ying Ko, Cheng-Pu Sun, Ping-Yi Wu, Jia-Tsrong Jan, Yuan-Chih Chang, Yi-Ling Lin, Mi-Hua Tao, Shang-Te Danny Hsu, Han-Chung Wu
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
Development of effective therapeutics for mitigating the COVID-19 pandemic is a pressing global need. Neutralizing antibodies are known to be effective antivirals, as they can be rapidly deployed to prevent disease progression and can accelerate pati
Externí odkaz:
https://doaj.org/article/16354bc5faef45df8f05181199b75656
Autor:
Wan-Yu Chen, Chen-Tu Wu, Chun-Wei Wang, Keng-Hsueh Lan, Hsiang-Kuang Liang, Bing-Shen Huang, Yih-Leong Chang, Sung-Hsin Kuo, Ann-Lii Cheng
Publikováno v:
Radiation Oncology, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract Background Our aim was to investigate the prognostic significance of tumor-infiltrating lymphocytes (TILs) in operable tongue cancer patients. Methods The presence of CD3+, CD4+, CD8+, and forkhead box protein P3-positive (FOXP3+) TILs in tu
Externí odkaz:
https://doaj.org/article/c2054322fc134a16813187c329493458