Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Walter N Moss"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296889 (2024)
MYC pre-mRNA is spliced with high fidelity to produce the transcription factor known to regulate cellular differentiation, proliferation, apoptosis, and alternative splicing. The mechanisms underpinning the pre-mRNA splicing of MYC, however, remain m
Externí odkaz:
https://doaj.org/article/19ab9260fc2f46b98c36bf319b6fc5d7
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264025 (2022)
Experimental breakthroughs have provided unprecedented insights into the genes involved in cancer. The identification of such cancer driver genes is a major step in gaining a fuller understanding of oncogenesis and provides novel lists of potential t
Externí odkaz:
https://doaj.org/article/3281e89187ee4696b895142722304d2b
Autor:
Slavica Pavlovic Djuranovic, Jessey Erath, Ryan J Andrews, Peter O Bayguinov, Joyce J Chung, Douglas L Chalker, James AJ Fitzpatrick, Walter N Moss, Pawel Szczesny, Sergej Djuranovic
Publikováno v:
eLife, Vol 9 (2020)
Plasmodium falciparum is a causative agent of human malaria. Sixty percent of mRNAs from its extremely AT-rich (81%) genome harbor long polyadenosine (polyA) runs within their ORFs, distinguishing the parasite from its hosts and other sequenced organ
Externí odkaz:
https://doaj.org/article/d37acee87930453b87d97c561d9b9e5f
Autor:
Jonathan L Chen, Walter N Moss, Adam Spencer, Peiyuan Zhang, Jessica L Childs-Disney, Matthew D Disney
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219210 (2019)
Tauopathies are neurodegenerative diseases that affect millions of people worldwide including those with Alzheimer's disease. While many efforts have focused on understanding the role of tau protein in neurodegeneration, there has been little done to
Externí odkaz:
https://doaj.org/article/a772d2e432454ac4be8e30b6007186dd
Autor:
Collin A O'Leary, Ryan J Andrews, Van S Tompkins, Jonathan L Chen, Jessica L Childs-Disney, Matthew D Disney, Walter N Moss
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0213758 (2019)
The MYC gene encodes a human transcription factor and proto-oncogene that is dysregulated in over half of all known cancers. To better understand potential post-transcriptional regulatory features affecting MYC expression, we analyzed secondary struc
Externí odkaz:
https://doaj.org/article/c7066325bb254a6e98bffdfaa128829e
Autor:
Nathan Ungerleider, Monica Concha, Zhen Lin, Claire Roberts, Xia Wang, Subing Cao, Melody Baddoo, Walter N Moss, Yi Yu, Michael Seddon, Terri Lehman, Scott Tibbetts, Rolf Renne, Yan Dong, Erik K Flemington
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007206 (2018)
Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic
Externí odkaz:
https://doaj.org/article/9c9c9194a5ea46d7998109d83d394e77
Autor:
Elzbieta Lenartowicz, Julita Kesy, Agnieszka Ruszkowska, Marta Soszynska-Jozwiak, Paula Michalak, Walter N Moss, Douglas H Turner, Ryszard Kierzek, Elzbieta Kierzek
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148281 (2016)
Influenza A is a negative sense RNA virus that kills hundreds of thousands of humans each year. Base pairing in RNA is very favorable, but possibilities for RNA secondary structure of the influenza genomic RNA have not been investigated. This work pr
Externí odkaz:
https://doaj.org/article/f63e371d538c45a08620414de2a78073
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005668 (2015)
The long non-coding RNA (lncRNA) Xist is a master regulator of X-chromosome inactivation in mammalian cells. Models for how Xist and other lncRNAs function depend on thermodynamically stable secondary and higher-order structures that RNAs can form in
Externí odkaz:
https://doaj.org/article/508acf4505e84bd69897834bb15b0e77
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141132 (2015)
Influenza A virus is a threat to humans due to seasonal epidemics and infrequent, but dangerous, pandemics that lead to widespread infection and death. Eight segments of RNA constitute the genome of this virus and they encode greater than eight prote
Externí odkaz:
https://doaj.org/article/e28a1edcfde8488293d17ab9efe2fe37
Autor:
Salvatore F Priore, Elzbieta Kierzek, Ryszard Kierzek, Jayson R Baman, Walter N Moss, Lumbini I Dela-Moss, Douglas H Turner
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e70615 (2013)
Influenza A virus is a segmented single-stranded (-)RNA virus that causes substantial annual morbidity and mortality. The transcriptome of influenza A is predicted to have extensive RNA secondary structure. The smallest genome segment, segment 8, enc
Externí odkaz:
https://doaj.org/article/8dbe32b05c904351b2005ec749ed6308