Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Walter Wörner"'
Publikováno v:
European journal of biochemistry. 205(3)
1. Dihydrodiol dehydrogenase activities were investigated in rabbit liver. Using a five-step purification scheme, eight isoenzymes of dihydrodiol dehydrogenase with isoelectric points of 5.55-9.3 and promoter molecular masses of 34-35 kDa were purifi
Autor:
Frans Setiabudi, Karl L. Platt, Walter Wörner, Jochen Klein, Franz Oesch, Karin Post, Helmut Thomas, Heinz Frank
Publikováno v:
Chemico-biological interactions. 76(2)
Rat liver dihydrodiol dehydrogenase (DDH, EC 1.3.1.20) has been shown to reduce the mutagenicity of benz[ a ]anthracene (BA) in the bacterial Ames test. BA-3,4-dihydrodiol is a highly mutagenic and tumorigenic metabolite of BA. In order to test the h
Publikováno v:
Biochemical and Biophysical Research Communications. 107:959-965
Elongation factor Tu (EF-Tu) of Streptoverticillium mobaraense , which produces pulvomycin, has been prepared to 90% purity. The purified protein differs significantly from the analogous protein found in Escherichia coli in molecular weight and antib
Autor:
Walter Wörner, Heinz Wolf
Publikováno v:
FEBS Letters. (2):322-326
Properties of the elongation factor Tu from Lactobacillus brevis which is naturally insensitive to kirromycin are described. The protein is characterized by an unusual nucleotide-binding site with increased affinity for GTP and extreme heat stability
Autor:
Walter Wörner, Franz Oesch
Publikováno v:
FEBS Letters. (2):263-267
Dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase activity in rat and rabbit liver cytosol have been analyzed by isoelectric focussing and subsequent activity staining. Identity of the two enzymes in rat liver cytosol is demonstrated
Publikováno v:
Biological Reactive Intermediates III ISBN: 9781468451368
Rat liver microsomal and cytosolic epoxide hydrolase may be distinguished through differences in substrate specificity: styrene 7,8-oxide is preferentially hydrolyzed by the microsomal form, while trans-stilbene oxide is the prefered substrate for cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54031ee739354cbd5a336345162de1c8
https://doi.org/10.1007/978-1-4684-5134-4_16
https://doi.org/10.1007/978-1-4684-5134-4_16
Publikováno v:
European journal of biochemistry. 176(1)
Rat liver cytosolic epoxide hydrolase has been purified and characterized. The enzyme was purified from tiadenol-induced rat liver 540-fold with respect to trans-stilbene oxide as a substrate. Similar purification was obtained with the substrates tra
Publikováno v:
IUPHAR 9th International Congress of Pharmacology London 1984 ISBN: 9780333371367
Xenobiotic compounds are commonly rather nontoxic as such, but if they are lipophilic tend to accumulate in body tissues. The compounds must therefore be transformed to water-soluble metabolites in order to be excreted: in this process, reactive inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01aa1bfbf0a61812db305550c43a5ba2
https://doi.org/10.1007/978-1-349-17615-1_34
https://doi.org/10.1007/978-1-349-17615-1_34
Autor:
Christopher Timms, Walter Wörner, P Dostert, Renate Hartmann, M. Strolin-benedetti, Franz Oesch, Ludwig Schladt
Publikováno v:
Biochemical pharmacology. 36(3)
The effects of two cholesterol-lowering (probucol and 1-benzyl-imidazole), three triglycerideand cholesterol-lowering (clofibrate, tiadenol and fenofibrate) and one triglyceride-lowering (acetylsalicylic acid) compounds on the specific activities of
Autor:
M. Strolin-Benedetti, Ch. Timms, P. Dostert, Ludwig Schladt, Walter Wörner, Franz Oesch, Renate Hartmann
Publikováno v:
Journal of cancer research and clinical oncology. 114(4)
Fischer-344 rats and Hartley guinea pigs received a diet containing 0.01% (w/w), 0.05% (w/w), or 0.25% (w/w) of the hypolipidemic drug fenofibrate. Rats were treated for 4, 7, 14, or 21 days, and a clear dose-dependent and weak time-dependent increas