Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Walter R. Weiss"'
Autor:
Walter R Weiss, Chengyong George Jiang
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31247 (2012)
Live attenuated malaria vaccines are more potent than the recombinant protein, bacterial or viral platform vaccines that have been tested, and an attenuated sporozoite vaccine against falciparum malaria is being developed for humans. In mice, attenua
Externí odkaz:
https://doaj.org/article/54840e0b64a1464391fdc6399e2744f7
Autor:
George Jiang, Meng Shi, Solomon Conteh, Nancy Richie, Glenna Banania, Harini Geneshan, Anais Valencia, Priti Singh, Joao Aguiar, Keith Limbach, Kurt I Kamrud, Jonathan Rayner, Jonathan Smith, Joseph T Bruder, C Richter King, Takafumi Tsuboi, Satoru Takeo, Yaeta Endo, Denise L Doolan, Thomas L Richie, Walter R Weiss
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6559 (2009)
Using newer vaccine platforms which have been effective against malaria in rodent models, we tested five immunization regimens against Plasmodium knowlesi in rhesus monkeys. All vaccines included the same four P. knowlesi antigens: the pre-erythrocyt
Externí odkaz:
https://doaj.org/article/9e6e88399c3947899ccd9b821b2fadf7
Autor:
Walter R Weiss, Anita Kumar, George Jiang, Jackie Williams, Anthony Bostick, Solomon Conteh, David Fryauff, Joao Aguiar, Manmohan Singh, Derek T O'Hagan, Jeffery B Ulmer, Thomas L Richie
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1063 (2007)
BACKGROUND: We have previously described a four antigen malaria vaccine consisting of DNA plasmids boosted by recombinant poxviruses which protects a high percentage of rhesus monkeys against Plasmodium knowlesi (Pk) malaria. This is a multi-stage va
Externí odkaz:
https://doaj.org/article/fa261fe8ad7a46188f4b2cda87b39eeb
Autor:
Eileen D. Villasante, Kimberly A. Edgel, Joao C. Aguiar, Louis J. Picker, John M. Turner, Thomas L. Richie, Jennie Womack, Al Legasse, Paul T. Edlefsen, Isabel Scholz, Andrea Renner, Julia C. Ford, Klaus Früh, Walter R. Weiss, Michael K. Axthelm, Shannon L. Planer, Guangwu Xu, Mikayla Grey, Brandyce St. Laurent, Scott G. Hansen
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210252 (2019)
PLoS ONE
PLoS ONE
The development of a sterilizing vaccine against malaria remains one of the highest priorities for global health research. While sporozoite vaccines targeting the pre-erythrocytic stage show great promise, it has not been possible to maintain efficac
Autor:
Kalpana Gowda, Mark Gold, J. Kevin Baird, Anita Kumar, Sanjai Kumar, Stephen L. Hoffman, Robert W. Gwadz, Joao C. Aguiar, John A. Tine, Walter R. Weiss, William O. Rogers
A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfbbfa5496b61a20b5c181468e17016
https://doi.org/10.1128/iai.69.9.5565-5572.2001
https://doi.org/10.1128/iai.69.9.5565-5572.2001
Autor:
Kurt Kamrud, Walter R. Weiss, Daniel J. Carucci, Jonathan Smith, Carlota Dobaño, Denise L. Doolan, J. D. Chulay
Publikováno v:
The Open Vaccine Journal. 1:27-37
We evaluated the immunogenicity of virus-like replicon particles (VRP) derived from an attenuated strain of the alphavirus Venezuelan equine encephalitis virus, encoding two pre-erythrocytic Plasmodium yoelii antigens, in mice. Three immunizing doses
Autor:
Barbara J. Flynn, Ross M. Kedl, Walter R. Weiss, Richard A. Koup, Joseph J. Mattapallil, Ulrike Wille-Reece, Aaron P. Miles, Karin Loré, Allan Saul, Robert A. Seder, Mario Roederer
Publikováno v:
The Journal of Experimental Medicine
There is a remarkable heterogeneity in the functional profile (quality) of T cell responses. Importantly, the magnitude and/or quality of a response required for protection may be different depending on the infection. Here, we assessed the capacity o
Autor:
Mario Roederer, Barbara J. Flynn, Ross M. Kedl, Richard A. Koup, Walter R. Weiss, Robert A. Seder, Ulrike Wille-Reece, Joseph J. Mattapallil, Karin Loré
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15190-15194
Induction and maintenance of antibody and T cell responses will be critical for developing a successful vaccine against HIV. A rational approach for generating such responses is to design vaccines or adjuvants that have the capacity to activate speci
Autor:
Victoria Majam, Rana Chattopadhyay, Walter R. Weiss, Babita Mahajan, Sanjai Kumar, Rana Nagarkatti, Dewal Jani, Dharmendar Rathore, Hong Zheng
Publikováno v:
Infection and Immunity. 73:5402-5409
Proteins present on the surface of malaria parasites that participate in the process of invasion and adhesion to host cells are considered attractive vaccine targets. Aided by the availability of the partially completed genome sequence of the simian
Autor:
Thomas F. McCutchan, Mike Cranfield, Sanjai Kumar, Margery Sullivan, Thaddeus K. Graczyk, Jun Li, Walter R. Weiss, Darmendar Rathore, K. Christiana Grim
Publikováno v:
Infection and Immunity. 72:2248-2253
The effectiveness of malaria control measures depends not only on the potency of the control measures themselves but also upon the influence of variables associated with the environment. Environmental variables have the capacity either to enhance or