Role of Damage-Associated Molecular Patterns in Light of Modern Environmental Research: A Tautological Approach

Autor: Walter Land

Publikováno v: International Journal of Environmental Research

Two prominent models emerged as a result of intense interdisciplinary discussions on the environmental health paradigm, called the “exposome” concept and the “adverse outcome pathway” (AOP) concept that links a molecular initiating event to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ac650117aae32875a7be4840f3d3dc

Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients

Autor: Christian Meyer, Walter Land, Vincent Legros, Gérard Audibert, Raphael Carapito, Béatrice Uring-Lambert, Alain Meyer, Erik Sauleau, Bernard Geny, Seiamak Bahram, Marie Borel, Pierre Diemunsch, Julien Pottecher, Eric Noll, Sébastien Gette, Elisabeth Gaertner

Publikováno v: Trials
Trials, 2020, 21 (1), pp.274. ⟨10.1186/s13063-020-4141-6⟩
Trials, Vol 21, Iss 1, Pp 1-13 (2020)
Trials, BioMed Central, 2020, 21 (1), pp.274. ⟨10.1186/s13063-020-4141-6⟩

Background Acute respiratory distress syndrome continues to drive significant morbidity and mortality after severe trauma. The incidence of trauma-induced, moderate-to-severe hypoxaemia, according to the Berlin definition, could be as high as 45%. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f0b467813a5f7d198db67629945bb0
http://europepmc.org/articles/PMC7079402

Solid Organ Injury

Autor: Walter Land

Publikováno v: Damage-Associated Molecular Patterns in Human Diseases ISBN: 9783030538675

In this chapter, traumatic and nontraumatic solid organ injuries (including examples of drug-induced and alcohol-related organ injuries) known to cause acute or chronic diseases are neatly described. By referring to selected acute/chronic injury-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73a0e82232cfc6ffb5c981556cbc029d
https://doi.org/10.1007/978-3-030-53868-2_9

Pattern Recognition Molecules

Autor: Walter Land

Publikováno v: Damage-Associated Molecular Patterns in Human Diseases ISBN: 9783030538675

In Chapter 2, a selected, clinically oriented update of pattern recognition molecules (PRMs) is presented, as more comprehensively outlined in Vol. 1 of the book Damage-Associated Molecular Patterns in Human Diseases”: Injury-Induced Innate Immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c62917a3da7ba3389740986d11a00918
https://doi.org/10.1007/978-3-030-53868-2_2

The Growing Clinical Relevance of Cellular Stress Responses and Regulated Cell Death

Autor: Walter Land

Publikováno v: Damage-Associated Molecular Patterns in Human Diseases ISBN: 9783030538675

In this chapter, a selected, clinically oriented update of cellular adaptive stress responses and subroutines of regulated cell death is presented, as already comprehensively outlined in Vol. 1 of the book Damage-Associated Molecular Patterns in Huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ea65cb93139a78b5667a3dbc7e3b695
https://doi.org/10.1007/978-3-030-53868-2_4