Výsledky vyhledávání - "Walter van Gils"

Gene expression profiling in uveal melanoma: two regions on 3p related to prognosis

Autor: Wilfred F. J. van IJcken, Hanneke W. Mensink, Annelies de Klein, Gregorius P M Luyten, Hennie T. Brüggenwirth, Elisabeth M. Lodder, Emine Kilic, Nicole C. Naus, Walter van Gils, Dion Paridaens

Publikováno v: Investigative ophthalmology & visual science, 49(10), 4254-4262. Association for Research in Vision and Ophthalmology Inc.
Investigative Ophthalmology & Visual Science, 49(10), 4254-4262. Association for Research in Vision and Ophthalmology Inc.

textabstractPURPOSE. Although studies on uveal melanoma (UM) revealed prognostic significance of chromosomal aberrations, they resulted in classification errors in survival prediction. A robust prognostic classifier with strong predictive value and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6c46211180ec09987eafc15819570e
https://doi.org/10.1167/iovs.08-2033

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Expression of APITD1 is not related to copy number changes of chromosomal region 1p36 or the prognosis of uveal melanoma

Autor: Hanneke W. Mensink, Dion Paridaens, Hennie T. Brüggenwirth, Michael M. Verbiest, Annelies de Klein, Emine Kilic, Jolanda Vaarwater, Walter van Gils, Gregorius P.M. Luyten

Publikováno v: Investigative Ophthalmology & Visual Science, 48(11), 4919-4923. Association for Research in Vision and Ophthalmology Inc.

PURPOSE. Concurrent loss of chromosome arm 1p, region 36, and chromosome 3 leads to decreased disease-free survival in patients with uveal melanoma. A candidate tumor-suppressor gene APITD1 is located on the critical region on chromosome arm 1p, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce0ce441f535024875c40e6ac7cc8d9
https://pure.eur.nl/en/publications/902f31ba-a209-42dc-92fa-784652cb01a6

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Clinical and cytogenetic analyses in uveal melanoma

Autor: Annelies de Klein, Dion Paridaens, Walter van Gils, Marjan E van Til, H. Berna Beverloo, Gregorius P M Luyten, Emine Kilic, Elisabeth M. Lodder, Cornelia M. Mooy

Publikováno v: Investigative ophthalmology & visual science, 47(9), 3703-3707. Association for Research in Vision and Ophthalmology Inc.
Investigative Ophthalmology & Visual Science, 47(9), 3703-3707. Association for Research in Vision and Ophthalmology Inc.

PURPOSE. Uveal melanoma is one of the most frequently occurring primary intraocular malignancies in the Western world. Cytogenetically these tumors are characterized by typical chromosomal losses and gains, such as loss of 1p, 3, and 6q and gain of 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f082dcc9ec5c8c618f4e89cd062b1dd0
https://pure.eur.nl/en/publications/28cb45c9-ce37-4c40-ac73-c089be39c2a7

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Rapid screening of innate immune gene expression in zebrafish using reverse transcription - multiplex ligation-dependent probe amplification

Autor: Annemarie H. Meijer, Herman P. Spaink, Walter van Gils, Derek Butler, Janneke Rotman

Publikováno v: BMC Research Notes, Vol 4, Iss 1, p 196 (2011)
BMC Research Notes

Background With the zebrafish increasingly being used in immunology and infectious disease research, there is a need for efficient molecular tools to evaluate immune gene expression in this model species. RT-MLPA (reverse transcription - multiplex li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7045e310addd6d93f257858f18d0f811
http://www.biomedcentral.com/1756-0500/4/196

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Regional deletion and amplification on chromosome 6 in a uveal melanoma case without abnormalities on chromosomes 1p, 3 and 8

Autor: Marjan E. van Til-Berg, Michael M. Verbiest, Emine Kilic, Gregorius P M Luyten, Annelies de Klein, Walter van Gils, Dion Paridaens, Jolanda Vaarwater, Hennie T. Brüggenwirth, Berna Beverloo

Publikováno v: Melanoma Research, 18(1), 10-15. Lippincott Williams & Wilkins

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Loss of the long arm and gain of the short arm of chromosome 6 are frequently observed chromosomal aberrations in UM, together with loss of chromosome 1p36, loss of chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe6b373762ec5877dbe8c2b9e7ce342
https://pure.eur.nl/en/publications/0d01d19c-de97-4772-b68d-fa9b8afbbb5b

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Concurrent loss of chromosome arm 1p and chromosome 3 predicts a decreased disease-free survival in uveal melanoma patients

Autor: Marjan E van Til, Theo Stijnen, Nicole C. Naus, Walter van Gils, Michael M. Verbiest, Annelies de Klein, Dion Paridaens, Cornelia M. Mooy, Emine Kilic, Caroline C W Klaver, H. Berna Beverloo, Gregorius P M Luyten

Publikováno v: Investigative Ophthalmology & Visual Science, 46(7), 2253-2257. Association for Research in Vision and Ophthalmology Inc.

PURPOSE: Uveal melanoma is a highly malignant disease with a mortality rate of 50% at 10 to 15 years. Previous studies have shown that chromosomal changes are associated with decreased survival of the patient. However, in these studies the small numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ced1fb163a645b1f166398435ea2094
https://pubmed.ncbi.nlm.nih.gov/15980208

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