Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Walter J Lukiw"'
Autor:
Grzegorz A Czapski, Magdalena Cieślik, Emilia Białopiotrowicz, Walter J Lukiw, Joanna B Strosznajder
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259740 (2021)
In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid
Externí odkaz:
https://doaj.org/article/8127807ac86f483683a94cab32ca2f3b
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150211 (2016)
The aggregation of Aβ42-peptides and the formation of drusen in age-related macular degeneration (AMD) are due in part to the inability of homeostatic phagocytic mechanisms to clear self-aggregating Aβ42-peptides from the extracellular space. The t
Externí odkaz:
https://doaj.org/article/789515a8a31744e38b3320296ffc0e92
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Externí odkaz:
https://doaj.org/article/d23857842ecf4e49a68e19b6b4ddfb08
Autor:
Yuhai eZhao, James M Hill, Surjyadipta eBhattacharjee, Maire E. Percy, Aileen I.D. Pogue, Walter J Lukiw
Publikováno v:
Frontiers in Neurology, Vol 5 (2014)
Externí odkaz:
https://doaj.org/article/41faa5c1373c48f28e7b4e6b168f4a13
Publikováno v:
Frontiers in Genetics, Vol 3 (2013)
Alzheimer’s disease (AD) is a tragic, progressive, age-related neurological dysfunction, representing one of the most prevalent neurodegenerative disorders in industrialized societies. Globally, 5 million new cases of AD are diagnosed annually, wit
Externí odkaz:
https://doaj.org/article/c349b7d469714ea993c161bd96231ac4
Autor:
Yuhai Zhao, Frederic Calon, Carl Julien, Jeremy W Winkler, Nicos A Petasis, Walter J Lukiw, Nicolas G Bazan
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15816 (2011)
Neuroprotectin D1 (NPD1) is a stereoselective mediator derived from the omega-3 essential fatty acid docosahexaenoic acid (DHA) with potent inflammatory resolving and neuroprotective bioactivity. NPD1 reduces Aβ42 peptide release from aging human br
Externí odkaz:
https://doaj.org/article/29284e9ca86646f4998ee89a6a7662ec
Autor:
Walter J. Lukiw
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/8782182a4c474a2a89fd86455473c284
Autor:
Walter J. Lukiw
Publikováno v:
Biology, Vol 12, Iss 6, p 788 (2023)
AD is a complex, progressive, age-related neurodegenerative disorder representing the most common cause of senile dementia and neurological dysfunction in our elderly domestic population. The widely observed heterogeneity of AD is a reflection of the
Externí odkaz:
https://doaj.org/article/c25aefb711c24277aa592b94f5d368c2
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Microbiome-derived Gram-negative bacterial lipopolysaccharide (LPS) has been shown by multiple laboratories to reside within Alzheimer's disease (AD)-affected neocortical and hippocampal neurons. LPS and other pro-inflammatory stressors strongly indu
Externí odkaz:
https://doaj.org/article/884d6fdb094a4b52bd54f89e01a70770
Autor:
Walter J. Lukiw
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/ffc3fb1c77b7439d8c2881b3ef9304ee