Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Walter Hofer"'
Autor:
Walter Hofer, Emilia Oueis, Antoine Abou Fayad, Felix Deschner, Anastasia Andreas, Laìs Pessanha de Carvalho, Stephan Hüttel, Steffen Bernecker, Linda Pätzold, Bernd Morgenstern, Nestor Zaburannyi, Markus Bischoff, Marc Stadler, Jana Held, Jennifer Herrmann, Rolf Müller
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad6f1cf88a36ef1fb5db1a7216bda1bf
https://doi.org/10.1002/ange.202202816
https://doi.org/10.1002/ange.202202816
Autor:
Arne Bublitz, Madita Brauer, Stefanie Wagner, Walter Hofer, Mathias Müsken, Felix Deschner, Till R. Lesker, Meina Neumann-Schaal, Lena-Sophie Paul, Ulrich Nübel, Jürgen Bartel, Andreas M. Kany, Daniela Zühlke, Steffen Bernecker, Rolf Jansen, Susanne Sievers, Katharina Riedel, Jennifer Herrmann, Rolf Müller, Thilo M. Fuchs, Till Strowig
Publikováno v:
Cell Host & Microbe. 31:734-750.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073bfbd27b0c59c957cac80f4e6412ba
https://doi.org/10.1016/j.chom.2023.04.003
https://doi.org/10.1016/j.chom.2023.04.003
Autor:
Walter Hofer, Emilia Oueis, Antoine Abou Fayad, Felix Deschner, Anastasia Andreas, Laìs Pessanha de Carvalho, Stephan Hüttel, Steffen Bernecker, Linda Pätzold, Bernd Morgenstern, Nestor Zaburannyi, Markus Bischoff, Marc Stadler, Jana Held, Jennifer Herrmann, Rolf Müller
Publikováno v:
Angewandte Chemie (International ed. in English). 61(30)
The rise of antimicrobial resistance poses a severe threat to public health. The natural product chlorotonil was identified as a new antibiotic targeting multidrug resistant Gram-positive pathogens and Plasmodium falciparum. Although chlorotonil show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda7be105886d98fbfe21bd368059127
https://pubmed.ncbi.nlm.nih.gov/35485800
https://pubmed.ncbi.nlm.nih.gov/35485800
Autor:
Ingrid R. Vetter, Dale Corkery, Luca Laraia, Nelli Erwin, Herbert Waldmann, Maja Köhn, Pablo Rios-Munoz, Roland Winter, Mridula Dwivedi, Walter Hofer, Lei Li, Yao-Wen Wu, Malte Metz, Beate Schölermann, Andreas Brockmeyer, Laura Klewer, Alexandra Friese, Petra Janning, Hacer Karatas, Georgios Konstantinidis, Slava Ziegler
Publikováno v:
Nature Chemical Biology
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Autophagy mediates the degradation of damaged proteins, organelles and pathogens, and plays a key role in health and disease. Thus, the identification of new mechanisms involved in the regulation of autophagy is of major interest. In particular, litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6765c89454ca57ec6764c54a0bf42a5
https://doi.org/10.1038/s41589-019-0307-5
https://doi.org/10.1038/s41589-019-0307-5
Autor:
Tom N. Grossmann, Philipp M. Cromm, Walter Hofer, Elisabeth Hennes, Philipp Küchler, Elisabetta Chiarparin, Herbert Waldmann, Shobhna Kapoor, David Longmire, Paul R. J. Davey, Hélène Adihou, Mercedes Vazquez-Chantada
Publikováno v:
ChemBioChem, 20(24), 2987-2990. Wiley-VCH Verlag
Cromm, P M, Adihou, H, Kapoor, S, Vazquez-Chantada, M, Davey, P, Longmire, D, Hennes, E, Hofer, W, Küchler, P, Chiarparin, E, Waldmann, H & Grossmann, T N 2019, ' Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 ', ChemBioChem, vol. 20, no. 24, pp. 2987-2990 . https://doi.org/10.1002/cbic.201900615
Chembiochem
Cromm, P M, Adihou, H, Kapoor, S, Vazquez-Chantada, M, Davey, P, Longmire, D, Hennes, E, Hofer, W, Küchler, P, Chiarparin, E, Waldmann, H & Grossmann, T N 2019, ' Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 ', ChemBioChem, vol. 20, no. 24, pp. 2987-2990 . https://doi.org/10.1002/cbic.201900615
