Výsledky vyhledávání - "Walter Jonat"

Akademický článek

Reduced ovarian reserve in young early breast cancer patients: preliminary data from a prospective cohort trial

Autor: Antonia Wenners, Jana Grambach, Juliane Koss, Nicolai Maass, Walter Jonat, Andreas Schmutzler, Christoph Mundhenke

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)

Abstract Background The numerous side effects of chemotherapy in patients with breast cancer are well known. However, the precise effects of chemotherapy on ovarian function in premenopausal women are poorly investigated. The patients are at risk of

Externí odkaz: https://doaj.org/article/c9c06d56e5bb43caaf47cb0a5d12683e

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Akademický článek

Cut-Off Levels of Anti-Mullerian Hormone for The Prediction of Ovarian Response, In Vitro Fertilization Outcome and Ovarian Hyperstimulation Syndrome

Autor: Ali Salmassi, Liselotte Mettler, Jurgen Hedderich, Walter Jonat, Anupama Deenadayal, Soeren von Otte, Christel Eckmann-Scholz, Andreas Gerd Schmutzler

Publikováno v: International Journal of Fertility and Sterility, Vol 9, Iss 2, Pp 157-167 (2015)

Background Evaluation of anti-mullerian hormone (AMH) cut-off levels in as- sisted reproductive technology (ART) as predictive factor for individualization of stimulation protocols and to avoid ovarian hyperstimulation syndrome (OHSS). Materials and

Externí odkaz: https://doaj.org/article/1d61d1793e2246e9b7b8f8f23f4fbd58

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Akademický článek

Apoptosis Resistance in Endometriosis

Autor: Liselotte Mettler, Walter Jonat, Frank Püngel, Kerstin Koch, Andreas-G Schmutzler, Bengi Acar-Perk, Ali Salmassi

Publikováno v: BioImpacts, Vol 1, Iss 2, Pp 129-134 (2011)

Introduction: In a cytological analysis of endometriotic lesions neither granulocytes nor cytotoxic T-cells appear in an appreciable number. Based on this observation we aimed to know, whether programmed cell death plays an essential role in the dest

Externí odkaz: https://doaj.org/article/103102e5ed674315bc9f01beda973daf

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Akademický článek

Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer.

Autor: Antonia Sophie Wenners, Keyur Mehta, Sibylle Loibl, Hyerim Park, Berit Mueller, Norbert Arnold, Sigrid Hamann, Joerg Weimer, Beyhan Ataseven, Silvia Darb-Esfahani, Christian Schem, Christoph Mundhenke, Fariba Khandan, Christoph Thomssen, Walter Jonat, Hans-Juergen Holzhausen, Gunther von Minckwitz, Carsten Denkert, Maret Bauer

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e45826 (2012)

In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer (BC) and predicts poor prognosis. In neoadjuvant chemotherapy (NACT) pathological complete re

Externí odkaz: https://doaj.org/article/841329c0b7e94a6baf6f5cc1140a245b

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Akademický článek

DNA-methylation profiling of fetal tissues reveals marked epigenetic differences between chorionic and amniotic samples.

Autor: Christel Eckmann-Scholz, Susanne Bens, Julia Kolarova, Sina Schneppenheim, Almuth Caliebe, Simone Heidemann, Constantin von Kaisenberg, Monika Kautza, Walter Jonat, Reiner Siebert, Ole Ammerpohl

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39014 (2012)

Epigenetic mechanisms including DNA methylation are supposed to play a key role in fetal development. Here we have investigated fetal DNA-methylation levels of 27,578 CpG loci in 47 chorionic villi (CVS) and 16 amniotic cell (AC) samples. Methylation

Externí odkaz: https://doaj.org/article/cfa397a7b12745178807de315511bf56

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