Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Walter Tinetto"'
Autor:
Fabian Von Arx, Fergal Casey, Sonja Tobler, Robert Cozens, Ying Liang, En Li, E. Robert McDonald, John Monahan, Audrey Kauffmann, Chao Zhang, Hans Bitter, Daniel Wyss, Mallika Singh, Edward Lorenzana, Tara L. Naylor, Francesco Hofmann, Rebecca Leary, Peter Atadja, Alice Loo, Fiona Xu, Anupama Reddy, Hongbo Cai, Ernesta Dammassa, Margaret E. McLaughlin, Shannon Chuai, Yun Zhang, Fernando Salangsang, Susmita Chatterjee, Christian Schnell, Stephanie Barbe, Hui Gao, Michael Rugaard Jensen, Youzhen Wang, Nicholas Keen, William R. Sellers, Millicent Embry, O. Alejandro Balbin, John Green, Marion Wiesmann, Joseph Lehar, Francesca Santacroce, Guizhi Yang, Claudia Roelli, Scott D. Collins, Kavitha Venkatesan, Colleen Kowal, Hui Qin Wang, Montesa Patawaran, Angad P Singh, Jason Merkin, Juliet Williams, Walter Tinetto, Roberto Velazquez, Emma Lees, Stephane Ferretti, Ronald Meyer, Nicolas Ebel, Shawn Cogan, Joshua M. Korn, David A. Ruddy, Zongyao Wang, Yan Tang, Derek Y. Chiang, Nancy Pryer
Publikováno v:
Nature Medicine. 21:1318-1325
Profiling candidate therapeutics with limited cancer models during preclinical development hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous patient responses for patient-selection strategies. We established
Autor:
Christian Schnell, Walter Tinetto, Thomas Ferrat, Michael Rugaard Jensen, Christine Fritsch, Sonja Tobler, Daniel Wyss
Publikováno v:
Cancer Research. 78:3933-3933
The gene encoding for the catalytic subunit of the phosphatidylinositol-3-kinase (PI3K), p110a (PIK3CA) is the most frequently mutated kinase in cancer. This discovery triggered the development of small molecule anti-PI3K inhibitors, such as NVP-BYL7