Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Walter J, Loos"'
Autor:
Ron H.J. Mathijssen, Jaap Verweij, Bronno van der Holt, Erik A.C. Wiemer, Leni van Doorn, Jessica M. van der Bol, Sharyn D. Baker, Lena E. Friberg, Walter J. Loos, Anne-Joy M. de Graan
CCR Translation for This Article from Influence of Smoking on the Pharmacokinetics and Toxicity Profiles of Taxane Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cccf84a2ffead2b3c6da53aa251d99
https://doi.org/10.1158/1078-0432.22447011
https://doi.org/10.1158/1078-0432.22447011
Autor:
Ugo De Giorgi, Ron H.J. Mathijssen, Walter J. Loos, Jaap Verweij, Erik A.C. Wiemer, Gaia Schiavon, Lena E. Friberg, Winette T.A. van der Graaf, Alex Sparreboom, Floris A. de Jong, An K. Reyners, Martin N. Fransson, Karel Eechoute
PDF file, 77K, Association analysis between imatinib trough concentrations and progression free survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51daa89020b3e98ec085c090f485a091
https://doi.org/10.1158/1078-0432.22446557.v1
https://doi.org/10.1158/1078-0432.22446557.v1
Autor:
Ugo De Giorgi, Ron H.J. Mathijssen, Walter J. Loos, Jaap Verweij, Erik A.C. Wiemer, Gaia Schiavon, Lena E. Friberg, Winette T.A. van der Graaf, Alex Sparreboom, Floris A. de Jong, An K. Reyners, Martin N. Fransson, Karel Eechoute
Purpose: Imatinib minimal (trough) plasma concentrations after one month of treatment have shown a significant association with clinical benefit in patients with gastrointestinal stromal tumors (GIST). Considering that a retrospective pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4cc6ed9194fc8f49fdcca8c198760d
https://doi.org/10.1158/1078-0432.c.6520784
https://doi.org/10.1158/1078-0432.c.6520784
Autor:
Adriaan A. Lammertsma, Egbert F. Smit, Pieter E. Postmus, N. Harry Hendrikse, Albert D. Windhorst, Jonas Eriksson, Hugo B. Rutten, Emile F.I. Comans, Henri N. Greuter, Gerarda J.M. Herder, Walter J. Loos, Ron H.J. Mathijssen, Mark Lubberink, Astrid A.M. van der Veldt
PDF File - 77K, Supplementary data showing measurements in evaluable tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9158d33cd2ed944aa82823bbcc4b18
https://doi.org/10.1158/1078-0432.22448435.v1
https://doi.org/10.1158/1078-0432.22448435.v1
Autor:
Adriaan A. Lammertsma, Egbert F. Smit, Pieter E. Postmus, N. Harry Hendrikse, Albert D. Windhorst, Jonas Eriksson, Hugo B. Rutten, Emile F.I. Comans, Henri N. Greuter, Gerarda J.M. Herder, Walter J. Loos, Ron H.J. Mathijssen, Mark Lubberink, Astrid A.M. van der Veldt
Purpose: Pharmacokinetics of docetaxel can be measured in vivo using positron emission tomography (PET) and a microdose of radiolabeled docetaxel ([11C]docetaxel). The objective of this study was to investigate whether a [11C]docetaxel PET microdosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c422c5b4af07fd9d840db68cdb08de0
https://doi.org/10.1158/1078-0432.c.6521399.v1
https://doi.org/10.1158/1078-0432.c.6521399.v1
Autor:
Alex Sparreboom, Ron H. J. Mathijssen, Sharyn D. Baker, Ron H. N. van Schaik, Walter J. Loos, Guoqing Du, Aisha L. Walker, Torben S. Mikkelsen, Thomas J. Corydon, Gitte H. Bruun, Alice A. Gibson, Shuiying Hu, Peter de Bruijn, Lena E. Friberg, Laure Elens, Bruno Hagenbuch, Amanda Obaidat, Cynthia S. Lancaster, Anne-Joy M. de Graan
Purpose: Docetaxel is extensively metabolized by CYP3A4 in the liver but mechanisms by which the drug is taken up into hepatocytes remain poorly understood. We hypothesized that (i) liver uptake of docetaxel is mediated by the polymorphic solute carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9507febb19ac51c0604f54e8b793f49f
https://doi.org/10.1158/1078-0432.c.6521042
https://doi.org/10.1158/1078-0432.c.6521042
Autor:
Stefan Sleijfer, Elisabeth G.E. de Vries, Walter J. Loos, Ferry A.L.M. Eskens, Renée Miceli, Norma Lynn Fox, Jourik A. Gietema, Corina N.A.M. Oldenhuis, Jaap Verweij, Constantijne H. Mom
Purpose: To evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of mapatumumab, a fully human monoclonal antibody targeting tumor necrosis factor–related apoptosis–inducing ligand receptor 1 (TRAIL-R1), in combination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779847d0afdfec1bc8c30e167dc82886
https://doi.org/10.1158/1078-0432.c.6517948.v1
https://doi.org/10.1158/1078-0432.c.6517948.v1
Autor:
Floris A. de Jong, Alex Sparreboom, Jaap Verweij, Lena E. Friberg, Erik A.C. Wiemer, Walter J. Loos, André S.Th. Planting, Geert-Jan M. Creemers, Ron H.J. Mathijssen, Jessica M. van der Bol
Purpose: Irinotecan, the prodrug of SN-38, is extensively metabolized by cytochrome P450-3A4 (CYP3A4). A randomized trial was done to assess the utility of an algorithm for individualized irinotecan dose calculation based on a priori CYP3A4 activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb9f4c1adf600933dbc0d597f681741
https://doi.org/10.1158/1078-0432.c.6517789.v1
https://doi.org/10.1158/1078-0432.c.6517789.v1
Autor:
Floris A. de Jong, Alex Sparreboom, Jaap Verweij, Lena E. Friberg, Erik A.C. Wiemer, Walter J. Loos, André S.Th. Planting, Geert-Jan M. Creemers, Ron H.J. Mathijssen, Jessica M. van der Bol
CCR Translation for this Article from A CYP3A4 Phenotype–Based Dosing Algorithm for Individualized Treatment of Irinotecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c48407ec768a909fa059f6fb048b55a
https://doi.org/10.1158/1078-0432.22440463.v1
https://doi.org/10.1158/1078-0432.22440463.v1
Autor:
Ugo De Giorgi, Ron H.J. Mathijssen, Walter J. Loos, Jaap Verweij, Erik A.C. Wiemer, Gaia Schiavon, Lena E. Friberg, Winette T.A. van der Graaf, Alex Sparreboom, Floris A. de Jong, An K. Reyners, Martin N. Fransson, Karel Eechoute
CCR Translation for This Article from A Long-term Prospective Population Pharmacokinetic Study on Imatinib Plasma Concentrations in GIST Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4688cbd70f27587b463a23736d2c1a1a
https://doi.org/10.1158/1078-0432.22446563.v1
https://doi.org/10.1158/1078-0432.22446563.v1