Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Walter Garcia-Ubbelohde"'
Autor:
Richard C, Dart, Sean P, Bush, Kennon, Heard, Thomas C, Arnold, Mark, Sutter, Danielle, Campagne, Christopher P, Holstege, Steven A, Seifert, Jean C Y, Lo, Dan, Quan, Stephen, Borron, David A, Meurer, Randy I, Burnham, Jude, McNally, Walter, Garcia-Ubbelohde, Victoria E, Anderson
Publikováno v:
Annals of emergency medicine. 74(3)
The antivenom currently available for treatment of systemic black widow envenomation (latrodectism) is composed of equine whole immunoglobin. Although considered effective, it has been associated with anaphylaxis and 2 reported fatalities. We test th
Autor:
Elizabeth A. Spradley, Christopher P. Holstege, Richard C. Dart, Thomas C. Arnold, Gregory W. Hendey, Kennon Heard, Gregory M. Bogdan, Becki Bucher Bartelson, Sean P. Bush, Richard C. Clark, Walter Garcia-Ubbelohde
Publikováno v:
Annals of Emergency Medicine. 61:458-467
Study objective Black widow spider antivenom has never been tested in a randomized clinical trial, to our knowledge. We explore various efficacy measures for a novel F(ab)2 antivenom in patients with moderate to severe pain caused by black widow spid
Autor:
Walter Garcia-Ubbelohde, Alejandro Alagón, Carlos Sevcik, Alfredo Luis Chávez-Haro, Jorge F. Paniagua-Solís, Hilda Vázquez
Publikováno v:
International Immunopharmacology. 10:1318-1324
This paper presents the first study of F(ab')(2) scorpion antivenom pharmacokinetics in humans after intramuscular (im) administration. The specific anti-Centruroides scorpion antivenom was used in 6 human healthy volunteers. The fabotherapeutic was
Autor:
Stephen Hardiman, Walter Garcia-Ubbelohde, Ariana Chávez-Méndez, Robert A. Berg, Leslie V. Boyer, Andreas A. Theodorou, Alejandro Alagón, Joanne Mallie
Publikováno v:
New England Journal of Medicine. 360:2090-2098
Clinically significant scorpion envenomation by Centruroides sculpturatus produces a dramatic neuromotor syndrome and respiratory insufficiency that often necessitate intensive supportive care. We hypothesized that a scorpion-specific F(ab')(2) antiv
Autor:
Walter Garcia-Ubbelohde, Ives De Chazal, Gary R. Figge, William J. Meggs, Steven A. Seifert, Sean P. Bush, Richard Gerkin, Stephen W. Borron, David L. Morgan, Leslie V. Boyer, Robert Wolk, Farshad Shirazi, Alejandro Alagón, Dan Quan, Anne Michelle Ruha, Dawn R. Sollee, Brandon Lewis, Richard F. Clark, Thomas C. Arnold, Eric A. Toschlog
Publikováno v:
Clinical toxicology (Philadelphia, Pa.), vol 53, iss 1
Bush, SP; Ruha, AM; Seifert, SA; Morgan, DL; Lewis, BJ; Arnold, TC; et al.(2015). Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial. Clinical Toxicology, 53(1), 37-45. doi: 10.3109/15563650.2014.974263. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9jb32459
Clinical Toxicology (Philadelphia, Pa.)
Bush, SP; Ruha, AM; Seifert, SA; Morgan, DL; Lewis, BJ; Arnold, TC; et al.(2015). Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial. Clinical Toxicology, 53(1), 37-45. doi: 10.3109/15563650.2014.974263. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9jb32459
Clinical Toxicology (Philadelphia, Pa.)
Background . Crotalidae Polyvalent Immune Fab (Ovine) has been the only antivenom commercially available in the US since 2007 for treatment of Crotalinae envenomation. Late coagulopathy can occur or recur after clearance of Fab antivenom, often after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c04d983361d260a18960fe973465a6
https://escholarship.org/uc/item/9jb32459
https://escholarship.org/uc/item/9jb32459
Autor:
Walter Garcia-Ubbelohde, Carlos Sevcik, Alejandro Alagón, R. Mancilla-Nava, Alfredo Luis Chávez-Haro, Jorge F. Paniagua-Solís, Hilda Vázquez
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 46(7)
This paper presents the first study of F(ab')2 scorpion antivenom pharmacokinetics in humans. We have studied the pharmacokinetics of an antiscorpion venom preparation (Alacramyn) in eight human healthy volunteers. The fabotherapic was administered a
Autor:
Yepci Yee, Rafael Bojalil, Edna Sánchez-Castrejón, Alexei F. Licea-Navarro, Jorge F. Paniagua-Solís, María Teresa Mata-González, Luis M. Amezcua-Guerra, Lucía Bolaños, R. Márquez-Velasco, Tanya A. Camacho-Villegas, Fausto Sánchez-Muñoz, Walter Garcia-Ubbelohde, Iván Argueta
Publikováno v:
BMC Immunology
Background In sepsis, tumor necrosis factor (TNF) is the key factor triggering respiratory burst, tissue injury and disseminated coagulation. Anti-TNF strategies based on monoclonal antibodies or F(ab’)2 fragments have been used in sepsis with cont