Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Walter J. Koskinen"'
Publikováno v:
Tissue Antigens. 67:237-240
Certain HLA class II alleles have been reported to play a role in development or prevention of cervical carcinoma, an epithelial malignancy linked to human papillomavirus (HPV). In head and neck carcinomas, of which a subset is also HPV associated, t
Autor:
Pia Alhopuro, Timo Atula, Sinikka Suominen, Walter J. Koskinen, Lauri A. Aaltonen, Pia Vahteristo, Leena-Maija Aaltonen, Ilmo Leivo, Risto Kontio, Petri Bono, Helinä Järvinen, Mecklin Jp, Johanna Arola, Antti Mäkitie, Sanna K. Ylisaukko-oja
Publikováno v:
Journal of Medical Genetics. 42:694-698
Background: MDM2 acts as a principal regulator of the tumour suppressor p53 by targeting its destruction through the ubiquitin pathway. A polymorphism in the MDM2 promoter (SNP309) was recently identified. SNP309 was shown to result, via Sp1, in high
Autor:
Heikki Joensuu, Marjut Puputti, Olli Tynninen, Laura Pulli, Walter J. Koskinen, Aija Knuuttila, Minna Tanner, Nina N. Nupponen, Ralf Bützow, Harri Sihto, Tapio Visakorpi, Tom Böhling, Leena-Maija Aaltonen
Publikováno v:
Journal of Molecular Medicine. 83:976-983
Mutations that may predict response to adenosine 5'-triphosphate (ATP)-mimetic epidermal growth factor receptor (EGFR) inhibitors occur in the EGFR kinase domain in lung adenocarcinomas and bronchioloalveolar carcinomas (BACs). Data on the frequency
Autor:
Antti Mäkitie, Marie Lundberg, Leena-Maija Aaltonen, Walter J. Koskinen, Mervi Pajusto, Petri S. Mattila
Publikováno v:
Headneck. 31(5)
Background. Transforming growth factor b (TGF- b) is a pleiotropic cytokine that has diverse roles in cancer. Rate of production of the major isoform, TGF-b1, is linked with rs1982073 single nucleotide polymorphism in TGFB1 gene sig- nal sequence. Me
Autor:
Ilmari Pyykkö, Antti Vaheri, Hanna Dahlstrand, Tapio Luostarinen, Tov Røysland, Walter J. Koskinen, Wim Quint, Anco Molijn, Joakim Dillner, Timo Hakulinen, Ilmo Leivo, Antti Mäkitie, Kjell Brøndbo, Eva Munck-Wikland, Leena-Maija Aaltonen
Publikováno v:
Journal of cancer research and clinical oncology. 133(9)
Human papillomavirus (HPV) has been linked to oropharyngeal carcinomas, but its role in laryngeal squamous cell carcinoma (LSCC) is not clear. A prospective multicenter study based on known tumor-cell percentage of fresh frozen carcinoma biopsies was
Autor:
Heikki Joensuu, Ilmo Leivo, Antti Vaheri, Walter J. Koskinen, Petri Bono, Leena-Maija Aaltonen
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 77(2)
Background and purpose Early stage vocal cord carcinomas are usually cured by radiation therapy despite the use of portals that exclude the cervical lymph nodes. We investigated whether the lymphatic vessel density (LVD) of vocal cord carcinomas diff
Autor:
Walter J, Koskinen, Ren Wei, Chen, Ilmo, Leivo, Antti, Mäkitie, Leif, Bäck, Risto, Kontio, Riitta, Suuronen, Christian, Lindqvist, Eeva, Auvinen, Anco, Molijn, Wim G, Quint, Antti, Vaheri, Leena-Maija, Aaltonen
Publikováno v:
International journal of cancer. 107(3)
Fresh-frozen biopsies were obtained from 61 patients at diagnosis of squamous cell carcinoma of the head and neck (HNSCC) for study of the prevalence and physical status of human papillomavirus (HPV) DNA. The frequency of HPV DNA and genotypes were d