Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Walter J. Wojcik"'
Autor:
Walter J. Wojcik
Publikováno v:
Pharmacological research. 64(4)
The Laboratory of Receptor Pharmacology studied the GABAB and muscarinic m2/m3 receptors present in primary cultures of rat cerebellar granule cells. From 1985 to 1992, multiple scientists showed the GABAB receptor had, at least, two affinity states,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6f87c35de317d89aea4d0de029bc8c
https://pubmed.ncbi.nlm.nih.gov/21704162
https://pubmed.ncbi.nlm.nih.gov/21704162
Publikováno v:
Neuroprotocols. 2:59-65
In primary cultures of cerebellar granule cells, an antisense strategy was used to elucidate the structure and function of GABAB receptors that inhibit adenylyl cyclase activity. The muscarinic m2 receptor, also expressed in cerebellar granule cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51ebfb9df663c8b5a9911cb43832e16
https://doi.org/10.1006/ncmn.1993.1009
https://doi.org/10.1006/ncmn.1993.1009
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 227:225-228
The effects of various proposed GABAB receptor antagonists on baclofen-mediated inhibition of adenylyl cyclase were studied in cultured cerebellar granule cells from rat. (+/-)-Baclofen maximally inhibited adenylyl cyclase by approximately 60% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74d16f4c91acf245d94541fc7312f51
https://doi.org/10.1016/0922-4106(92)90132-f
https://doi.org/10.1016/0922-4106(92)90132-f
Publikováno v:
European journal of pharmacology. 245(3)
Activation of muscarinic receptors with carbachol has no effect on intracellular Ca2+ concentration in cerebellar granule cell cultures. Only after elevating intracellular Ca2+ concentrations using either 40 mM KCl or activating glutamatergic recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a47a498e7e8d6d4e563f468205ed431
https://pubmed.ncbi.nlm.nih.gov/8101492
https://pubmed.ncbi.nlm.nih.gov/8101492
Autor:
Ezio Carboni, Walter J. Wojcik
Publikováno v:
Journal of Neurochemistry. 50:1279-1286
In primary cultures of cerebellar granule cells, [3H]nitrendipine binds with high affinity to a single site (KD 1 nM and Bmax 20 fmol/mg protein). The 1,4-dihydropyridine (DHP) class of compounds such as nitrendipine, nifedipine, and BAY K 8644 displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b79e5a14a68f1107212f531c13e86d
https://doi.org/10.1111/j.1471-4159.1988.tb10605.x
https://doi.org/10.1111/j.1471-4159.1988.tb10605.x
Publikováno v:
Journal of Neurochemistry. 53:753-758
gamma-Aminobutyric acidB (GABAB) receptor recognition sites that inhibit cyclic AMP formation, open potassium channels, and close calcium channels are coupled to these effector systems by guanine nucleotide binding proteins (G proteins). These G prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e92b237e727ac3c8b87b9487cb7352
https://doi.org/10.1111/j.1471-4159.1989.tb11769.x
https://doi.org/10.1111/j.1471-4159.1989.tb11769.x
Publikováno v:
Pharmacology Biochemistry and Behavior. 14:371-375
Phenoxybenzamine (10 mg/kg, IP), an α-adrenoreceptor blocker, and bromocriptine (5 mg/kg, IP), a dopamine receptor stimulant, were administered to rats while the animals were being deprived of REM sleep by selective REM sleep deprivation method. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ce178c8b6a4beaf08217a7a133869c
https://doi.org/10.1016/0091-3057(81)90404-4
https://doi.org/10.1016/0091-3057(81)90404-4
Publikováno v:
Neuropharmacology. 21:323-325
alpha-Flupenthixol (0.2 mg/kg, i.p.), a dopamine receptor blocker, significantly increased slow-wave sleep and decreased wakefulness in rats when administered either at the onset of a 12-hr light period or a 12-hr dark period. The same dose of the dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c064add79c2217c00d606a01b8d03e12
https://doi.org/10.1016/0028-3908(82)90095-8
https://doi.org/10.1016/0028-3908(82)90095-8
Autor:
Norton H. Neff, Walter J. Wojcik
Publikováno v:
Neuroscience letters. 41(1-2)
Stimulation of either adenosine A1 or A2 receptors results in a decrease or an increase in the adenylate cyclase activity, respectively. With various concentrations of the adenosine agonist N6-phenylisopropyladenosine, both responses on cyclase are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb38ef2f8af3c63fdeb9a6ad1b4d8af3
https://pubmed.ncbi.nlm.nih.gov/6316221
https://pubmed.ncbi.nlm.nih.gov/6316221
Publikováno v:
Pharmacology, biochemistry, and behavior. 11(3)
The effects of DL 2-amino-3-(1-naphthyl) propanoic acid, a tryptophan analog, on sleep and brain chemistry were investigated in rats. Similar to previous findings with tryptophan, the tryptophan analog (30 mg/kg, IP) reduced slow-wave sleep (SWS) lat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c4776236712336e85c77b12fec7119
https://pubmed.ncbi.nlm.nih.gov/504312
https://pubmed.ncbi.nlm.nih.gov/504312