Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Walter W. Massefski"'
Publikováno v:
Chirality. 22:838-843
By using a combination of inverse gated (1)H decoupled (13)C-NMR experiments1 with short acquisition times and NMR Cryo-probe technology, the sample requirements and experimental times necessary to accurately measure enantiomeric excess of small chir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292efa64b869e8721ad7165d5b6baa25
https://doi.org/10.1002/chir.20844
https://doi.org/10.1002/chir.20844
Autor:
Guillermo Moyna, Richard P. Swatloski, Gonzalo Hernandez, Walter W. Massefski, Richard C. Remsing, Robin D. Rogers
Publikováno v:
The Journal of Physical Chemistry B. 112:11071-11078
The solvation of carbohydrates in N, N'-dialkylimidazolium ionic liquids (ILs) was investigated by means of 13C and 35/37Cl NMR relaxation and 1H pulsed field gradient stimulated echo (PFG-STE) diffusion measurements. Solutions of model sugars in 1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a16324c18ee8ab5c95e101d2d0c085a
https://doi.org/10.1021/jp8042895
https://doi.org/10.1021/jp8042895
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 13:73-78
We have designed and implemented a computer application called CHECKIN to submit open-access NMR data to the Wyeth Research compound validation and registration workflow process. At Wyeth Research, all analytical data used for compound validation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c06d48c25e7bfde52817d7887f6a0c4
https://doi.org/10.1016/j.jala.2007.10.003
https://doi.org/10.1016/j.jala.2007.10.003
Publikováno v:
Synlett. 2009:2518-2520
The direct trifluoromethylation of nitriles using TMSCF 3 is reported. This reaction is promoted by TBABF and provides α,α-bistrifluoromethylated amines in moderate to good yields. The reaction conditions are mild and tolerate a range of functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612a26c7d5932b9250c834f7381947c7
https://doi.org/10.1055/s-0029-1217824
https://doi.org/10.1055/s-0029-1217824
Publikováno v:
Journal of the American Chemical Society. 119:1594-1598
The structure elucidations of new fungal products CP-225,917 and CP-263,114 are described. The structures, including relative stereochemistry, were established using a variety of analytical data and extensive NMR analysis. The compounds possess a bic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9afda248a58301fa993a6d08f0783cac
https://doi.org/10.1021/ja961000v
https://doi.org/10.1021/ja961000v
Synthesis of potent and orally efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitor HSD-016
Autor:
Huan-Qiu Li, S. Mansour Tarek, Zhao-Kui Wan, Wang Youchu, Walter W. Massefski, Christopher Kendall, Eddine Saiah, Stéphane Gingras, Jason Shaoyun Xiang, Eva Chenail
Publikováno v:
The Journal of organic chemistry. 76(17)
Cortisol and the glucocorticoid receptor (GR) signaling pathway has been linked to the development of diabetes and metabolic syndrome. In vivo, 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive cortisone to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868770b148a0df4e220fa5088eff40dd
https://pubmed.ncbi.nlm.nih.gov/21736359
https://pubmed.ncbi.nlm.nih.gov/21736359
Publikováno v:
ChemInform. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f548eeac88113427dfe343ac4c5b07
https://doi.org/10.1002/chin.201004056
https://doi.org/10.1002/chin.201004056
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d05dd9c0a490d60b66f8f3b6e0fe2e83
https://doi.org/10.1002/chin.200812056
https://doi.org/10.1002/chin.200812056
Autor:
Brian A. Provencher, Walter W. Massefski, John C. McKew, Gregory M. Ciszewski, Arthur Lee, Stephen D. Huhn, Derek Cecil Cole, Lori Krim Gavrin
Publikováno v:
The Journal of organic chemistry. 72(3)
This work describes two distinct routes to prepare pyrazolo[1,5-alpha]pyrimidin-7-ones and two distinct routes to prepare pyrazolo[1,5-alpha]pyrimidin-5-ones. Use of 1,3-dimethyluracil as the electrophile in the preparation of the pyrimidin-5-one reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d428b2e061f71a58c8473e80bf9da0
https://pubmed.ncbi.nlm.nih.gov/17253833
https://pubmed.ncbi.nlm.nih.gov/17253833
Autor:
Leonard G. Contillo, Janice C. Parker, Ralph W. Stevenson, Glenn C. Andrews, Jane M. Withka, Walter W. Massefski, David H. Singleton, Kim M. Andrews
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
Glucagon-like peptide-1 (GLP-1) is an effective insulin secretagogue with sustained efficacy, with therapeutic potential in treating diabetes [1], As a result there has been much interest is determining its’ receptor bound conformation for rational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa67974d3f033e121416bd35eeac493
https://doi.org/10.1007/0-306-46881-6_267
https://doi.org/10.1007/0-306-46881-6_267
