Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Walter J, Akers"'
Autor:
Richard H. Chapple, Xueying Liu, Sivaraman Natarajan, Margaret I. M. Alexander, Yuna Kim, Anand G. Patel, Christy W. LaFlamme, Min Pan, William C. Wright, Hyeong-Min Lee, Yinwen Zhang, Meifen Lu, Selene C. Koo, Courtney Long, John Harper, Chandra Savage, Melissa D. Johnson, Thomas Confer, Walter J. Akers, Michael A. Dyer, Heather Sheppard, John Easton, Paul Geeleher
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Background Neuroblastoma is a common pediatric cancer, where preclinical studies suggest that a mesenchymal-like gene expression program contributes to chemotherapy resistance. However, clinical outcomes remain poor, implying we need a bette
Externí odkaz:
https://doaj.org/article/fc1c31cafd514273af4f2d422016e1f2
Autor:
Deep Hathi, Chantiya Chanswangphuwana, Nicholas Cho, Francesca Fontana, Dolonchampa Maji, Julie Ritchey, Julie O’Neal, Anchal Ghai, Kathleen Duncan, Walter J. Akers, Mark Fiala, Ravi Vij, John F. DiPersio, Michael Rettig, Monica Shokeen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Multiple myeloma (MM) is a cancer of bone marrow (BM) plasma cells, which is increasingly treatable but still incurable. In 90% of MM patients, severe osteolysis results from pathological interactions between MM cells and the bone microenvir
Externí odkaz:
https://doaj.org/article/8e51a8a6e17d4addb9f29bbbabe3d928
Autor:
Shahinur Alam, Tae-Yeon Eom, Jeffrey Steinberg, David Ackerman, J. Eric Schmitt, Walter J. Akers, Stanislav S. Zakharenko, Khaled Khairy
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Segmentation of mouse brain magnetic resonance images (MRI) based on anatomical and/or functional features is an important step towards morphogenetic brain structure characterization of murine models in neurobiological studies. State-of-the-art image
Externí odkaz:
https://doaj.org/article/aac3d470352c401981a4b0f9a087742b
Autor:
T. Blaine Crowley, Beverly S. Emanuel, Khaled Khairy, Walter J. Akers, Stanislav S. Zakharenko, R. Sean Gallagher, Jeffrey Steinberg, J. Eric Schmitt, Shahinur Alam, David R. Roalf, Ruben C. Gur, Donna M. McDonald-McGinn, Raquel E. Gur, Kosha Ruparel, Tae-Yeon Eom, Aaron Alexander-Bloch, John J. DeBevits
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 8:79-90
The presence of a 22q11.2 microdeletion (22q11.2 deletion syndrome [22q11DS]) ranks among the greatest known genetic risk factors for the development of psychotic disorders. There is emerging evidence that the cerebellum is important in the pathophys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b685c5d0611a2a0d61f0712bd0f785
https://doi.org/10.1016/j.bpsc.2021.11.008
https://doi.org/10.1016/j.bpsc.2021.11.008
Autor:
Richard H. Chapple, Xueying Liu, Sivaraman Natarajan, Margaret I.M. Alexander, Yuna Kim, Anand G. Patel, Christy W. LaFlamme, Min Pan, William C. Wright, Hyeong-Min Lee, Yinwen Zhang, Meifen Lu, Selene C. Koo, Courtney Long, John Harper, Chandra Savage, Melissa D. Johnson, Thomas Confer, Walter J. Akers, Michael A. Dyer, Heather Sheppard, John Easton, Paul Geeleher
Neuroblastoma is a common pediatric cancer, where preclinical studies have suggested chemotherapy resistance is driven by a mesenchymal-like gene expression program. However, the poor clinical outcomes imply we need a better understanding of the rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ac36f096d7467cac33a3f05a5d353e
https://doi.org/10.1101/2023.04.13.536639
https://doi.org/10.1101/2023.04.13.536639
Autor:
Michael A. Dyer, Abbas Shirinifard, Walter J. Akers, Shantel Brown, Jacqueline L. Norrie, Ardiana Moustaki, Rosa Nguyen
Supplementary Figure S2. Cytotoxic activity of NK cells from CD1-Foxn1nu mice. A, The MHC class II-deficient mouse lymphoma cell line, YAC-1, was used to test NK cell cytotoxicity. B, IL-2 (dark gray) or IL-15-activated (light gray) NK cells isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804fb220d18d30992686b5277c08acc7
https://doi.org/10.1158/1078-0432.22472297.v1
https://doi.org/10.1158/1078-0432.22472297.v1
Autor:
Monica Shokeen, Katherine N. Weilbaecher, Andre D'avignon, Walter J. Akers, Kooresh I. Shoghi, Roberto Civitelli, Simone Cenci, Jingyu Xiang, Deep Hathi, Xinming Su, Xia Ge, Francesca Fontana
NMR measurement: Sample preparation and analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2705338109c3232f572e855ef0536cf
https://doi.org/10.1158/1078-0432.22460492
https://doi.org/10.1158/1078-0432.22460492
Autor:
Michael A. Dyer, Abbas Shirinifard, Walter J. Akers, Shantel Brown, Jacqueline L. Norrie, Ardiana Moustaki, Rosa Nguyen
Purpose:Immunotherapy with IL2, GM-CSF, and an anti-disialoganglioside (GD2) antibody significantly increases event-free survival in children with high-risk neuroblastoma. However, therapy failure in one third of these patients and IL2-related toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3ec04cf45e82985e0f44ff1f61b66a
https://doi.org/10.1158/1078-0432.c.6528188
https://doi.org/10.1158/1078-0432.c.6528188
Autor:
Monica Shokeen, Katherine N. Weilbaecher, Andre D'avignon, Walter J. Akers, Kooresh I. Shoghi, Roberto Civitelli, Simone Cenci, Jingyu Xiang, Deep Hathi, Xinming Su, Xia Ge, Francesca Fontana
Purpose: We hypothesized that in multiple myeloma cells (MMC), high membrane biosynthesis will induce acetate uptake in vitro and in vivo. Here, we studied acetate metabolism and targeting in MMC in vitro and tested the efficacy of 11C-acetate–posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5185384ae6a26e323d5f3e5921de88
https://doi.org/10.1158/1078-0432.c.6524510.v1
https://doi.org/10.1158/1078-0432.c.6524510.v1
Autor:
Monica Shokeen, Katherine N. Weilbaecher, Andre D'avignon, Walter J. Akers, Kooresh I. Shoghi, Roberto Civitelli, Simone Cenci, Jingyu Xiang, Deep Hathi, Xinming Su, Xia Ge, Francesca Fontana
supplemental figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3965a413068e165bb97786add111ff88
https://doi.org/10.1158/1078-0432.22460489.v1
https://doi.org/10.1158/1078-0432.22460489.v1