Chembiochem
The acyl‐binding UNC119 proteins mediate the activation and transport of various N‐myristoylated proteins. In particular, UNC119a plays a crucial role in the completion of cytokinesis. Herein, we report the use of a lipidated peptide originating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a44fabdad54efc230d88f99c2ae89c
https://research.vu.nl/en/publications/72bfb642-0cf7-4fb0-8818-6aab2bf16fa9
https://research.vu.nl/en/publications/72bfb642-0cf7-4fb0-8818-6aab2bf16fa9
Autor:
Christina Janko, Natalia I. Shtemenko, Walter Hofer, A. V. Shtemenko, Christoph Alexiou, Andriy Mokhir, Steffen Daum, Svetlana Babiy, Helen Konovalova
Publikováno v:
Journal of Inorganic Biochemistry. 178:9-17
Aminoferrocene-based prodrugs are activated in cancer cells by reactive oxygen species (ROS). They were shown to exhibit high cytotoxicity towards a variety of cancer cell lines and primary cancer cells, but remain not toxic towards non-malignant cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07f0aa14861560a05dc55e3733ce87f
https://doi.org/10.1016/j.jinorgbio.2017.08.038
https://doi.org/10.1016/j.jinorgbio.2017.08.038
Autor:
Tom Mejuch, Christiane Ehrt, Guillaume Garivet, Nadine Kaiser, Walter Hofer, Alfred Wittinghofer, Slava Ziegler, Matthias Baumann, Eyad K. Fansa, Oliver Koch, Herbert Waldmann
Publikováno v:
Angewandte Chemie International Edition. 56:6181-6186
N-Terminal myristoylation facilitates membrane binding and activity of proteins, in particular of Src family kinases, but the underlying mechanisms are only beginning to be understood. The chaperones UNC119A/B regulate the cellular distribution and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff61a1d73849ab8aeab53ed29c3bbf5e
https://doi.org/10.1002/anie.201701905
https://doi.org/10.1002/anie.201701905
Autor:
Guillaume Garivet, Philippe I. H. Bastiaens, Alfred Wittinghofer, Herbert Waldmann, Rania Alsaabi, Nadine Kaiser, Tom Mejuch, Antonios D. Konitsiotis, Walter Hofer, Christian Klein, Eyad K. Fansa
Publikováno v:
Cell Chemical Biology
Summary Interference with the signaling activity of the N-myristoylated nonreceptor protein tyrosine kinase Src is considered a viable approach in anti-cancer drug discovery. However, ATP-competitive Src inhibitors have not reached the clinic yet and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d80afbc74cd5de416936401e5d66ff
https://hdl.handle.net/21.11116/0000-0003-57F5-721.11116/0000-0003-5A69-3
https://hdl.handle.net/21.11116/0000-0003-57F5-721.11116/0000-0003-5A69-3
Autor:
Mercedes Vazquez-Chantada, Shobhna Kapoor, David Longmire, Elisabeth Hennes, Paul R. J. Davey, Philipp Küchler, Hélène Adihou, Herbert Waldmann, Walter Hofer, Tom N. Grossmann, Elisabetta Chiarparin, Philipp M. Cromm
Publikováno v:
ChemBioChem. 20:2971-2971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::336a3624caf94bd8a59e7624a2b0300b
https://doi.org/10.1002/cbic.201900704
https://doi.org/10.1002/cbic.201900704
Publikováno v:
Neuroscience Letters. 458:106-110
Gephyrin is a major postsynaptic scaffolding protein at GABAergic and glycinergic inhibitory synapses. Gephyrin-deficient (geph(-/-)) mice die after birth due to disinhibition of motor and sensory pathways resulting from a lack of postsynaptic glycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc34f6178b43d6af6ba15196b435675
https://doi.org/10.1016/j.neulet.2009.04.036
https://doi.org/10.1016/j.neulet.2009.04.036