Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Walter Volknandt"'
Autor:
Jens Weingarten, Melanie Laßek, Benjamin F. Mueller, Marion Rohmer, Dominic Baeumlisberger, Benedikt Beckert, Jens Ade, Patricia Gogesch, Amparo Acker-Palmer, Michael Karas, Walter Volknandt
Publikováno v:
Proteomes, Vol 3, Iss 2, Pp 74-88 (2015)
Neurotransmitter release as well as structural and functional dynamics at the presynaptic active zone (PAZ) comprising synaptic vesicles attached to the presynaptic plasma membrane are mediated and controlled by its proteinaceous components. Here we
Externí odkaz:
https://doaj.org/article/b8d1293d2bdc4cdf8fbe0dc83f95f3e0
Publikováno v:
Proteomes, Vol 2, Iss 2, Pp 243-257 (2014)
The proteome of the presynaptic active zone controls neurotransmitter release and the short- and long-term structural and functional dynamics of the nerve terminal. The proteinaceous inventory of the presynaptic active zone has recently been reported
Externí odkaz:
https://doaj.org/article/ae06447567c24c70bc4dd93bda1fbf81
Autor:
Melanie Laßek, Jens Weingarten, Martin Wegner, Benjamin F Mueller, Marion Rohmer, Dominic Baeumlisberger, Tabiwang N Arrey, Meike Hick, Jörg Ackermann, Amparo Acker-Palmer, Ina Koch, Ulrike Müller, Michael Karas, Walter Volknandt
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004832 (2016)
The hallmarks of Alzheimer's disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of hi
Externí odkaz:
https://doaj.org/article/12eaa764d02a488986ca2d8a8ced81be
Aβ42 oligomers impair the bioenergetic activity in hippocampal synaptosomes derived from APP-KO mice
Publikováno v:
Biological Chemistry
Employing hippocampal synaptosomes from amyloid precursor protein (APP)-deleted mice we analyzed the immediate effects of amyloid beta peptide 42 (Aβ42) peptide in its oligomeric or fibrillar assembly or of soluble amyloid precursor protein alpha (s
Publikováno v:
Arthropod Structure & Development. 47:74-81
For providing their offspring females of the digger wasp species Ampulex compressa hunt cockroaches, paralyze them and attach as a rule one egg to the coxa of one of the mid legs of their prey. We observed the egg-laying behavior and examined with li
Autor:
Lisa Waberer, Erik Henrich, Volker Dötsch, Nina Morgner, Walter Volknandt, Frank Bernhard, Oliver Peetz
Publikováno v:
Journal of Neurochemistry. 140:280-293
The integral synaptic vesicle protein SV31 has been shown to bind divalent cations. Here we demonstrate that SV31 protein synthesized within a cell-free system binds Zn2+ and to a lower extent Ni2+ and Cu2+ ions. Expression with Zn2+ stabilized the p
Publikováno v:
Arthropod Structure & Development. 44:491-507
The digger wasp species Ampulex compressa produces its venom in two branched gland tubules. They terminate in a short common duct, which is bifurcated at its proximal end. One leg is linked with the venom reservoir, the other one extends to the ductu
Publikováno v:
Frontiers in Molecular Neuroscience
The amyloid precursor protein (APP) was discovered in the 1980s as the precursor protein of the amyloid A4 peptide. The amyloid A4 peptide, also known as A-beta (Aβ), is the main constituent of senile plaques implicated in Alzheimer`s disease (AD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2e2ed3bcea03e024870f93572fcefe
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43003
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43003
Autor:
Walter Volknandt, Ulrike Müller, Ina Koch, Benedikt Beckert, Martin Wegner, Amparo Acker-Palmer, Jens Weingarten, Eva Harde, Michael Karas, Moritz Neupärtl, Jörg Ackermann, Vahid Golghalyani, Melanie Laßek, Tabiwang N. Array
Publikováno v:
Frontiers in Synaptic Neuroscience
Front. Synaptic Neurosci.
Front. Synaptic Neurosci.
Synaptic release sites are characterized by exocytosis-competent synaptic vesicles tightly anchored to the presynaptic active zone (PAZ) whose proteome orchestrates the fast signaling events involved in synaptic vesicle cycle and plasticity. Allocati
Autor:
Melanie Laßek, Jens Weingarten, Marion Rohmer, Ilaria Lunger, Simone Dudek, Walter Volknandt, Benjamin F. Mueller, Michael Karas, Patricia Gogesch, Dominic Baeumlisberger
Publikováno v:
Molecular and Cellular Neuroscience. 59:106-118
Neurotransmitter release as well as the structural and functional dynamics of the presynaptic active zone is controlled by proteinaceous components. Here we describe for the first time an experimental approach for the isolation of the presynaptic act