Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Walter Sonck"'
Autor:
Vera Rogiers, Miranda Cornet, Karin Mertens, Andre Callaerts, Walter Sonck, Antoine Vercruysse
Publikováno v:
Vrije Universiteit Brussel
The effect of age and gender on the in vitro biotransformation of 2-methylpropene, an alkene metabolized to 2-methyl-1,2-epoxypropane, was studied. The epoxide concentration and the epoxide metabolizing enzymatic activities were investigated in male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da11e44712c30f7fb82e2dc797c2d6c
https://doi.org/10.1016/0047-6374(94)90102-3
https://doi.org/10.1016/0047-6374(94)90102-3
Autor:
R. J. Laib, Antoine Vercruysse, Miranda Cornet, Georg Csanády, Vera Rogiers, Walter Sonck, Andre Callaerts
Publikováno v:
Vrije Universiteit Brussel
Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, adhesives, antioxidants). In this work, the biotrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9705bedbc34289b0c2795618d4af026
https://doi.org/10.1007/bf01968959
https://doi.org/10.1007/bf01968959
Autor:
Antoine Vercruysse, Walter Sonck, Vera Rogiers, Yves Vandenberghe, Andre Callaerts, C.F.A. van Bezooijen, Sandra Coecke, Gino Verleye
Publikováno v:
Mechanisms of Ageing and Development. 55:189-198
Age-associated alterations of hepatic cytosolic glutathione S-transferase activities towards 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene were investigated in Brown Norway rats of both sexes (11-144 weeks old), under control conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f47152fb10e9dad12d54b61c3d6897
https://doi.org/10.1016/0047-6374(90)90026-c
https://doi.org/10.1016/0047-6374(90)90026-c
Publikováno v:
Toxicology in Vitro. 4:439-442
Addition of 2% dimethylsulphoxide (DMSO) to the medium has been described to retain biochemical and morphological differentiation of cultured rat hepatocytes. The maintenance of differentiated hepatocytes for a long time with stable phase I and II bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30530c49d6d52074b9a75f0e5d77f39
https://doi.org/10.1016/0887-2333(90)90096-c
https://doi.org/10.1016/0887-2333(90)90096-c
Publikováno v:
Journal of chromatography. 565(1-2)
A reversed-phase ion-exchange high-performance liquid chromatographic technique, suitable for the separate measurement of reduced (GSH) and oxidized (GSSG) glutathione in cultures of adult rat hepatocytes, is described. A commercially available Nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29810740f23abd09eba22caaba90dc5
https://pubmed.ncbi.nlm.nih.gov/1874863
https://pubmed.ncbi.nlm.nih.gov/1874863
Publikováno v:
Vrije Universiteit Brussel
Reduced and oxidized glutathione contents of adult rat hepatocytes in pure culture and in co-culture with rat epithelial cells were measured under various medium conditions. To the standard medium fetal calf serum, nicotinamide, H2SeO3, dimethylsulph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774df3d4110b541ca2f03cbc60358c40
https://pubmed.ncbi.nlm.nih.gov/1832329
https://pubmed.ncbi.nlm.nih.gov/1832329
Publikováno v:
Vrije Universiteit Brussel
A reversed-phase ion-exchange high-performance liquid chromatographic technique, suitable for the separate measurement of reduced (GSH) and oxidized (GSSG) glutathione in cultures of adult rat hepatocytes, is described. A commercially available Nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9653fb6d999ef518f32e75c5e09856e3
https://biblio.vub.ac.be/vubir/measurements-of-reduced-and-oxidized-glutathione-in-cultures-of-adult-rat-hepatocytes(1c2908b4-5b9c-4cc1-9ac0-c3140d378eb8).html
https://biblio.vub.ac.be/vubir/measurements-of-reduced-and-oxidized-glutathione-in-cultures-of-adult-rat-hepatocytes(1c2908b4-5b9c-4cc1-9ac0-c3140d378eb8).html
Autor:
Sandra Coecke, Yves Vandenberghe, Andre Callaerts, Walter Sonck, Gino Verleye, Bezooyen, C. F. A., Antoine Vercruysse, Vera Rogiers
Publikováno v:
Vrije Universiteit Brussel
Age-associated alterations of hepatic cytosolic glutathione S-transferase activities towards 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene were investigated in Brown Norway rats of both sexes (11-144 weeks old), under control conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c89459f39cad5d25bff0d5e96fe1d0b9
https://biblio.vub.ac.be/vubir/hepatic-cytosolic-gst-activities-in-ageing-brown-norway-rat-importance-of-sex-differences-and-phenobarbital-treatment-for-studie-of-ageing(1b42c18c-9ef6-4611-b64c-a4e41504febb).html
https://biblio.vub.ac.be/vubir/hepatic-cytosolic-gst-activities-in-ageing-brown-norway-rat-importance-of-sex-differences-and-phenobarbital-treatment-for-studie-of-ageing(1b42c18c-9ef6-4611-b64c-a4e41504febb).html
Publikováno v:
Vrije Universiteit Brussel
1. The biotransformation of procyclidine in isolated hepatocytes, prepared from untreated and from phenobarbital-pretreated rats, is described. 2. Major metabolic pathways are ketone formation on carbon-4 and monohydroxylation in cis-4, trans-4 and (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::566c1d251b1e0df1f09861a4d6533527
https://biblio.vub.ac.be/vubir/metabolism-of-procyclidine-in-isolated-rat-hepatocytes-mechanism-of-diol-formation(943f1878-62e0-48b4-a276-93611139552d).html
https://biblio.vub.ac.be/vubir/metabolism-of-procyclidine-in-isolated-rat-hepatocytes-mechanism-of-diol-formation(943f1878-62e0-48b4-a276-93611139552d).html
Publikováno v:
Vrije Universiteit Brussel
1. The induction and inhibition of some biotransformation enzymes by valproate have been studied in hepatocytes isolated from rats treated with sodium valproate either i.p. or by subcutaneous implantation of osmotic pumps. 2. When valproate was given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c22ad9859d4ec74b631af526c906c588
https://hdl.handle.net/20.500.14017/4c76c22a-2d85-4fde-b7a8-a8f2c5b4b1c8
https://hdl.handle.net/20.500.14017/4c76c22a-2d85-4fde-b7a8-a8f2c5b4b1c8