Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Walter M Kalback"'
Autor:
Chera L Maarouf, Tyler A Kokjohn, Douglas G Walker, Charisse M Whiteside, Walter M Kalback, Alexis Whetzel, Lucia I Sue, Geidy Serrano, Sandra A Jacobson, Marwan N Sabbagh, Eric M Reiman, Thomas G Beach, Alex E Roher
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105784 (2014)
Defining the biochemical alterations that occur in the brain during "normal" aging is an important part of understanding the pathophysiology of neurodegenerative diseases and of distinguishing pathological conditions from aging-associated changes. Th
Externí odkaz:
https://doaj.org/article/3f4835cd1a07417d822f3b2bc489143a
Autor:
Jesse M. Hunter, Emma Rodriguez, Walter M. Kalback, Michael Malek-Ahmadi, Alex E. Roher, Ian D. Daugs, Marwan N. Sabbagh, Tyler A. Kokjohn, Thomas G. Beach, Charisse M. Whiteside, Sandra Jacobson, Chera L. Maarouf
Publikováno v:
Journal of Neurotrauma. 30:981-997
Dementia pugilistica (DP), a suite of neuropathological and cognitive function declines after chronic traumatic brain injury (TBI), is present in approximately 20% of retired boxers. Epidemiological studies indicate TBI is a risk factor for neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4532f8472a0058bf74c3fdf1b664e4de
https://doi.org/10.1089/neu.2012.2699
https://doi.org/10.1089/neu.2012.2699
Autor:
John Lopez, Tyler A. Kokjohn, Alex E. Roher, Ian D. Daugs, Lucia I. Sue, Dean C. Luehrs, Jesse M. Hunter, Walter M. Kalback, Eduardo M. Castaño, Thomas G. Beach, Gregory D. Van Vickle, Chera L. Maarouf, Daniel C. Brune
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812:1508-1514
Amyloid-β (Aβ) peptides are intimately involved in the inflammatory pathology of atherosclerotic vascular disease (AVD) and Alzheimer's disease (AD). Although substantial amounts of these peptides are produced in the periphery, their role and signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effea2d41b451e7f192686d4f7e69a77
https://doi.org/10.1016/j.bbadis.2011.07.004
https://doi.org/10.1016/j.bbadis.2011.07.004
Autor:
Marissa Poston, Frederick G Fifield, Walter M. Kalback, Tyler A Kokjohn, Chera L Esh, Alex E Roher, Gregory D. Van Vickle, Daniel C. Brune, Dean C. Luehrs, R. Lyle Patton, Amanda J. Newel, David Westaway, Thomas G. Beach, Joanne McLaurin, John Lopez, Paul E Fraser
Publikováno v:
Biochemistry. 46:10317-10327
We investigated the morphology and biochemistry of the amyloid-beta (Abeta) peptides produced in TgCRND8 Tg mice carrying combined amyloid precursor protein (APP) Swedish (K670M/N671L) and Indiana (V717F) mutations. Histological analyses employing am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa46fb3a33ba9df41737a6bec4bec10d
https://doi.org/10.1021/bi700951u
https://doi.org/10.1021/bi700951u
Autor:
Eliezer Masliah, Daniel C. Brune, Eduardo M. Castaño, Thomas G. Beach, Amanda J. Newel, Alex E. Roher, Gregory D. Van Vickle, Dean C. Luehrs, Tyler A. Kokjohn, John Lopez, Yu Min Kuo, Walter M. Kalback, Chera Esh, Isidro Ferrer, R. Lyle Patton
Publikováno v:
The American Journal of Pathology. 169:1048-1063
Experiments with amyloid-β (Aβ)-42-immunized transgenic mouse models of Alzheimer's disease have revealed amyloid plaque disruption and apparent cognitive function recovery. Neuropathological examination of patients vaccinated against purified Aβ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87997e7c0d22e463f74b80ddbbee8b11
https://doi.org/10.2353/ajpath.2006.060269
https://doi.org/10.2353/ajpath.2006.060269
Autor:
Andrei V. Alexandrov, Chera Esh, Zsolt Garami, Marwan N. Sabbagh, Alex E. Roher, Jeffrey R. Wilson, Linda Vedders, Walter M. Kalback, Tyler A. Kokjohn, Thomas G. Beach
Publikováno v:
Neurological Research. 28:672-678
Recent post-mortem studies have reported that the severity of atheromatous deposits in the circle of Willis is significantly greater, relative to non-demented (ND) elderly persons, in subjects with neuropathologically diagnosed Alzheimer's disease (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c8886f61aebf5d459605d303c682c5
https://doi.org/10.1179/016164106x130470
https://doi.org/10.1179/016164106x130470
Autor:
Lyle Patton, Chera Esh, Dale Schenk, Tyler A. Kokjohn, Dora Games, Walter M. Kalback, Alex E. Roher, Amanda Newell, Steven M. Paul, Daniel C. Brune, John Lopez, Thomas G. Beach, Bernardino Ghetti, Kelly R. Bales, Eduardo M. Castaño
Publikováno v:
Biochemistry. 44:13807-13819
Central to the pathology of Alzheimer's disease (AD) is the profuse accumulation of amyloid-beta (Abeta) peptides in the brain of affected individuals, and several amyloid precursor protein (APP) transgenic (Tg) mice models have been created to mimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ba187a4d0e2bc2306b33559a12e2f5
https://doi.org/10.1021/bi051213+
https://doi.org/10.1021/bi051213+
Autor:
Dean C. Luehrs, Eduardo M. Castaño, Alex E. Roher, Lucia I. Sue, Francoise Gerber, Douglas G. Walker, Bernd Bohrmann, Chera Esh, Thomas G. Beach, Walter M. Kalback, Tyler A. Kokjohn, Afroza Rahman, Claudia Richardson, Raquel Cisneros
Publikováno v:
Neurological Research. 26:525-539
We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6a1edc15e9bc10079cda15198cc010
https://doi.org/10.1179/016164104225017668
https://doi.org/10.1179/016164104225017668
Autor:
Jennifer Childress, Ruben Vidal, Daniel C. Brune, Alex E. Roher, Dean C. Luehrs, Jill R. Murrell, Tyler A. Kokjohn, John Lopez, Chera Esh, Yu Min Kuo, Walter M. Kalback, Nicole Weiss, Bernardino Ghetti, Martin R. Farlow
Publikováno v:
Journal of Biological Chemistry. 279:5829-5836
One of the familial forms of Alzheimer's disease (AD) encodes the amyloid-beta precursor protein (AbetaPP) substitution mutation V717F. This mutation is relevant to AD research, since it has been utilized to generate transgenic mice models to study A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348705cd60b1be3473577de0493bd212
https://doi.org/10.1074/jbc.m311380200
https://doi.org/10.1074/jbc.m311380200
Autor:
Walter M. Kalback, Tyler A. Kokjohn, Thomas G. Beach, Alex E. Roher, James D. Seward, Chera Esh, Dean C. Luehrs, Lucia I. Sue
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:2055-2062
Objectives— We conducted a quantitative investigation of brain arterial atherosclerotic damage and its relationship to sporadic Alzheimer’s disease (AD). Methods and Results— Fifty-four consecutive autopsy cases, 32 AD and 22 nondemented contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993f38d8e0fe348bfdc9b1690313560d
https://doi.org/10.1161/01.atv.0000095973.42032.44
https://doi.org/10.1161/01.atv.0000095973.42032.44