Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Walter J. Wurzer"'
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectiveTo review the current knowledge on bone health in patients with hemophilia A and the underlying pathogenetic mechanisms.Data SourcesOriginal research articles, meta-analyses, and scientific reviews.Data SynthesisAlready in childhood, patient
Externí odkaz:
https://doaj.org/article/c6359ea15ebc4f6fbe65091560838499
Publikováno v:
Canine Genetics and Epidemiology, Vol 6, Iss 1, Pp 1-9 (2019)
Abstract Background Von Willebrand disorder type I (vWDI) is known as an inherited bleeding disorder in different dog breeds following an autosomal recessive inheritance. The Kromfohrländer is a rare dog breed with an increased incidence of unclear
Externí odkaz:
https://doaj.org/article/f82874fb0d4c4564b7cfaa1c36529291
Publikováno v:
Canine Genetics and Epidemiology
Canine Genetics and Epidemiology, Vol 6, Iss 1, Pp 1-9 (2019)
Canine Genetics and Epidemiology, Vol 6, Iss 1, Pp 1-9 (2019)
Background Von Willebrand disorder type I (vWDI) is known as an inherited bleeding disorder in different dog breeds following an autosomal recessive inheritance. The Kromfohrländer is a rare dog breed with an increased incidence of unclear bleeding
Autor:
Oliver Planz, Walter J. Wurzer, Hanns-Joachim Rziha, Stephan Ludwig, Veronika Ölschläger, Ulf R. Rapp, Lothar Stitz, Stephan Pleschka, Timo Fischer
Publikováno v:
Oncogene. 23:6639-6646
Alterations in signalling via the Raf/MEK/ERK pathway interfere with influenza A virus replication in cell culture. While virus yields are reduced in cells expressing dominant-negative Raf or ERK, virus propagation is enhanced upon expression of cons
Autor:
Stephan Ludwig, Walter J. Wurzer, Oliver Planz, Henning Walczak, Stephan Pleschka, Christina Ehrhardt, Thorsten Wolff, Friederike Berberich-Siebelt
Publikováno v:
Journal of Biological Chemistry. 279:30931-30937
Activation of the transcription factor NF-kappaB is a hallmark of infections by viral pathogens including influenza viruses. Because gene expression of many proinflammatory and antiviral cytokines is controlled by this factor, the concept emerged tha
Autor:
Walter J. Wurzer, Stephan Ludwig, Stephan Pleschka, Christian Kardinal, Oliver Planz, Christoph von Eichel-Streiber, Christina Ehrhardt, Thorsten Wolff
Publikováno v:
FEBS Letters. 567:230-238
The anti-viral type I interferon (IFN) response is initiated by the immediate induction of IFN beta, which is mainly controlled by the IFN-regulatory factor-3 (IRF-3). The signaling pathways mediating viral IRF-3 activation are only poorly defined. W
Autor:
Pilaipan Puthavathana, Tobias Silberzahn, Oliver Planz, Igor Mazur, Walter J. Wurzer, Stephan Ludwig, Christina Ehrhardt, Thorsten Wolff, Stephan Pleschka
Publikováno v:
Cellular microbiology. 9(7)
Summary Influenza is still one of the major plagues worldwide. The statistical likeliness of a new pandemic outbreak highlights the urgent need for new and amply avail- able antiviral drugs. We and others have shown that influenza virus misuses the c
Autor:
Christina Ehrhardt, Oliver Planz, Thorsten Wolff, Stephan Ludwig, Stephan Pleschka, Jens Reinhardt, Walter J. Wurzer
Publikováno v:
FEBS letters. 561(1-3)
Influenza A and B viruses are still a major worldwide threat. We demonstrate that influenza B virus infection induces signaling via the Raf/MEK/ERK cascade, a process required for efficient virus production. Expression of dominant-negative Raf and ER
Autor:
Christina Ehrhardt, Oliver Planz, Tobias Silberzahn, Martin Giner, Stephan Ludwig, Stephan Pleschka, Walter J. Wurzer
Publikováno v:
The EMBO journal. 22(11)
Apoptosis is a hallmark event observed upon infection with many viral pathogens, including influenza A virus. The apoptotic process is executed by a proteolytic system consisting of a family of cysteinyl proteases, termed caspases. Since the conseque